Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Neeraja P. Alamuru-Yellapragada"'
Autor:
Kishore V.L. Parsa, Bandish Kapadia, Jagadheshan Hiriyan, Prasad Shivarudraiah, Phanithi Prakash Babu, Vasundhara Kain, Neeraja P. Alamuru-Yellapragada, Soma Behera, Parimal Misra, Narmadha Reddy Gangula, Vachana Murunikkara, Sriram Seshadri, Subbareddy Maddika, Sireesh T. Kumar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:1702-1716
Nutritional abundance associated with chronic inflammation and dyslipidemia impairs the functioning of endoplasmic reticulum (ER) thereby hampering cellular responses to insulin. PHLPP1 was identified as a phosphatase which inactivates Akt, the maste
Publikováno v:
Biochemical and Biophysical Research Communications. 487:247-254
Electroporation is the most widely employed method of gene transfer into macrophages which are hard to transfect. RAW 264.7 is a widely used cell line for studying macrophage responses. Electroporation of RAW 264.7 cells with commercial reagents alth
Publikováno v:
Biochemical and Biophysical Research Communications. 486:533-538
We have previously reported that bacterial endotoxin LPS attenuates expression of PHLPP, a ser/thr phosphatase, at both transcript and protein levels in different immune cells, however the underlying molecular mechanism is unknown and is of significa
Publikováno v:
Biochemical and biophysical research communications. 483(1)
Post translational modifications, ubiquitination and its reversal by deubiquitination play an important role in regulating innate immune system. USP12 is a poorly studied deubiquitinase reported to regulate T-cell receptor signalling however the func