Výsledky vyhledávání - "Neerja Yadav-Bhatnagar"

MALDI-TOF MS analysis of soluble PEG based multi-step synthetic reaction mixtures with automated detection of reaction failure

Autor: Jean-Louis Aubagnac, Neerja Yadav-Bhatnagar, Jean Martinez, Frédéric Lamaty, Patrice Ribière, Christine Enjalbal

Publikováno v: Journal of The American Society for Mass Spectrometry
Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2005, 16, pp.670-678. ⟨10.1016/j.jasmas.2005.01.020⟩

Macromolecules of tunable solubility, used to mimic inert insoluble materials while maintaining solution conditions, allowed the performance of efficient supported organic chemistry and facilitated in situ reaction monitoring. To satisfy the high thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f4554adfdbebe21d1d0483fdd5c231
https://doi.org/10.1016/j.jasms.2005.01.020

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Preparation of Poly(Ethylene Glycol) Sulfonamide: Synthesis of N-Supported β-Aminoesters via the Aza-Baylis−Hillman Reaction

Autor: Jean-Louis Aubagnac, Neerja Yadav-Bhatnagar, Patrice Ribière, Christine Enjalbal, Frédéric Lamaty, Jean Martinez

Publikováno v: Journal of Combinatorial Chemistry
Journal of Combinatorial Chemistry, American Chemical Society, 2004, 6, pp.467. ⟨10.1021/cc049966n⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f025eb5f6a8046195ec1cac1662e6beb
https://doi.org/10.1021/cc049966n

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Characterization of Soluble Polymer Supported Organic Compounds by LC/Electrospray Ionization MS Toward a Complete Automation of the Liquid-Phase Process in Combinatorial Chemistry

Autor: R. Lazaro, Frédéric Lamaty, Neerja Yadav-Bhatnagar, and J. Martinez, S. Varray, † J.-L. Aubagnac, P. Sanchez, P. Ribière, E. Suberchicot, Christine Enjalbal

Publikováno v: Analytical Chemistry. 75:175-184

In the case of a soluble polymer supported synthesis, the tuning of the support solubility depending on the solvent offers new opportunities for combinatorial chemistry for two reasons. First, organic syntheses in solution are generally easily transl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570c15867668267f318bf4d6ed1528f8
https://doi.org/10.1021/ac0203701

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Polymer-Supported Approach for Solution-Phase Synthesis of Cysteine Trap Protease Inhibitors: Procedure for Straightforward Optimization of the P1−P1‘ Pocket

Autor: and Nicolas Desjonquères, Jacques Mauger, Neerja Yadav-Bhatnagar

Publikováno v: Journal of Combinatorial Chemistry. 4:49-55

Peptide-based reversible and irreversible cysteine proteases inhibitors are well reported in the literature. Many of these compounds have an electrophilic carbonyl group as a cysteine trap in the place of a scissile amide moiety of the natural substr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d681809f6708783dc0f5d6123b82b0
https://doi.org/10.1021/cc010037v

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Synthesis of the Imidazole-Derived AT1-Selective ANG II Receptor Antagonist HR 720 Utilizing Reductive Amination as Key Step

Autor: Neerja Yadav-Bhatnagar, Wagner Adalbert, Christine Griffoul-Marteau, Holger Heitsch

Publikováno v: Synthesis. 1996:1325-1330

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbe92b6ec34d515b89ebe4eaf94cfef1
https://doi.org/10.1055/s-1996-4383

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ChemInform Abstract: Synthesis of the Imidazole-Derived AT1-Selective ANG II Receptor Antagonist HR 720 Utilizing Reductive Amination as Key Step

Autor: Christine Griffoul-Marteau, Neerja Yadav-Bhatnagar, Wagner Adalbert, Holger Heitsch

Publikováno v: ChemInform. 28

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fccc1fe0e6b0667b3c13f478d3171f2
https://doi.org/10.1002/chin.199715132

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Synthesis of novel poly(ethylene glycol) supported benzazepines, the crucial role of PEG on the selectivity of an intramolecular Heck reaction

Autor: Jean Martinez, Yannig Nedellec, Valérie Declerck, Frédéric Lamaty, Patrice Ribière, Neerja Yadav-Bhatnagar

Publikováno v: Tetrahedron
Tetrahedron, Elsevier, 2006, 62, pp.10456-10466. ⟨10.1016/j.tet.2006.08.009⟩

Poly(ethylene glycol) (PEG 3400) was used as a soluble polymeric support for the synthesis of a series of novel benzazepines. The key step for the preparation of these heterocycles was a phosphine-free palladium-catalyzed Heck reaction. Palladium nan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8334affd403f88835c64374299eccd73
https://hal.archives-ouvertes.fr/hal-00377333

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Microwave-assisted aza-Baylis-Hillman reaction. Preparation of poly(ethylene glycol) supported a-methylene-ß-aminoester

Autor: Frédéric Lamaty, Neerja Yadav-Bhatnagar, Jean Martinez, Patrice Ribière

Publikováno v: QSAR & Combinatorial Science
QSAR & Combinatorial Science, 2004, 23, pp.914. ⟨10.1002/qsar.200420041⟩

The aza-Baylis Hillman is a practical method for the preparation of a-methylene-β-aminoesters. A soluble polymer supported version of this reaction has been developed. The reaction was shown to proceed in the absence of solvent under microwave activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977a6f344bd0561b7a6acb60c03578a2
https://hal.archives-ouvertes.fr/hal-00077979

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