Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Neeraj Tuladhar"'
Autor:
Abdullah A. Tarique, Neeraj Tuladhar, Dean Kelk, Nelufa Begum, Richard M. Lucas, Lin Luo, Jennifer L. Stow, Claire E. Wainwright, Scott C. Bell, Peter D. Sly, Emmanuelle Fantino
Publikováno v:
Cells, Vol 13, Iss 2, p 166 (2024)
Background: Azithromycin (AZM) is widely being used for treating patients with cystic fibrosis (pwCF) following clinical trials demonstrating improved lung function and fewer incidents of pulmonary exacerba-tions. While the precise mechanisms remain
Externí odkaz:
https://doaj.org/article/ab3ca60e7c704385958293d1d99c96ce
Autor:
Zhijian Xiao, Neeraj Tuladhar, Yvette W. H. Koh, Jennifer L. Stow, Darren L. Brown, Nicholas D. Condon, Yu Hung
Publikováno v:
Journal of visualized experiments : JoVE. (174)
Macropinocytosis is a highly conserved but still incompletely understood process that is essential for the uptake and ingestion of fluid, fluid-phase nutrients and other material in cells. The dramatic extension of cell surface ruffles, their closure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74e7d79ec2c8dce0e6546706338660a
https://pubmed.ncbi.nlm.nih.gov/34424243
https://pubmed.ncbi.nlm.nih.gov/34424243
Autor:
Adam A. Wall, James E. B. Curson, Richard Lucas, Neeraj Tuladhar, Jennifer L. Stow, Lin Luo, Matthew J. Sweet, Liping Liu
Publikováno v:
Journal of Leukocyte Biology. 107:251-262
In innate immune cells, pathogens and danger signals activate TLRs, unleashing potent and tailored inflammatory responses. Previously, we reported that an immune-specific transmembrane adaptor, SLP adaptor and CSK interacting membrane protein (SCIMP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4aed0275ab1eba511b407b22f9db082
https://doi.org/10.1002/jlb.2ma0819-138rr
https://doi.org/10.1002/jlb.2ma0819-138rr
Autor:
Neeraj Tuladhar, Jennifer L. Stow, Zhijian Xiao, Lin Luo, Jana Vukovic, Adam A. Wall, Yu Hung, Samuel J. Tong
To support their innate immune and scavenging functions in the brain, microglia are equipped with Toll-like receptors (TLRs), including the intracellular receptor TLR9, which is activated by microbial CpG-rich DNA. Macropinocytosis is an abundant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c574bccd12e0411172b11ce2744c27
https://doi.org/10.1101/2021.02.11.430773
https://doi.org/10.1101/2021.02.11.430773
Autor:
Liping Liu, Richard M. Lucas, Jeffrey D. Nanson, Yan Li, Jason Whitfield, James E.B. Curson, Neeraj Tuladhar, Kirill Alexandrov, Mehdi Mobli, Matthew J. Sweet, Bostjan Kobe, Jennifer L. Stow, Lin Luo
Publikováno v:
Journal of Biological Chemistry. 298:101857
Innate immune signaling by Toll-like receptors (TLRs) involves receptor phosphorylation, which helps to shape and drive key inflammatory outputs, yet our understanding of the kinases and mechanisms that mediate TLR phosphorylation is incomplete. Sple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8087dc149e81fb4ac04b199d2d03f043
https://doi.org/10.1016/j.jbc.2022.101857
https://doi.org/10.1016/j.jbc.2022.101857
Autor:
Matthew J. Sweet, Richard Lucas, Lin Luo, James E. B. Curson, Kaustav Das Gupta, Yvette W. H. Koh, Nicholas D. Condon, Neeraj Tuladhar, Kate Schroder, Jennifer L. Stow, Liping Liu, Sabrina Sofia Burgener, Evan Ingley
Publikováno v:
Cell Reports. 36:109662
Immune cells are armed with Toll-like receptors (TLRs) for sensing and responding to pathogens and other danger cues. The role of extracellular-signal-regulated kinases 1/2 (Erk1/2) in TLR signaling remains enigmatic, with both pro- and anti-inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82ef18ec6272216e4c0b822fb59cec1
https://doi.org/10.1016/j.celrep.2021.109662
https://doi.org/10.1016/j.celrep.2021.109662