Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Neelanjan Bose"'
Autor:
Muniesh Muthaiyan Shanmugam, Jyotiska Chaudhuri, Durai Sellegounder, Amit Kumar Sahu, Sanjib Guha, Manish Chamoli, Brian Hodge, Neelanjan Bose, Charis Amber, Dominique O Farrera, Gordon Lithgow, Richmond Sarpong, James J Galligan, Pankaj Kapahi
Publikováno v:
eLife, Vol 12 (2023)
The Maillard reaction, a chemical reaction between amino acids and sugars, is exploited to produce flavorful food ubiquitously, from the baking industry to our everyday lives. However, the Maillard reaction also occurs in all cells, from prokaryotes
Externí odkaz:
https://doaj.org/article/3097fcc5f4754bfc8ebd212152332174
Autor:
Jacob Rose, Nathan Basisty, Tiffany Zee, Cameron Wehrfritz, Neelanjan Bose, Pierre-Yves Desprez, Pankaj Kapahi, Marshall Stoller, Birgit Schilling
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0250137 (2022)
Cystinuria is one of various disorders that cause biomineralization in the urinary system, including bladder stone formation in humans. It is most prevalent in children and adolescents and more aggressive in males. There is no cure, and only limited
Externí odkaz:
https://doaj.org/article/09cabd0021514b83860dac1d85d0c647
Autor:
Zheng Liu, Maro J. Kariya, Christopher D. Chute, Amy K. Pribadi, Sarah G. Leinwand, Ada Tong, Kevin P. Curran, Neelanjan Bose, Frank C. Schroeder, Jagan Srinivasan, Sreekanth H. Chalasani
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Defensive behavioral responses can be triggered by predator-released odors. Here, the authors identified the relevant Pristionchus pacificus-released sulfolipid molecules and dissected the neural circuits underlying C. elegans response to this predat
Externí odkaz:
https://doaj.org/article/15b6645a0d3c438aa0f7c65f94dc1b17
Autor:
Sven Lang, Tyler A Hilsabeck, Kenneth A Wilson, Amit Sharma, Neelanjan Bose, Deanna J Brackman, Jennifer N Beck, Ling Chen, Mark A Watson, David W Killilea, Sunita Ho, Arnold Kahn, Kathleen Giacomini, Marshall L Stoller, Thomas Chi, Pankaj Kapahi
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008318 (2019)
Elevated uric acid (UA) is a key risk factor for many disorders, including metabolic syndrome, gout and kidney stones. Despite frequent occurrence of these disorders, the genetic pathways influencing UA metabolism and the association with disease rem
Externí odkaz:
https://doaj.org/article/8215a5e6533541639565d4c0aab3138d
Publikováno v:
Bio-Protocol, Vol 7, Iss 14 (2017)
Cystinuria is a rare genetic disorder characterized by recurrent, painful kidney stones, primarily composed of cystine, the dimer of the amino acid cysteine (Sumorok and Goldfarb, 2013). Using a mouse model of cystinuria, we have recently shown that
Externí odkaz:
https://doaj.org/article/f8f967e9b5ae4f159bf8f521378f625c
Autor:
Thomas Chi, Man Su Kim, Sven Lang, Neelanjan Bose, Arnold Kahn, Lawrence Flechner, Sarah D Blaschko, Tiffany Zee, Gulinuer Muteliefu, Nichole Bond, Marysia Kolipinski, Sirine C Fakra, Neil Mandel, Joe Miller, Arvind Ramanathan, David W Killilea, Katja Brückner, Pankaj Kapahi, Marshall L Stoller
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124150 (2015)
Ectopic calcification is a driving force for a variety of diseases, including kidney stones and atherosclerosis, but initiating factors remain largely unknown. Given its importance in seemingly divergent disease processes, identifying fundamental pri
Externí odkaz:
https://doaj.org/article/c037513fa2214d06aa353b1e53a952e3
Autor:
Jagan Srinivasan, Stephan H von Reuss, Neelanjan Bose, Alon Zaslaver, Parag Mahanti, Margaret C Ho, Oran G O'Doherty, Arthur S Edison, Paul W Sternberg, Frank C Schroeder
Publikováno v:
PLoS Biology, Vol 10, Iss 1, p e1001237 (2012)
The nematode C. elegans is an important model for the study of social behaviors. Recent investigations have shown that a family of small molecule signals, the ascarosides, controls population density sensing and mating behavior. However, despite exte
Externí odkaz:
https://doaj.org/article/7345f089cb33440abfaa83f036afae50
Autor:
Tyler A. U. Hilsabeck, Ru Liu-Bryan, Tracy Guo, Kenneth A. Wilson, Neelanjan Bose, Daniel Raftery, Jennifer N. Beck, Sven Lang, Kelly Jin, Christopher S. Nelson, Tal Oron, Marshall Stoller, Daniel Promislow, Rachel B. Brem, Robert Terkeltaub, Pankaj Kapahi
Publikováno v:
GeroScience, vol 44, iss 4
GeroScience
GeroScience
Elevated serum urate (hyperuricemia) promotes crystalline monosodium urate tissue deposits and gout, with associated inflammation and increased mortality. To identify modifiers of uric acid pathologies, we performed a fly Genome-Wide Association Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4657fbfcc42b6acd5163051fb15ec7
https://escholarship.org/uc/item/20c3d830
https://escholarship.org/uc/item/20c3d830
Autor:
Pankaj Kapahi, Karina Ky, M. Arthur Moseley, Lisa St. John-Williams, Vagisha Sharma, Laura G. Dubois, Kevin M. Perrott, Carol A. Colton, Brendan MacLean, J. Will Thompson, Kendra J. Adams, Neelanjan Bose, Brian S. Pratt, Michael J. MacCoss, Birgit Schilling
Publikováno v:
Journal of Proteome Research. 19:1447-1458
Vendor-independent software tools for quantification of small molecules and metabolites are lacking, especially for targeted analysis workflows. Skyline is a freely available, open-source software tool for targeted quantitative mass spectrometry meth
Autor:
Kenta Shinoda, Andrea Choe, Kiyoshi Hirahara, Masahiro Kiuchi, Kota Kokubo, Tomomi Ichikawa, Jason S. Hoki, Akane S. Suzuki, Neelanjan Bose, Judith A. Appleton, Raffi V. Aroian, Frank C. Schroeder, Paul W. Sternberg, Toshinori Nakayama
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(9)
Mounting evidence suggests that nematode infection can protect against disorders of immune dysregulation. Administration of live parasites or their excretory/secretory (ES) products has shown therapeutic effects across a wide range of animal models f