Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Neeta Khandekar"'
Autor:
Que T. La, Binhai Ren, Grant J. Logan, Sharon C. Cunningham, Neeta Khandekar, Najah T. Nassif, Bronwyn A. O’Brien, Ian E. Alexander, Ann M. Simpson
Publikováno v:
Cells, Vol 9, Iss 10, p 2227 (2020)
Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of
Externí odkaz:
https://doaj.org/article/f8c03c105c804188a1339d6c7227bb54
Autor:
Grant J. Logan, Mario Mietzsch, Neeta Khandekar, Arlene D’Silva, Daniel Anderson, Mawj Mandwie, Jane Hsi, Austin R. Nelson, Paul Chipman, Jennifer Jackson, Peter Schofield, Daniel Christ, Christopher C. Goodnow, Joanne H. Reed, Michelle A. Farrar, Robert McKenna, Ian E. Alexander
Publikováno v:
Molecular Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e2ebae53db06f725e5eceb4546372bc
https://doi.org/10.1016/j.ymthe.2023.03.032
https://doi.org/10.1016/j.ymthe.2023.03.032
Autor:
Bronwyn A. O'Brien, Grant J Logan, Ann M. Simpson, Binhai Ren, Que T. La, Najah T. Nassif, Ian E. Alexander, Neeta Khandekar, Sharon C. Cunningham
Publikováno v:
Cells
Volume 9
Issue 10
Cells, Vol 9, Iss 2227, p 2227 (2020)
Volume 9
Issue 10
Cells, Vol 9, Iss 2227, p 2227 (2020)
Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b789776a37fe8ea3fcc17f4eaa866eb
Publikováno v:
International Journal of Medical Sciences
The receptor activator of nuclear factor-κB ligand (RANKL) modulates energy metabolism. However, how RANKL regulates energy homeostasis is still not clear. This study aims to investigate the central mechanisms by which central administration of RANK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82505c9460f7b2212be1d0f7f09c1691
http://europepmc.org/articles/PMC6036154
http://europepmc.org/articles/PMC6036154
Autor:
He Yang, Wan-Ru Wang, Shu Lin, Yilian Zhang, Neeta Khandekar, Shan-Wen Zhang, Shi-Fei Tong, Xu-Feng Huang, Zhiyuan Song
Publikováno v:
Endocrine. 56:65-72
The estrogen levels in the pre and post menstrual phases interact with brain-derived neurotrophic factor in a complex manner, which influences the overall state of the body. To study the role of oestradiol and brain-derived neurotrophic factor in mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1936098051b1d694cf2310998f12f1b
https://doi.org/10.1007/s12020-016-1197-x
https://doi.org/10.1007/s12020-016-1197-x
Autor:
Sharon C. Cunningham, Bronwyn A. O'Brien, Grant J Logan, Binhai Ren, Ann M. Simpson, Najah T. Nassif, Ian E. Alexander, Neeta Khandekar, Que T. La
Publikováno v:
Diabetes. 68
Previously we introduced furin-cleavable human insulin (INSFUR) to the livers in several animal models using a lentiviral vector. Reversal of diabetes with normal glucose tolerance and pancreatic transdifferentiation was seen. The aim of the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9bd7ec967e1ac9b4460dd85fb54803a
https://doi.org/10.2337/db19-1778-p
https://doi.org/10.2337/db19-1778-p
Publikováno v:
Molecular and Cellular Endocrinology. 418:33-41
Imbalances in normal regulation of food intake can cause obesity and related disorders. Inadequate therapies for such disorders necessitate better understanding of mechanisms that regulate energy homeostasis. Pancreatic polypeptide (PP), a robust ano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9791f8a80fe47527e62ae89ee9ba09
https://doi.org/10.1016/j.mce.2015.06.028
https://doi.org/10.1016/j.mce.2015.06.028
Autor:
Shi‑Yu Liang, Zhihui Zhang, Xu-Feng Huang, Shu Lin, Zhi‑Yuan Song, Neeta Khandekar, Yan-Chuan Shi, Ping Zhu, He‑Qin Yang
Publikováno v:
Molecular Medicine Reports
Cold exposure is considered to be a form of stress and has various adverse effects on the body. The present study aimed to investigate the effects of chronic daily cold exposure on food intake, body weight, serum glucose levels and the central energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d4128e84f7b8969507e70323c8dd47
https://doi.org/10.3892/mmr.2018.9382
https://doi.org/10.3892/mmr.2018.9382
Autor:
Emilie E. Wilkie, Christine M. Smyth, Grant J Logan, Claus V. Hallwirth, Anais K. Amaya, Neeta Khandekar, Sophia H.Y. Liao, Allison P Dane, Leszek Lisowski, Sharon C. Cunningham, David W. Russell, Patrick P.L. Tam, Marti Cabanes-Creus, Ian E. Alexander, Samantha L. Ginn, Erhua Zhu, Natsuki Sasaki
Publikováno v:
Nature genetics. 49(8)
Vectors based on adeno-associated virus type 2 (AAV2) are powerful tools for gene transfer and genome editing applications. The level of interest in this system has recently surged in response to reports of therapeutic efficacy in human clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89c42d12f92cc091f041a3d030cec81
https://pubmed.ncbi.nlm.nih.gov/28628105
https://pubmed.ncbi.nlm.nih.gov/28628105
Publikováno v:
Stem Cells and Development. 21:997-1006
Alzheimer's disease (AD) is a leading cause of age-related dementia that is characterized by an extensive loss of neurons and synaptic transmission. The pathological hallmarks of AD are neurofibrillary tangles and deposition of β-amyloid (Aβ) plaqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c2595369043b22a34f38b1642c5035
https://doi.org/10.1089/scd.2011.0564
https://doi.org/10.1089/scd.2011.0564