Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Neelakantan Saikrishnan"'
Publikováno v:
Cardiovascular Engineering and Technology. 9:273-287
Experimental flow field characterization is a critical component of the assessment of the hemolytic and thrombogenic potential of heart valve substitutes, thus it is important to identify best practices for these experimental techniques. This paper p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09850b83aa9151310ab49a24a167e58
https://doi.org/10.1007/s13239-018-0348-z
https://doi.org/10.1007/s13239-018-0348-z
Autor:
Michael Markl, Lucia Mirabella, Neelakantan Saikrishnan, Ajit P. Yoganathan, Elizabeth R. Coco, Daniel Mangiameli, Alex J. Barker
Publikováno v:
Annals of Biomedical Engineering. 43:1815-1827
Bicuspid aortic valve (BAV) is the most common congenital heart defect and can lead to severe complications. Many studies have been conducted to evaluate the potential of geometric and hemodynamic biomarkers to predict BAV-related aortopathy. This wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cf8a59bc3781a9016f0666db389e70
https://doi.org/10.1007/s10439-014-1214-2
https://doi.org/10.1007/s10439-014-1214-2
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 14:577-588
Congenital bicuspid aortic valves (BAVs) are associated with accelerated disease progression, such as leaflet calcification and ascending aorta dilatation. Although common underlying genetic factors have been implicated in accelerated disease in BAV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea14dbd198caef5e2650c61124af874
https://doi.org/10.1007/s10237-014-0623-3
https://doi.org/10.1007/s10237-014-0623-3
Publikováno v:
Circulation. 129:244-253
Aortic valve (AV) stenosis is one of the most common valvular diseases and is the third most common cardiovascular disease in developed countries. It occurs in ≈2.8% of patients ≥75 years of age and can occur because of degenerative calcification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620df1aab9b834b0fdc7ffd333109d35
https://doi.org/10.1161/circulationaha.113.002310
https://doi.org/10.1161/circulationaha.113.002310
Publikováno v:
Annals of Biomedical Engineering. 42:526-540
A number of clinical, in vitro and computational studies have shown the potential for thromboembolic complications in bileaflet mechanical heart valves (BMHV), primarily due to the complex and unsteady flows in the valve hinges. These studies have fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d03c4b18c2f32c2be8086034a90d9c
https://doi.org/10.1007/s10439-013-0919-y
https://doi.org/10.1007/s10439-013-0919-y
Autor:
Neelakantan Saikrishnan, Karyn S. Kunzelman, Jean-Pierre Rabbah, Ajit Prithivaraj Yoganathan, Andrew W. Siefert
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering. 18:618-627
Computational models for the heart’s mitral valve (MV) exhibit several uncertainties which may be reduced by further developing these models using ground-truth data sets. The present study generated a ground-truth data set by quantifying the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8f02f042597a548044dd1ef5db38d6
https://doi.org/10.1080/10255842.2013.822490
https://doi.org/10.1080/10255842.2013.822490
Autor:
Jean-Pierre Rabbah, Steven A. Touchton, Jorge Hernan Jimenez, Neelakantan Saikrishnan, Ajit P. Yoganathan, Andrew W. Siefert, Jeremy R. McGarvey, Robert C. Gorman, Satoshi Takebayashi, Joseph H. Gorman
Publikováno v:
Journal of Biomechanics. 46:2550-2553
Mitral annuloplasty has been a keystone to the success of mitral valve repair in functional mitral regurgitation. Understanding the complex interplay between annular-ring stresses and left ventricular function has significant implications for patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33baa1cbe710309332b420d86cb6122d
https://doi.org/10.1016/j.jbiomech.2013.07.013
https://doi.org/10.1016/j.jbiomech.2013.07.013
Publikováno v:
Cardiovascular Engineering and Technology. 4:427-439
Transcatheter Aortic Valve Replacement (TAVR) is currently used for patients with aortic valve disease at high risk for surgical intervention. The Lotus™ Valve system (Boston Scientific) is a novel repositionable TAVR with bovine pericardial leafle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a886c87cb68f0cb2732f937eae4f4ab
https://doi.org/10.1007/s13239-013-0163-5
https://doi.org/10.1007/s13239-013-0163-5
Autor:
David A. Icenogle, Andrew W. Siefert, Jean-Pierre Rabbah, Stamatios Lerakis, Jarek Rossignac, Neelakantan Saikrishnan, Ajit P. Yoganathan
Publikováno v:
Annals of Biomedical Engineering. 41:1258-1268
Patient-specific models of the heart's mitral valve (MV) exhibit potential for surgical planning. While advances in 3D echocardiography (3DE) have provided adequate resolution to extract MV leaflet geometry, no study has quantitatively assessed the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e55551abbd28e8b4b5def675c309172
https://doi.org/10.1007/s10439-013-0784-8
https://doi.org/10.1007/s10439-013-0784-8
Autor:
Jean-Pierre Rabbah, Neelakantan Saikrishnan, Ajit P. Yoganathan, Andrew W. Siefert, Erin M. Spinner
Publikováno v:
The Annals of Thoracic Surgery. 94:1446-1453
Background Percutaneous edge-to-edge mitral valve (MV) repair is a potential therapeutic option for patients presenting with mitral regurgitation, who may not be suitable for surgery. We characterized the edge-to-edge repair forces in a posterior lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79818d0bbea1d8094fe9c02378aeaa12
https://doi.org/10.1016/j.athoracsur.2012.05.024
https://doi.org/10.1016/j.athoracsur.2012.05.024