Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Neelesh Maheshwari"'
Publikováno v:
Pharmacognosy Research. 15:42-55
Publikováno v:
Pharmacognosy Research. 15:64-70
Autor:
Piyush Trivedi, Chandan Sahi, Chandrabose Karthikeyan, Neelesh Maheshwari, Amit Kumar Verma, N. S. Hari Narayana Moorthy, Shraddha V. Bhadada
Publikováno v:
Letters in Drug Design & Discovery. 18:121-130
Background : The discovery of novel antidiabetics for the treatment of type 2 diabetes mellitus (T2DM) is an important task nowadays because the current treatment approaches have certain limitations. The reported studies showed that the protein tyros
Publikováno v:
Journal of The Institution of Engineers (India): Series C. 102:349-359
Brake discs are crucial part of any automobile, since they provide frictional effect for braking. They should be reliable and have long functional life. In this regard, both the fatigue life of the brake disc and its ability to resist axial deflectio
Autor:
Shruti Jain, Neelesh Maheshwari, Anjali Padria, Jaydeep Singh Baghel, RK Maheshwari, Pawan Mulani
Publikováno v:
Journal of Drug Delivery and Therapeutics. 9:244-249
As per the mixed solvency concept (proposed by Dr. R.K. Maheshwari), each and every substance present on the earth has got solubilizing property i.e. all the liquids, gases and solids possess solubilizing power. In the mixed solvency concept, each su
Autor:
Amit Kumar Verma, N. S. Hari Narayana Moorthy, Neelesh Maheshwari, Piyush Trivedi, Chandan Sahi, C. Karthikeyan, Shraddha V. Bhadada
Publikováno v:
Bioorganic chemistry. 92
A series of ten N-(3-(1H-tetrazole-5-yl)phenyl)acetamide derivatives (NM-07 to NM-16) designed from a lead molecule identified previously in our laboratory were synthesized and evaluated for protein tyrosine phosphatase 1B (PTP1B) inhibitory activity
Autor:
Anirban Roy Chowdhury, Jigar Soni, Amit Mukharya, Mona Kapil, Tushar Mehta, Neelesh Maheshwari
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 189:113292
Inorganic impurity analysis of pharmaceutical drug products is of paramount importance at trace levels due to the availability of toxic metals. The existing techniques require extensive development and chemical treatment to evaluate the presence of c
Autor:
Shraddha V. Bhadada, Amit Kumar Verma, Neelesh Maheshwari, Piyush Trivedi, Chandan Sahi, N. S. Hari Narayana Moorthy, Chandrabose Karthikeyan
Publikováno v:
Bioorganic chemistry. 80
Described herein is the synthesis and biological evaluation of a series of non-carboxylic inhibitors of Protein Tyrosine Phosphatase 1B designed using bioisosteric replacement strategy. Six N-(3-(1H-tetrazol-5-yl)phenyl)acetamide derivatives designed
Publikováno v:
Current drug targets. 19(5)
Background Protein tyrosine phosphatase 1B (PTP1B) is an important therapeutic target for type II diabetes and obesity because of its pivotal role as a negative modulator in both insulin and leptin signalling pathways. Objective The discovery of PTP1