Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Neelankal John, A."'
Publikováno v:
In Revista Espanola de Geriatria y Gerontologia March-April 2020 55(2):70-75
Publikováno v:
FEBS Open Bio, Vol 10, Iss 1, Pp 28-40 (2020)
The functional state (FS) of adult pancreatic islets is regulated by a large array of regulatory molecules including numerous transcription factors. Whether any islet structural molecules play such a role has not been well understood. Here, multiple
Externí odkaz:
https://doaj.org/article/37eb1df581bd45cfb92a11e63c42ebca
Publikováno v:
In Diabetes & Metabolism June 2018 44(3):269-280
Publikováno v:
Revista Española de Geriatría y Gerontología. 55:70-75
Introduction Health professionals are progressively drawing on the concept of frailty as a determinant of adverse surgical outcomes in of older adults. We aimed to determine the prevalence of frailty and the correlation between frailty and mortality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6a690dc59e3fd1272da08bfff4db5e
https://doi.org/10.1016/j.regg.2019.09.005
https://doi.org/10.1016/j.regg.2019.09.005
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 1, Pp 28-40 (2020)
FEBS Open Bio, Vol 10, Iss 1, Pp 28-40 (2020)
The functional state (FS) of adult pancreatic islets is regulated by a large array of regulatory molecules including numerous transcription factors. Whether any islet structural molecules play such a role has not been well understood. Here, multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee0abef193090014c89ebbb60d91277
https://doi.org/10.1002/2211-5463.12735
https://doi.org/10.1002/2211-5463.12735
RNA-Seq Analysis of Islets to Characterise the Dedifferentiation in Type 2 Diabetes Model Mice db/db
Publikováno v:
Endocrine Pathology. 29:207-221
Type 2 diabetes (T2D) is a global health issue and dedifferentiation plays underlying causes in the pathophysiology of T2D; however, there is a lack of understanding in the mechanism. Dedifferentiation results from the loss of function of pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614a0a52e6d273abdb75231b9a3ba147
https://doi.org/10.1007/s12022-018-9523-x
https://doi.org/10.1007/s12022-018-9523-x
Publikováno v:
Journal of Neuroendocrinology. Jan2017, Vol. 29 Issue 1, p1-N.PAG. 12p. 1 Chart, 4 Graphs.
Autor:
Revathy Carnagarin, Rodrigo Carlessi, Nikita L. Walz, Fang-Xu Jiang, Philip Newsholme, Younan Chen, Kevin N. Keane, Vinicius Fernandes Cruzat, Abraham Neelankal John, Crispin R. Dass
Publikováno v:
Molecular and Cellular Endocrinology. 426:50-60
Pigment epithelium-derived factor (PEDF) is a multifunctional glycoprotein, associated with lipid catabolism and insulin resistance. In the present study, PEDF increased chronic and acute insulin secretion in a clonal rat β-cell line BRIN-BD11, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5238ad1f74e0577141be566b28a0b5
https://doi.org/10.1016/j.mce.2016.02.004
https://doi.org/10.1016/j.mce.2016.02.004
Publikováno v:
Diabetesmetabolism. 44(3)
Dedifferentiation has been identified as one of the causes of β-cell failure resulting in type 2 diabetes (T2D). This study tested whether increasing vitamin D receptor (VDR) expression prevents dedifferentiation of β cells in a high-glucose state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5936e968431574b6cf92a1623c361797
https://pubmed.ncbi.nlm.nih.gov/28918929
https://pubmed.ncbi.nlm.nih.gov/28918929
Publikováno v:
Journal of Neuroendocrinology. 29
There is increasing evidence to suggest that type 2 diabetes mellitus (T2D), a pandemic metabolic disease, may be caused by β-cell dedifferentiation (βCD). However, there is currently no universal definition of βCD, and the underlying mechanism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4b320f022248bf87a8c5b09454b2f5
https://doi.org/10.1111/jne.12450
https://doi.org/10.1111/jne.12450