Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Neeraja Dharmaraj"'
Autor:
Minh Phuong Dong, Neeraja Dharmaraj, Estela Kaminagakura, Jianfei Xue, David G. Leach, Jeffrey D. Hartgerink, Michael Zhang, Hana-Joy Hanks, Yi Ye, Bradley E. Aouizerat, Kyle Vining, Carissa M. Thomas, Sinisa Dovat, Simon Young, Chi T. Viet
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 920 (2024)
Oral squamous cell carcinoma (OSCC) presents significant treatment challenges due to its poor survival and intense pain at the primary cancer site. Cancer pain is debilitating, contributes to diminished quality of life, and causes opioid tolerance. T
Externí odkaz:
https://doaj.org/article/6e08a52ce46a4c4ebfc4aafaca817580
Autor:
Jared M. Newton, Aurelie Hanoteau, Hsuan-Chen Liu, Angelina Gaspero, Falguni Parikh, Robyn D. Gartrell-Corrado, Thomas D. Hart, Damya Laoui, Jo A. Van Ginderachter, Neeraja Dharmaraj, William C. Spanos, Yvonne Saenger, Simon Young, Andrew G. Sikora
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-21 (2019)
Abstract Background Immune checkpoint inhibitors (ICIs) for solid tumors, including those targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), have shown impressive clinical efficacy, however, most patien
Externí odkaz:
https://doaj.org/article/5865ba33af83434c8d59aa844ab92960
Autor:
Neeraja Dharmaraj, Stacey L. Piotrowski, Chen Huang, Jared M. Newton, Leonard S. Golfman, Aurelie Hanoteau, Sandeep T. Koshy, Aileen W. Li, Merlyn X. Pulikkathara, Bing Zhang, Jared K. Burks, David J. Mooney, Yu L. Lei, Andrew G. Sikora, Simon Young
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Immunotherapeutic treatments in head and neck cancer clinical trials include cancer vaccines targeting foreign viral antigens or mutational neoantigens derived from cancer-expressed proteins. Anti-tumor immune responses place cancer cells under selec
Externí odkaz:
https://doaj.org/article/f335e36ae8624751bbcd1391c7cf9e06
Autor:
Tania L. Lopez-Silva, Simon Young, Jeffrey D. Hartgerink, David G. Leach, Brett H Pogostin, Jose Rodriguez Venzor, Neeraja Dharmaraj, Andrew G. Sikora
Publikováno v:
ACS Biomater Sci Eng
We evaluated a peptide-based immunotherapy termed SynerGel: an injectable, biomaterial-based platform for intratumoral drug delivery. A drug-mimicking peptide hydrogel named L-NIL-MDP was loaded with an antitumor cyclic dinucleotide (CDN) immunothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a2c24b54ba97e8f72334f07cddff9
https://pubmed.ncbi.nlm.nih.gov/33470801
https://pubmed.ncbi.nlm.nih.gov/33470801
Publikováno v:
Encyclopedia of Biological Chemistry III ISBN: 9780128220405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff6cadbb2097fed2a996e9b6e45aa846
https://doi.org/10.1016/b978-0-12-819460-7.00214-0
https://doi.org/10.1016/b978-0-12-819460-7.00214-0
Autor:
Simon Young, Jared K. Burks, David J. Mooney, Aurelie Hanoteau, Yu Lei, Neeraja Dharmaraj, Jared M. Newton, Stacey L. Piotrowski, Andrew G. Sikora, Merlyn Pulikkathara, Chen Huang, Aileen W. Li, Sandeep T. Koshy, Bing Zhang, Leonard Golfman
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Immunotherapeutic treatments in head and neck cancer clinical trials include cancer vaccines targeting foreign viral antigens or mutational neoantigens derived from cancer-expressed proteins. Anti-tumor immune responses place cancer cells under selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5beef0f565e1c548503be8791cda7a28
https://doaj.org/article/f335e36ae8624751bbcd1391c7cf9e06
https://doaj.org/article/f335e36ae8624751bbcd1391c7cf9e06
Autor:
Newton, Jared, Hanoteau, Aurelie, Hsuan-Chen Liu, Gaspero, Angelina, Falguni Parikh, Gartrell-Corrado, Robyn, Hart, Thomas, Damya Laoui, Ginderachter, Jo, Neeraja Dharmaraj, Spanos, William, Saenger, Yvonne, Young, Simon, Sikora, Andrew
Figure S2. Individual tumor growth curves for singlet and dual treatments and CTX/L-NIL gene expression. Subcutaneous established mEER tumors (day 17–18 post tumor cell injection) were treated with individual or dual treatment combinations of PD-1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c838eaa1060ea8e406fafa27284a6ab
Autor:
Newton, Jared, Hanoteau, Aurelie, Hsuan-Chen Liu, Gaspero, Angelina, Falguni Parikh, Gartrell-Corrado, Robyn, Hart, Thomas, Damya Laoui, Ginderachter, Jo, Neeraja Dharmaraj, Spanos, William, Saenger, Yvonne, Young, Simon, Sikora, Andrew
Figure S12. Lymphoid flow cytometry gating strategies. Flow cytometry strategy used for gating lymphoid subsets, with labeled cell type above the respective gate. (A) T cell phenotype panel which included various markers to assess T cell memory, acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720d297f340160d8c048f780f478280d
Publikováno v:
Expert review of endocrinologymetabolism. 3(4)
MUC1 is a multifunctional cell surface glycoprotein that modulates cell adhesion, protects mucosa from infection and enzymatic attack, lubricates cell surfaces, participates in multiple signal-transduction pathways and is overexpressed by many tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f33e040d6d0bfcd63426d2357599f7
https://pubmed.ncbi.nlm.nih.gov/30290438
https://pubmed.ncbi.nlm.nih.gov/30290438
Autor:
Jeffrey D. Hartgerink, Andrew G. Sikora, David G. Leach, Tania L. Lopez-Silva, Yu Lei, Simon Young, Stacey L. Piotrowski, Neeraja Dharmaraj
Recent advancements in the field of immunotherapy have yielded encouraging results for the treatment of advanced cancers. Cyclic dinucleotides (CDNs) are a powerful new class of immunotherapy drugs known as STING (Stimulator of Interferon Genes) agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e193c352e6e7fb8e569bc9db9e87417
https://europepmc.org/articles/PMC5840037/
https://europepmc.org/articles/PMC5840037/