Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Neha, Srikumar"'
Autor:
Cong, Wu, Ryan, Cook, Ping, Wu, Neha, Srikumar, Elin, Chee, William S, Sawyer, Hua, Wang, Meredith, Hazen, Isidro, Hotzel, Elsa-Noah, N'Diaye, Ning, Ding, Yichin, Liu, John C, Tran, Zhengmao, Ye
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:6601-6610
Proteases are critical proteins involved in cleaving substrates that may impact biological pathways, cellular processes, or disease progression. In the biopharmaceutical industry, modulating the levels of protease activity is an important strategy fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cf2455a7b136a2e0665fb30ea7f35f
https://doi.org/10.1007/s00216-022-04220-2
https://doi.org/10.1007/s00216-022-04220-2
Autor:
Roberto Gaetani, Christopher Yin, Neha Srikumar, Rebecca Braden, Pieter A. Doevendans, Joost P. G. Sluijter, Karen L. Christman
Publikováno v:
Cell Transplantation, Vol 25 (2016)
The use of biomaterials has been demonstrated as a viable strategy to promote cell survival and cardiac repair. However, limitations on combinational cell–biomaterial therapies exist, as cellular behavior is influenced by the microenvironment and p
Externí odkaz:
https://doaj.org/article/e49a44a73b49460ab87ce1bcf18f01a1
Autor:
Neha Srikumar, Joseph Carver, Christoph Spiess, John C. Tran, Ambrose Williams, Yichin Liu, Amy Shen, Phillip Y. Chu, Cong Wu, Ankai Xu, William S. Sawyer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance While electrospray ionization–mass spectrometry (ESI-MS) provides higher resolution for larger proteins, the conventional liquid chromatography (LC)-MS method suffers from low throughput. Our described RapidFire-MS workflow demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842c2cdb134e11180cf936e2e39f7186
https://doi.org/10.1073/pnas.1917383117
https://doi.org/10.1073/pnas.1917383117
Autor:
Robert Tchelepi, John C. Tran, William F. Forrest, Greg A. Lazar, Neha Srikumar, Yichin Liu, Wenjing Li, Chen Gu, Diego Ellerman
Publikováno v:
Analytical chemistry. 92(10)
There are many pharmacokinetic challenges associated with administering protein therapeutics, including biotransformation via clipping, deamidation, isomerization, oxidation, etc. In the case of engineered multivalent tethered antibody formats, prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec90ccf3093af52c614862aeaa95536
https://pubmed.ncbi.nlm.nih.gov/32309925
https://pubmed.ncbi.nlm.nih.gov/32309925
Autor:
Neha Srikumar, Aimee Fourie-O'Donohue, Yichin Liu, John C. Tran, Phillip Y. Chu, Katherine R. Kozak, Ke Sherry Li
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29:1532-1537
Antibody-drug conjugates (ADCs) present unique challenges for ligand-binding assays primarily due to the dynamic changes of the drug-to-antibody ratio (DAR) distribution in vivo and in vitro. Here, an automated on-tip affinity capture platform with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc42a5b23dbd7bfc504137ab7849436
https://doi.org/10.1007/s13361-018-1961-7
https://doi.org/10.1007/s13361-018-1961-7
Autor:
Pieter A. Doevendans, Christopher Yin, Roberto Gaetani, Rebecca L. Braden, Neha Srikumar, Karen L. Christman, Joost P.G. Sluijter
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Cell Transplantation, 25(9), 1653. Cognizant Communication Corporation
Cell Transplantation, 25(9), 1653. Cognizant Communication Corporation
The use of biomaterials has been demonstrated as a viable strategy to promote cell survival and cardiac repair. However, limitations on combinational cell–biomaterial therapies exist, as cellular behavior is influenced by the microenvironment and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445ba5966dc332cfac68849676b98f18
https://doi.org/10.3727/096368915x689794
https://doi.org/10.3727/096368915x689794