Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Neena S Agrawal"'
Autor:
Neena S Agrawal, Xiaomu Wei, John R. Wunderlich, Yardena Samuels, Julia C. Cronin, Todd D. Prickett, Jimmy Lin, Pedro Cruz, Steven A. Rosenberg, Kristin E. Yates
Publikováno v:
Nature Genetics. 41:1127-1132
Tyrosine phosphorylation is important in signaling pathways underlying tumorigenesis. We performed a mutational analysis of the protein tyrosine kinase (PTK) gene family in cutaneous metastatic melanoma. We identified 30 somatic mutations affecting t
Autor:
Boris C. Bastian, John R. Wunderlich, Steven A. Rosenberg, Julia C. Cronin, Swapna S. Vemula, Neena S Agrawal, Stacie K. Loftus, William J. Pavan, Phillip Buckhaults, Yardena Samuels, Katie Ridd, Carolyn E. Banister, Allison S. Burrell, Todd D. Prickett, Xiaomu Wei, Jimmy Lin
Publikováno v:
Pigment cellmelanoma research. 22(4)
Microphthalmia-associated transcription factor (MITF) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary and metastatic l
Autor:
Michael P. O'Connell, Patricia Fetsch, Shelley Hoogstraten-Miller, Xiaomu Wei, Jason D. Howard, Wendy Westbroek, Jimmy Lin, Julia C. Cronin, John R. Wunderlich, Sean Davis, Allison S. Burrell, Chenwei Wang, Alfredo A. Molinolo, Yardena Samuels, Carolyn E. Banister, Armando C. Filie, Todd D. Prickett, Lavanya H. Palavalli, Neena S Agrawal, Ashani T. Weeraratna, Steven A. Rosenberg, Patricia Porter-Gill, Lawrence C. Brody, Phillip Buckhaults
Publikováno v:
Nature genetics. 41(5)
A mutational analysis of the matrix metalloproteinase (MMP) gene family in human melanoma identified somatic mutations in 23% of melanomas. Five mutations in one of the most commonly mutated genes, MMP8, reduced MMP enzyme activity. Expression of wil
Autor:
Steven A. Rosenberg, Julia C. Cronin, Yardena Samuels, Neena S Agrawal, Pedro Cruz, J. Lin, Todd D. Prickett, Xiaomu Wei, Kristin E. Yates, John R. Wunderlich
Publikováno v:
Cancer Research. 70:2221-2221
One of the most important features of cellular signaling involves the addition (or removal) of phosphate groups. Protein phosphorylation is coordinately regulated by protein kinases and phosphatases. Protein kinases are the largest superfamily of con