Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe.

Autor: Burkhart Colorado AS; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Lazzaro A; Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185, Rome, Italy., Neff CP; Department Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Nusbacher N; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Boyd K; Department of Clinical Research, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, England., Fiorillo S; Department Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Martin C; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Siebert JC; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Campbell TB; Department Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Borok M; Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe., Palmer BE; Department Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. BRENT.PALMER@CUANSCHUTZ.EDU., Lozupone C; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. Catherine.lozupone@cuanschutz.edu.

Publikováno v: Microbiome [Microbiome] 2024 Feb 03; Vol. 12 (1), pp. 18. Date of Electronic Publication: 2024 Feb 03.

Antiretroviral treatment is less effective at reducing gut microbiome-associated inflammation and T cell activation in people living with HIV in rural versus urban Zimbabwe.

Autor: Lazzaro A; Sapienza University of Rome., Colorado ASB; University of Colorado Anschutz Medical Campus., Neff CP; University of Colorado Anschutz Medical Campus., Nusbacher N; University of Colorado Anschutz Medical Campus., Boyd K; London School of Hygiene & Tropical Medicine., Fiorillo S; University of Colorado Anschutz Medical Campus., Martin C; University of Colorado Anschutz Medical Campus., Siebert J; University of Colorado Anschutz Medical Campus., Campbell T; University of Colorado Anschutz Medical Campus., Borok M; University of Zimbabwe., Palmer B; University of Colorado Anschutz Medical Campus., Lozupone C; University of Colorado Anschutz Medical Campus.

Publikováno v: Research square [Res Sq] 2023 Aug 31. Date of Electronic Publication: 2023 Aug 31.

Nucleocapsid protein binding DNA aptamers for detection of SARS-COV-2.

Autor: Neff CP; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Cikara M; Precision Medicine Architects, LLC, PO Box 148, Wellington, CO 80549, United States., Geiss BJ; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA., Thomas Caltagirone G; Aptagen, LLC, 250 North Main Street, Jacobus, PA 17407, USA., Liao A; Aptagen, LLC, 250 North Main Street, Jacobus, PA 17407, USA., Atif SM; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Macdonald B; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Schaden R; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Publikováno v: Current research in biotechnology [Curr Res Biotechnol] 2023; Vol. 5, pp. 100132. Date of Electronic Publication: 2023 May 27.

SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2.

Autor: Littlefield KM; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Watson RO; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Schneider JM; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Neff CP; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Yamada E; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Zhang M; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Campbell TB; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Falta MT; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Jolley SE; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Fontenot AP; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Palmer BE; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2022 May 26; Vol. 18 (5), pp. e1010359. Date of Electronic Publication: 2022 May 26 (Print Publication: 2022).

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.

Autor: Tengesdal IW; Department of Medicine, University of Colorado Denver, Aurora, CO 80045.; Department of Internal Medicine, Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Menon DR; Department of Dermatology, University of Colorado Denver, Aurora, CO 80045., Osborne DG; Department of Dermatology, University of Colorado Denver, Aurora, CO 80045., Neff CP; Department of Medicine, University of Colorado Denver, Aurora, CO 80045., Powers NE; Department of Medicine, University of Colorado Denver, Aurora, CO 80045., Gamboni F; Department of Medicine, University of Colorado Denver, Aurora, CO 80045., Mauro AG; Virginia Commonwealth University Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23230., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045., Stefanoni D; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045., Henen MA; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045.; Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Mills TS; Division of Hematology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045., De Graaf DM; Department of Medicine, University of Colorado Denver, Aurora, CO 80045.; Department of Internal Medicine, Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Azam T; Department of Medicine, University of Colorado Denver, Aurora, CO 80045., Vogeli B; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO 80045., Palmer BE; Department of Medicine, University of Colorado Denver, Aurora, CO 80045., Pietras EM; Division of Hematology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045., DeGregori J; Virginia Commonwealth University Pauley Heart Center, Virginia Commonwealth University, Richmond, VA 23230., Tan AC; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL 33612., Joosten LAB; Department of Internal Medicine, Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Fujita M; Department of Dermatology, University of Colorado Denver, Aurora, CO 80045; mayumi.fujita@cuanschutz.edu cdinare333@aol.com carlo.marchetti@cuanschutz.edu., Dinarello CA; Department of Medicine, University of Colorado Denver, Aurora, CO 80045; mayumi.fujita@cuanschutz.edu cdinare333@aol.com carlo.marchetti@cuanschutz.edu.; Department of Internal Medicine, Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Marchetti C; Department of Medicine, University of Colorado Denver, Aurora, CO 80045; mayumi.fujita@cuanschutz.edu cdinare333@aol.com carlo.marchetti@cuanschutz.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 09; Vol. 118 (10).