Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Neena Rane"'
Publikováno v:
Oncogene. 22:1124-1134
Recent genetic investigations have established that RhoB gain-of-function is sufficient to mediate the antitransforming effects of farnesyltransferase inhibitors (FTIs) in H-Ras-transformed fibroblast systems. In this study, we addressed the breadth
Publikováno v:
Molecular and Cellular Biology. 21:6906-6912
RhoB is an endosomal small GTPase that is implicated in the response to growth factors, genotoxic stress, and farnesyltransferase inhibitors. To gain insight into its physiological functions we examined the consequences of homozygous gene deletion in