Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Neeraj Kumar, Saini"'
Publikováno v:
ADMET and DMPK, Vol 6, Iss 3, Pp 242-257 (2018)
A simple, sensitive and rapid assay method has been developed and validated for the estimation of enzalutamide, N-desmethylenzalutamide (active metabolite of enzalutamide), darolutamide and ORM-15341 (active metabolite of darolutamide) on mice dried
Externí odkaz:
https://doaj.org/article/1c851d4b63154280a6ace27823aec114
Autor:
Divyansh Srivastava, Utkarsh Chadha, Neha Gunreddy, Neeraj Kumar Saini, Nadheem Nassar Matara, Omkar Machindar, Udit Vendant Mishra, Mayank Khanna, S Ram Kishore, Senthil Kumaran Selvaraj
Publikováno v:
Materials Today: Proceedings. 64:870-882
Autor:
Mohd Zainuddin, Umesh Todmal, Narayanan Balaji, Ramesh Mullangi, Nuggehally R. Srinivas, Bhavesh Babulal Gabani, Vinay Kiran, Saibabu Polina, Neeraj Kumar Saini, Suresh P. Sulochana
Publikováno v:
Drug Metabolism Letters. 14:54-65
Background: Darolutamide is recently approved for the treatment of non-metastatic castrate resistance prostate cancer. Hitherto, no stereoselective pharmacokinetic data have been published pertaining to darolutamide and its diastereomers in animals o
Autor:
Ramesh Mullangi, Mohd Zainuddin, Praharaj Shuvranshu, Nuggehally R. Srinivas, Umesh Todmal, Bhavesh Babulal Gabani, Neeraj Kumar Saini, Suresh P. Sulochana, Narayanan Balaji, Vinod Anera Balakrishna, Ashok Timmapuram
Publikováno v:
Xenobiotica. 50:222-231
Levodropropizine (LDP) is a non-opioid anti-tussive. The stereoselective pharmacokinetics and tissue distribution (TD) of LDP vs. dextrodropropizine (DDP) have been characterized after oral...
Autor:
Ravi Kumar Trivedi, Nuggehally R. Srinivas, Ravi Kumar Jairam, Pavan Shrinivas, Neeraj Kumar Saini, Ramesh Mullangi, Bhavesh Babulal Gabani
Publikováno v:
Biomedical Chromatography. 34
A selective, sensitive and rapid LC-MS/MS method has been developed and validated as per US Food and Drug Administration regulatory guidelines for the simultaneous quantitation of colchicine and febuxostat in rat plasma. Colchicine and febuxostat wer
Autor:
Neeraj Kumar Saini, Suresh P. Sulochana, Mahanandeesha S. Hallur, Ramesh Mullangi, Sridharan Rajagopal, Swapan Kumar Samanta, Anup H.A. Siddesh, Bhavesh Babulal Gabani, Vinay Kiran
Publikováno v:
Drug research. 70(7)
SAFit-1 and SAFit-2 are selective FKBP51 (FK506-binding protein 51) ligands. In this paper, we present the development and validation data of an LC-MS/MS method for the simultaneous quantitation of SAFit-1 and SAFit-2 in mice plasma as per FDA regula
Autor:
Ramesh Mullangi, Neeraj Kumar Saini, Ravi Kanth Bhamidipati, P. Suresh, Mahalakhsmi Lella, Sriram Rajagopal
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 148:100-107
A sensitive, specific and rapid LC-ESI-MS/MS method has been developed and validated for the quantification of tideglusib in mice plasma using warfarin as an internal standard (I.S.) as per regulatory guidelines. Sample preparation was accomplished t
Autor:
Bhavesh Babulal, Gabani, Umesh, Todmal, Neeraj Kumar, Saini, Vinod A, Balakrishna, Suresh P, Sulochana, Ashok, Timmapuram, Mohd, Zainuddin, Narayanan, Balaji, Praharaj, Shuvranshu, Nuggehally R, Srinivas, Ramesh, Mullangi
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(2)
Levodropropizine (LDP) is a non-opioid anti-tussive. The stereoselective pharmacokinetics and tissue distribution (TD) of LDP vs. dextrodropropizine (DDP) have been characterized after oral and
Autor:
Ramesh Mullangi, Wolfgang Richter, Nuggehally R. Srinivas, Vinay Kiran, Sadanand Rangnathrao Mallurwar, Neeraj Kumar Saini, Suresh P. Sulochana
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 174
A selective, sensitive and rapid mice dried blood spot (DBS) method has been developed and validated for the simultaneous quantification of bendamustine (BM) and γ-hydroxy-bendamustine (HBM) as per regulatory guidelines using an LC-MS/MS. Quality co
Autor:
Rajesh Chandran, Ramesh Mullangi, Umesh Todmal, Neeraj Kumar Saini, Suresh P. Sulochana, Narayanan Balaji, Bhavesh Babulal Gabani
Publikováno v:
Biomedical chromatography : BMC. 33(3)
We developed and validated a simple, sensitive, selective and reliable LC-ESI-MS/MS method for direct quantitation of dropropizine enantiomers namely levodropropizine (LDP) and dextrodropropizine (DDP) in rat plasma without the need for derivatizatio