Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Neeraja, Purandare"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b1aa4d2f6111438a98b4dd852a68136d
Publikováno v:
Viruses, Vol 15, Iss 12, p 2380 (2023)
Mitochondria have been identified as the “powerhouse” of the cell, generating the cellular energy, ATP, for almost seven decades. Research over time has uncovered a multifaceted role of the mitochondrion in processes such as cellular stress signa
Externí odkaz:
https://doaj.org/article/93497b0594af46a9b3190ddcc2b0ea2a
Autor:
Hussein Chehade, Neeraja Purandare, Alexandra Fox, Nicholas Adzibolosu, Shawn Jayee, Aryan Singh, Roslyn Tedja, Radhika Gogoi, Siddhesh Aras, Lawrence I. Grossman, Gil Mor, Ayesha B. Alvero
Publikováno v:
Translational Oncology, Vol 29, Iss , Pp 101623- (2023)
Cancer progression requires the acquisition of mechanisms that support proliferative potential and metastatic capacity. MNRR1 (also CHCHD2, PARK22, AAG10) is a bi-organellar protein that in the mitochondria can bind to Bcl-xL to enhance its anti-apop
Externí odkaz:
https://doaj.org/article/89a8bc8b63a84bbfb5fbfc3aa920eddc
Autor:
Harpreet Kaur, Paige Minchella, David Alvarez-Carbonell, Neeraja Purandare, Vijay K. Nagampalli, Daniel Blankenberg, Todd Hulgan, Mariana Gerschenson, Jonathan Karn, Siddhesh Aras, Asha R. Kallianpur
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12242 (2023)
HIV-associated cognitive dysfunction during combination antiretroviral therapy (cART) involves mitochondrial dysfunction, but the impact of contemporary cART on chronic metabolic changes in the brain and in latent HIV infection is unclear. We interro
Externí odkaz:
https://doaj.org/article/2c92077cfce847e5aeeb5e45b0b98d7d
Autor:
Neeraja Purandare, Yusef Kunji, Yue Xi, Roberto Romero, Nardhy Gomez-Lopez, Andrew Fribley, Lawrence I. Grossman, Siddhesh Aras
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105342- (2022)
Summary: Mitochondria play a key role in placental growth and development, and mitochondrial dysfunction is associated with inflammation in pregnancy pathologies. However, the mechanisms whereby placental mitochondria sense inflammatory signals are u
Externí odkaz:
https://doaj.org/article/4548f7d633da4322b5551fac2a08db3f
Autor:
Neeraja Purandare, Katherine J. Kramer, Paige Minchella, Sarah Ottum, Christopher Walker, Jessica Rausch, Conrad R. Chao, Lawrence I. Grossman, Siddhesh Aras, Maurice-Andre Recanati
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 2, p 301 (2022)
Adhesions frequently occur postoperatively, causing morbidity. In this noninterventional observational cohort study, we enrolled patients who presented for repeat abdominal surgery, after a history of previous abdominal myomectomy, from March 1998 to
Externí odkaz:
https://doaj.org/article/0569bac3d7b440ada00c776841a8a9f6
Autor:
Neeraja Purandare, Nardhy Gomez-Lopez, Marcia Arenas-Hernandez, Jose Galaz, Roberto Romero, Yue Xi, Andrew Fribley, Lawrence I. Grossman, Siddhesh Aras
Intra-amniotic inflammation leading to preterm birth is one of the leading causes of neonatal morbidity and mortality. We recently found that the mitochondrial levels of MNRR1 (Mitochondrial Nuclear Retrograde, Regulator 1; also called CHCHD2, AAG10,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5430f47a0851634f70d816a1c3595700
https://doi.org/10.1101/2023.01.30.525762
https://doi.org/10.1101/2023.01.30.525762
Autor:
Katherine J, Kramer, Neeraja, Purandare, Siddhesh, Aras, Fatemeh, Parsian, Sandra, Sadek, Conrad, Chao, Robert A, Welch, Maurice-Andre, Recanati
Publikováno v:
Journal of Perinatal Medicine. 51:432-434
Objectives Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is involved in the production of fetal lung surfactant. We have shown that LPCAT1 mRNA is present in amniotic fluid and maternal plasma and that its quantity correlates with the amniotic f
Autor:
Katherine J. Kramer, Jordan Zhou, Mallika Somayajulu, Siddhesh Aras, Robert A. Welch, Lawrence I. Grossman, Maurice-Andre Recanati, Paige Minchella, Neeraja Purandare, Nellena Adekoya
Publikováno v:
Placenta
INTRODUCTION: Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) is necessary for surfactant production of in fetal lungs. Mechanisms responsible for its regulation during gestation remain to be elucidated. Our goal is to evaluate molecular mechanism
Autor:
Jessica Dragotto, Siddhesh Aras, Robert P. Erickson, Maria Teresa Fiorenza, Maik Hüttemann, Neeraja Purandare, Lawrence I. Grossman, Jenney Liu
Publikováno v:
Mitochondrion. 51:15-21
It has long been known that there is decreased mitochondrial function in several tissues of Niemann–Pick C1 model mice and cultured cells. These defects contribute to the accumulation of Reactive Oxygen Species (ROS) and tissue damage. It is also w