Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model.

Autor: Boecker, Arne Hendrik¹, Neerven, Sabien Geraldine Antonia¹, Scheffel, Juliane¹, Tank, Julian¹, Altinova, Haktan^2,3, Seidensticker, Katrin⁴, Deumens, Ronald^2,5, Tolba, Rene⁶, Weis, Joachim^2,7, Brook, Gary Anthony^2,7, Pallua, Norbert¹, Bozkurt, Ahmet^1,8, Mallucci, Giovanna

Publikováno v: European Journal of Neuroscience. Feb2016, Vol. 43 Issue 3, p404-416. 13p. 5 Color Photographs, 1 Diagram, 1 Chart, 5 Graphs.

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Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix.

Autor: Boecker AH; Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany.; Department of Hand-Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen, University of Heidelberg, Ludwigshafen, Germany., Bozkurt A; Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany.; Department of Plastic, Hand, Reconstructive and Aesthetic Surgery, Helios Klinikum Wuppertal, University Witten/Herdecke, Wuppertal, Germany., Kim BS; Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany., Altinova H; Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.; Institute of Neuropathology, University Hospital RWTH Aachen, Aachen, Germany., Tank J; Department of General, Visceral and Thoracic Surgery, Private Medical University, Nuremberg, Germany., Deumens R; Neuropharmacology, Université Catholique de Louvain, Brussels, Belgium.; Institute of Neuropathology, University Hospital RWTH Aachen, Aachen, Germany., Tolba R; Institute for Laboratory Animal Research, University Hospital RWTH Aachen, Aachen, Germany., Weis J; Institute of Neuropathology, University Hospital RWTH Aachen, Aachen, Germany.; Translational Brain Medicine (JARA Brain), Juelich-Aachen Research Alliance, Germany., Brook GA; Institute of Neuropathology, University Hospital RWTH Aachen, Aachen, Germany.; Translational Brain Medicine (JARA Brain), Juelich-Aachen Research Alliance, Germany., Pallua N; Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany., van Neerven SGA; Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany.

Publikováno v: Journal of tissue engineering and regenerative medicine [J Tissue Eng Regen Med] 2018 Nov; Vol. 12 (11), pp. 2125-2137. Date of Electronic Publication: 2018 Sep 12.