Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Neepa Y. Choksi"'
Autor:
Alexander Sedykh, Neepa Y. Choksi, David G. Allen, Warren M. Casey, Ruchir Shah, Nicole C. Kleinstreuer
Publikováno v:
Chemical Research in Toxicology. 35:992-1000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d8c86a24deed1998300e46781192b3
https://doi.org/10.1021/acs.chemrestox.1c00443
https://doi.org/10.1021/acs.chemrestox.1c00443
Autor:
Warren M, Casey, Xiaoqing, Chang, David G, Allen, Patricia C, Ceger, Neepa Y, Choksi, Jui-Hua, Hsieh, Barbara A, Wetmore, Stephen S, Ferguson, Michael J, DeVito, Catherine S, Sprankle, Nicole C, Kleinstreuer
Publikováno v:
Environmental Health Perspectives
Background: To effectively incorporate in vitro data into regulatory use, confidence must be established in the quantitative extrapolation of in vitro activity to relevant end points in animals or humans. Objective: Our goal was to evaluate and optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0addec334164cd75c0738a6a44225a7e
https://pubmed.ncbi.nlm.nih.gov/30192161
https://pubmed.ncbi.nlm.nih.gov/30192161
Publikováno v:
Brain Research. 852:151-160
A series of novel phenylaminotetralins (PATs) previously was shown to recognize discrete binding sites that are stereoselectively labeled by [ 3 H ]-(−)-trans-1-phenyl-3-N,N-dimethylamino-1,2,3,4-tetrahydronaphthalene (H2-PAT) and highly localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f854ba3fa5f986c2946a509945ff02
https://doi.org/10.1016/s0006-8993(99)02228-3
https://doi.org/10.1016/s0006-8993(99)02228-3
Publikováno v:
Toxicological Sciences. 39:76-80
Effects of Polychlorinated Biphenyls (PCBs) on Brain Tyrosine Hydroxylase Activity and Dopamine Synthesis in Rats. Choksi, N. Y., Kodavanti, P. R. S., Tilson, H. A., and Booth, R. G. (1997).Fundam. Appl. Toxicol.39, 76–80. Literature reports sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e790660613cff510bb7d9730312a078e
https://doi.org/10.1093/toxsci/39.1.76
https://doi.org/10.1093/toxsci/39.1.76
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 68(6)
The highly conserved nature of the thyroid gland and the thyroid system among mammalian species suggests it is critical to species survival. Studies show the thyroid system plays a critical role in the development of several organ systems, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3bd3b3b88b1d10d7978fe56a0ae040
https://pubmed.ncbi.nlm.nih.gov/14745982
https://pubmed.ncbi.nlm.nih.gov/14745982
Autor:
Neepa Y. Choksi, Remko A. Bakker, Henk Timmerman, Rob Leurs, Raymond G. Booth, William B. Nix, Nader H. Moniri
Publikováno v:
Booth, R G, Moniri, N H, Bakker, R A, Choksi, N Y, Nix, W B, Timmerman, H & Leurs, R 2002, ' A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors ', The Journal of Pharmacology and Experimental Therapeutics, vol. 302, no. 1, pp. 328-36 . https://doi.org/10.1124/jpet.302.1.328
The Journal of Pharmacology and Experimental Therapeutics, 302(1), 328-36. American Society for Pharmacology and Experimental Therapeutics
The Journal of Pharmacology and Experimental Therapeutics, 302(1), 328-36. American Society for Pharmacology and Experimental Therapeutics
Previously, (−)- trans -1-phenyl-3- N , N -dimethylamino-1,2,3,4-tetrahydronaphthalene ([−]- trans -H 2 -PAT) was shown to activate stereospecifically histamine H 1 receptors coupled to modulation of tyrosine hydroxylase activity in guinea pig an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16a23a4d50ec9c74f2e0e3d7b8a42f1
https://research.vu.nl/en/publications/e04cd273-9daf-4df4-b731-96b72716adb4
https://research.vu.nl/en/publications/e04cd273-9daf-4df4-b731-96b72716adb4
Publikováno v:
Brain research. 761(1)
The adenosine agonist 2-phenylaminoadenosine (PAD) stimulated tyrosine hydroxylase activity in rat striatum in vitro. This effect was selectively blocked by the A2 antagonist 8-chlorostyrylcaffeine (CSC), suggesting an A2 receptor-mediated mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2842726940271d3f3f30c5f1f30a314e
https://pubmed.ncbi.nlm.nih.gov/9247078
https://pubmed.ncbi.nlm.nih.gov/9247078