Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Neelakandan Muthukumaran"'
Autor:
Abhilash K. Ravindranath, Lorna Rodriguez-Rodriguez, Neelakandan Muthukumaran, Karl E. Miletti-González
Publikováno v:
Molecular Cancer Research. 4:511-520
Chronic inflammation is implicated in the pathophysiology of ovarian cancer. Tumor necrosis factor-α (TNF-α), a major inflammatory cytokine, is abundant in the ovarian cancer microenvironment. TNF-α modulates the expression of CD44 in normal T lym
Autor:
William N. Hait, Karl E. Miletti-González, Shiling Chen, Lorna Rodriguez-Rodriguez, Jin Ming Yang, Weichung Joe Shih, Kevin Apolito, Neelakandan Muthukumaran, Giuseppa N. Saglimbeni, Xiaohua Wu
Publikováno v:
Cancer research. 65(15)
Invasion and metastases of cancer cells and the development of resistance to anticancer therapies are the main causes of morbidity and mortality from cancer. For more than two decades, these two important but not clearly related aspects in the biolog
Autor:
Darlene Gibbon, Murugesan Gounder, Mihae Song, Wilberto Nieves-Neira, Mira Hellmann, Lorna Rodriguez-Rodriguez, Susan Goodin, Ami Vaidya, Brian Buckley, Neelakandan Muthukumaran
Publikováno v:
Cancer Research. 74:CT219-CT219
Objective: The development of drug resistance is a major cause of gynecologic cancer deaths. Selenium (Se) inhibits the development of carboplatin (C) drug resistance in a mouse ovarian cancer xenograft model. Based on this data, a Phase I trial of a
Autor:
Christine L. Hostetter, Karl E. Miletti-González, Neelakandan Muthukumaran, Judith C. Keen, Abhilash K. Ravindranath, Lorna Rodriguez-Rodriguez
Publikováno v:
Cancer Research. 71:3078-3078
CD44, a major hyaluronic acid (HA) receptor, is involved in cell migration, metastasis and tumor progression. While in normal ovarian epithelium CD44 is not expressed, ovarian carcinoma cells express multiple CD44 isoforms as the tumor progresses and