Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Neelesh C Reddy"'
Autor:
Neelesh C. Reddy, Rajib Molla, Pralhad Namdev Joshi, Sajeev T. K., Ipsita Basu, Jyotsna Kawadkar, Neetu Kalra, Ram Kumar Mishra, Suman Chakrabarty, Sanjeev Shukla, Vishal Rai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Controlling the selectivity of the chemical modification of a genetic-manipulation-free protein is currently problematic. Here the authors report a method using cysteine-based chemoselective Linchpin Directed site-selective Modification of the lysine
Externí odkaz:
https://doaj.org/article/06df9bfd5b40499cacef9975977e5b0c
Publikováno v:
Chemical Communications. 57:7083-7095
Proteins provide an excellent means to monitor and regulate biological processes. Hence, a precise chemical toolbox for their modification becomes indispensable. In this perspective, this feature article outlines our efforts to establish the core pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619d6d9cc0bac8464388cff386753ff5
https://doi.org/10.1039/d1cc02268g
https://doi.org/10.1039/d1cc02268g
Publikováno v:
Organic & Biomolecular Chemistry. 18:4669-4691
The library of chemical reactions for C-C and C-heteroatom bond formation is exceptional. The understanding of reactivity and diverse aspects of selectivity facilitates the functional group transformation of high complexity. However, the same is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d26bb6546f27693c5a0b798bba7a21
https://doi.org/10.1039/d0ob00857e
https://doi.org/10.1039/d0ob00857e
Autor:
Vishal Rai, Surya Dev Mishra, T K Sajeev, Neelesh C Reddy, Landa Purushottam, V B Unnikrishnan, Mansi Gujrati, Ram Kumar Mishra, Dattatraya Gautam Rawale, Srinivasa Rao Adusumalli
Publikováno v:
Chemical Science
Analytically pure proteins are indispensable for diverse applications, including therapeutics. Here, we report a methodology where a single amino acid, glycine, enables metal-free protein purification. This robust platform is enabled by a Gly-tag res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4042ae20a3ee20ff4e107af36e8eea9c
https://doi.org/10.1039/d0sc01153c
https://doi.org/10.1039/d0sc01153c
Autor:
Neelesh C Reddy, Srinivasa Rao Adusumalli, Kalyani Thakur, Sanjeev Shukla, Dattatraya Gautam Rawale, Neetu Kalra, Landa Purushottam, Vishal Rai
Publikováno v:
Angewandte Chemie (International ed. in English). 59(26)
The necessity for precision labeling of proteins emerged during the efforts to understand and regulate their structure and function. It demands selective attachment of tags such as affinity probes, fluorophores, and potent cytotoxins. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929cdd5d6da9497bb1959e3a5c4e0ee1
https://pubmed.ncbi.nlm.nih.gov/32171045
https://pubmed.ncbi.nlm.nih.gov/32171045
Publikováno v:
Chemical communications (Cambridge, England). 55(67)
A chemical tag enhances peptide detection by multiple orders in mass spectrometry. The substantial improvement in the peptide mapping along with simplified and enhanced fragmentation pattern enables the unambiguous sequencing of a protein and antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2159c24f2cf8dbd9beaceb75d02a90
https://pubmed.ncbi.nlm.nih.gov/31367719
https://pubmed.ncbi.nlm.nih.gov/31367719