Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Neeliyath A. Ramakrishnan"'
Autor:
Neeliyath A. Ramakrishnan, Dakshnamurthy Selvakumar, Nathan A. Deckard, Dennis G. Drescher, Barbara J. Morley, Marian J. Drescher
Publikováno v:
Biochemical Journal. 474:79-104
Dopamine receptors regulate exocytosis via protein–protein interactions (PPIs) as well as via adenylyl cyclase transduction pathways. Evidence has been obtained for PPIs in inner ear hair cells coupling D1A to soluble N-ethylmaleimide-sensitive fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010e0a72a12195745d63ce1a8083d8b2
https://doi.org/10.1042/bcj20160690
https://doi.org/10.1042/bcj20160690
Autor:
Barbara J. Morley, Marian J. Drescher, Philip M. Kelley, Neeliyath A. Ramakrishnan, Dennis G. Drescher
Publikováno v:
Journal of Biological Chemistry. 289:8750-8766
Mutations in otoferlin, a C2 domain-containing ferlin family protein, cause non-syndromic hearing loss in humans (DFNB9 deafness). Furthermore, transmitter secretion of cochlear inner hair cells is compromised in mice lacking otoferlin. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5859d699eaca7ebb1f33054a18f5b982
https://doi.org/10.1074/jbc.m113.480533
https://doi.org/10.1074/jbc.m113.480533
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1427
Surface plasmon resonance is an optical technique that is utilized for detecting molecular interactions. Binding of a mobile molecule (analyte) to a molecule immobilized on a thin metal film (ligand) changes the refractive index of the film. The angl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b2d3a5ef1576c8798c32b56f4c041aa
https://pubmed.ncbi.nlm.nih.gov/27259927
https://pubmed.ncbi.nlm.nih.gov/27259927
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936137
Surface plasmon resonance is an optical technique that is utilized for detecting molecular interactions. Binding of a mobile molecule (analyte) to a molecule immobilized on a thin metal film (ligand) changes the refractive index of the film. The angl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a9fb20d1c1ce982483a7782c427331b
https://doi.org/10.1007/978-1-4939-3615-1_10
https://doi.org/10.1007/978-1-4939-3615-1_10
Autor:
James S. Hatfield, Neeliyath A. Ramakrishnan, Marian J. Drescher, Dennis G. Drescher, Khalid Mohammed Khan
Publikováno v:
Journal of Biological Chemistry. 287:37628-37646
A unique coupling between HCN1 and stereociliary tip-link protein protocadherin 15 has been described for a teleost vestibular hair-cell model and mammalian organ of Corti (OC) (Ramakrishnan, N. A., Drescher, M. J., Barretto, R. L., Beisel, K. W., Ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f00d00cffb52d545f080857ca1af286c
https://doi.org/10.1074/jbc.m112.375832
https://doi.org/10.1074/jbc.m112.375832
Publikováno v:
Molecular and Cellular Neuroscience. 50:58-69
Transmitter release at synapses ensures faithful chemical coding of information that is transmitted in the sub-second time frame. The brain, the central unit of information processing, depends upon fast communication for decision making. Neuronal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d016a00071a0e7b0e9021fb853a27a
https://doi.org/10.1016/j.mcn.2012.03.009
https://doi.org/10.1016/j.mcn.2012.03.009
Autor:
James S. Hatfield, Marian J. Drescher, Neeliyath A. Ramakrishnan, Jayme R. Dowdall, Dennis G. Drescher, Khalid M. Khan, Dakshnamurthy Selvakumar
Publikováno v:
Biochemical Journal. 443:463-476
The molecular characteristics of CNG (cyclic nucleotide-gated) channels in auditory/vestibular hair cells are largely unknown, unlike those of CNG mediating sensory transduction in vision and olfaction. In the present study we report the full-length
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771098da7ae89b3c808dbb49fe4ffb64
https://doi.org/10.1042/bj20111255
https://doi.org/10.1042/bj20111255
Autor:
Roberto L. Barretto, Dennis G. Drescher, Marian J. Drescher, James S. Hatfield, Neeliyath A. Ramakrishnan, Kirk W. Beisel
Publikováno v:
Journal of Biological Chemistry. 284:3227-3238
The cytoplasmic amino terminus of HCN1, the primary full-length HCN isoform expressed in trout saccular hair cells, was found by yeast two-hybrid protocols to bind the cytoplasmic carboxyl-terminal domain of a protocadherin 15a-like protein. HCN1 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d52a13b6f046f8b27c6f82f8eaae17
https://doi.org/10.1074/jbc.m806177200
https://doi.org/10.1074/jbc.m806177200
Autor:
Marian J. Drescher, James S. Hatfield, Neeliyath A. Ramakrishnan, Dennis G. Drescher, Khalid M. Khan
Publikováno v:
Journal of Neuroscience Research. 85:3000-3012
Alpha(1)-, beta(1)-, and beta(2)-adrenergic receptors (ARs), which mediate responses to adrenergic input, have been immunohistochemically identified within the organ of Corti and spiral ganglion with polyclonal antibodies of established specificity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b78329ebbb42c6cd64b24718a1e1227
https://doi.org/10.1002/jnr.21404
https://doi.org/10.1002/jnr.21404
Autor:
Neeliyath A. Ramakrishnan, James S. Hatfield, Khalid M. Khan, Dennis G. Drescher, Marian J. Drescher, M.D. Abu-Hamdan, L.A. Lemonnier
Publikováno v:
Neuroscience. 142:139-164
Pituitary adenylyl cyclase-activating polypeptide (PACAP), via its specific receptor pituitary adenylyl cyclase-activating polypeptide receptor 1 (PAC1-R), is known to have roles in neuromodulation and neuroprotection associated with glutamatergic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1268da12ff510646e2013c94bbcb3a6
https://doi.org/10.1016/j.neuroscience.2006.05.065
https://doi.org/10.1016/j.neuroscience.2006.05.065