Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Negin Iranfar"'
Autor:
Negin Iranfar, Tyler C. Smith
Publikováno v:
Preventing Chronic Disease
INTRODUCTION Estimates indicate that 86 million people in the United States fit the clinical definition of prediabetes, which contributes to the epidemic of nearly 2 million new diagnoses of type 2 diabetes mellitus each year. Effort has focused on p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742e490aaffc4031d76aeae935e2c655
https://pubmed.ncbi.nlm.nih.gov/29565786
https://pubmed.ncbi.nlm.nih.gov/29565786
Publikováno v:
Differentiation. 76:1093-1103
When nutrients are depleted, Dictyostelium cells undergo cell cycle arrest and initiate a differentiation program for survival. We have found a novel gene, srsA, which is rapidly expressed in the first 5 min following the removal of nutrients and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d878e5fc72b3826362edc1eddb82b48d
https://doi.org/10.1111/j.1432-0436.2008.00298.x
https://doi.org/10.1111/j.1432-0436.2008.00298.x
Autor:
Thomas Winckler, Oliver Siol, Unha Baik, Peter Beck, Theodor Dingermann, Ingo Jennes, Negin Iranfar, William F. Loomis
Publikováno v:
Eukaryotic Cell. 3:1349-1358
We recently isolated from Dictyostelium discoideum cells a DNA-binding protein, CbfA, that interacts in vitro with a regulatory element in retrotransposon TRE5-A. We have generated a mutant strain that expresses CbfA at D. discoideum cell physiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64ccb89c25bce6a0aff15f3a48ab601
https://doi.org/10.1128/ec.3.5.1349-1358.2004
https://doi.org/10.1128/ec.3.5.1349-1358.2004
Autor:
Gerald Weeks, Deborah Wessels, Rebecca Brincks, Spencer Kuhl, Vesna Stepanovic, William F. Loomis, Danny Fuller, Negin Iranfar, David R. Soll, George B. Spiegelman, Karla J. Daniels, Chinten James Lim
Publikováno v:
Eukaryotic Cell. 3:646-662
To define the role that RasC plays in motility and chemotaxis, the behavior of a rasC null mutant, rasC − , in buffer and in response to the individual spatial, temporal, and concentration components of a natural cyclic AMP (cAMP) wave was analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2006c9b3e9c097689003ab19e4ce6d65
https://doi.org/10.1128/ec.3.3.646-662.2004
https://doi.org/10.1128/ec.3.3.646-662.2004
Publikováno v:
Eukaryotic Cell. 2:664-670
Using genome-wide microarrays, we recognized 172 genes that are highly expressed at one stage or another during multicellular development of Dictyostelium discoideum . When developed in shaken suspension, 125 of these genes were expressed if the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda7c7ea0f3db26e74cf86cb3ac723ee
https://doi.org/10.1128/ec.2.4.664-670.2003
https://doi.org/10.1128/ec.2.4.664-670.2003
Publikováno v:
Bioinformatics. 18:61-66
Motivation: The DNA microarray technology can generate a large amount of data describing the time-course of gene expression. These data, when properly interpreted, can yield a great deal of information concerning differential gene expression during d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1bcf6d0c5c0d584796e7946c5ad08b
https://doi.org/10.1093/bioinformatics/18.1.61
https://doi.org/10.1093/bioinformatics/18.1.61
Publikováno v:
Proceedings of the National Academy of Sciences. 97:2391-2396
Cellulose is a major component of the extracellular matrices formed during development of the social amoeba, Dictyostelium discoideum . We isolated insertional mutants that failed to accumulate cellulose and had no cellulose synthase activity at any
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77216b035c5ea75061d92ad1f036f68
https://doi.org/10.1073/pnas.040565697
https://doi.org/10.1073/pnas.040565697
Autor:
Danny Fuller, Negin Iranfar, K. Panneerselvam, Marion Lammertz, Hudson H. Freeze, William F. Loomis
Publikováno v:
Developmental Genetics. 21:177-186
We have identified and disrupted the gene coding for α-glucosidase II in Dictyostelium discoideum. This enzyme is responsible for removing two α1,3-linked glucose residues from N-linked oligosaccharides on newly synthesized glycoproteins. Mutagenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4951c10faa14f9a4c8f3601e6f1fada
https://doi.org/10.1002/(sici)1520-6408(1997)21:3<177::aid-dvg1>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1997)21:3<177::aid-dvg1>3.0.co
Publikováno v:
Developmental biology. 290(2)
Expression profiles of developmental genes in Dictyostelium were determined on microarrays during development of wild type cells and mutant cells lacking either the DNA binding protein GBF or the signaling protein LagC. We found that the mutant strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fdd689e1ea57a41163de5e59d99039
https://pubmed.ncbi.nlm.nih.gov/16386729
https://pubmed.ncbi.nlm.nih.gov/16386729
Autor:
Nan Tang, Richard A. Firtel, Negin Iranfar, Hui Ma, William F. Loomis, Fei Du, Michelle C. Mendoza
MEK/extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase signaling is imperative for proper chemotaxis. Dictyostelium mek1(-) (MEK1 null) and erk1(-) cells exhibit severe defects in cell polarization and directional movement,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c950707aa41496ac9788658dd4e1dd
https://europepmc.org/articles/PMC1190274/
https://europepmc.org/articles/PMC1190274/
