Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nefeli Batistatou"'
Autor:
Hawley Brown, Mia Chung, Alina Üffing, Nefeli Batistatou, Tiffany Tsang, Samantha Doskocil, Weiqun Mao, Dieter Willbold, Robert C. Bast, Zhen Lu, Oliver H. Weiergräber, Joshua A. Kritzer
Publikováno v:
Journal of the American Chemical Society. 144(32)
The LC3/GABARAP family of proteins is involved in nearly every stage of autophagy. Inhibition of LC3/GABARAP proteins is a promising approach to blocking autophagy, which sensitizes advanced cancers to DNA-damaging chemotherapy. Here, we report the s
Autor:
Nefeli Batistatou, Joshua A. Kritzer
Publikováno v:
ChemBioChem. 24
Autor:
Kirsten Deprey, Nefeli Batistatou, Marjoke F. Debets, Jack Godfrey, Kirstin B. VanderWall, Rebecca R. Miles, Livia Shehaj, Jiaxing Guo, Amy Andreucci, Pachamuthu Kandasamy, Genliang Lu, Mamoru Shimizu, Chandra Vargeese, Joshua A. Kritzer
Publikováno v:
ACS Chem Biol
A major obstacle to the development of effective oligonucleotide therapeutics is a lack of understanding about their cytosolic and nuclear penetration. To address this problem, we have applied the chloroalkane penetration assay (CAPA) to oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca7a1a52699e0b7e5fa1b2efc41faf6
https://europepmc.org/articles/PMC9252293/
https://europepmc.org/articles/PMC9252293/
Publikováno v:
Nucleic Acids Research
RNA therapeutics are a promising strategy to treat genetic diseases caused by the overexpression or aberrant splicing of a specific protein. The field has seen major strides in the clinical efficacy of this class of molecules, largely due to chemical
Autor:
Seth T. Gammon, Jing Wang, Hailing Yang, Philip Rask, Robert C. Bast, Margie N. Sutton, Joshua A. Kritzer, David Piwnica-Worms, Zhen Lu, Brian J. Engel, Joshua P. Gray, Nasir Uddin, Brian J. Grindel, Shuxing Zhang, Hannah Locke, Pratip K. Bhattacharya, Nefeli Batistatou, Rajan Chaudhari, Steven W. Millward
Publikováno v:
Chemical Science
In recent decades it has become increasingly clear that induction of autophagy plays an important role in the development of treatment resistance and dormancy in many cancer types. Unfortunately, chloroquine (CQ) and hydroxychloroquine (HCQ), two aut