Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Neeraj Masand"'
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 10, Iss , Pp 100133- (2024)
The protein-ligand interactions play critical roles in targeted therapies including viral and cancer therapies. Hence in recent years several experimental and computational methods have been developed to address the mechanism of selectivity, swift bi
Externí odkaz:
https://doaj.org/article/7187a2f4084a43ee8f88bced33fa400f
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 33, Iss 1, Pp 1-16 (2021)
Abstract Background The expression of hERG K+ channels is observed in various cancer cells including epithelial, neuronal, leukemic, and connective tissue. The role of hERG potassium channels in regulating the growth and death of cancer cells include
Externí odkaz:
https://doaj.org/article/0c45d7f460b04441a37f4354bfc95753
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 4, Iss , Pp 100018- (2022)
The well-known anti-helminthic drug ivermectin (IVM) has been established as an example of drug repurposing for the management of SARS-CoV-2 infection. Various study has been done to understand the inhibitory mechanism of IVM against SARS-CoV-2 targe
Externí odkaz:
https://doaj.org/article/347c6ebe849545a099e14ac4247c8b4f
Publikováno v:
Current Topics in Medicinal Chemistry. 22:2207-2220
Abstract: Clinical translation is a challenging step in the development of cancer vaccines and is found to be related to the complex nature of cancer immunology. Vaccine-based therapeutic strategies for cancer have gained consideration with the adven
Publikováno v:
Molecular Diversity. 27:959-985
CNS disorders are indications with a very high unmet medical needs, relatively smaller number of available drugs, and a subpar satisfaction level among patients and caregiver. Discovery of CNS drugs is extremely expensive affair with its own unique c
Publikováno v:
Current Topics in Medicinal Chemistry. 23
Abstract: Natural product substances have historically served as the most significant source of new leads for pharmaceutical development. Presently, drug discovery and development have adopted rational approaches to explore herbal resources for treat
Autor:
Krishnan Balasubramanian, Neeraj Masand, Rameshwar S. Cheke, Rohan R. Narkhede, Vaishali M. Patil
Publikováno v:
Coronaviruses. 2:10-27
Introduction: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is plaguing the entire world. Amidst the pandemic, research and development efforts are focused on the challenges associated with SARSCoV-2 structure. Material an
Publikováno v:
Current Chemical Biology. 15:69-84
Breast cancer is the most common and highly heterogeneous neoplastic disease comprised of several subtypes with distinct molecular etiology and clinical behaviours. The mortality observed over the past few decades and the failure in eradicating the d
Publikováno v:
Current Drug Discovery Technologies. 17:154-165
Background:In the past decade CADD has emerged as a rational approach in drug development so with the help molecular docking approach we planned to perform virtual screening of the designed data set of Schiff bases of cinnamaldehyde. The research wor
Publikováno v:
International Journal of Quantitative Structure-Property Relationships. 5:44-62
Cosmetic manufacturers need to demonstrate the safety and efficacy of the products against microbial contamination to assure consumer safety and to improve shelf-life. The preservation strategies include chemical, physical, or physiological strategie