Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Neelagandan Kamariah"'
Autor:
Vikrant Kumar, Puneeth Kumar Chunchagatta Lakshman, Thazhe Kootteri Prasad, Kavyashree Manjunath, Sneha Bairy, Akshaya S. Vasu, B. Ganavi, Subbarao Jasti, Neelagandan Kamariah
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23864- (2024)
Target-based discovery of first-in-class therapeutics demands an in-depth understanding of the molecular mechanisms underlying human diseases. Precise measurements of cellular and biochemical activities are critical to gain mechanistic knowledge of b
Externí odkaz:
https://doaj.org/article/db664869fa4c445ba01299e12ca67ed2
Autor:
Kavya R, Snehal Aouti, Sneha Jos, Thazhe Kootteri Prasad, Kumuda K N, Sruthi Unni, Balasundaram Padmanabhan, Neelagandan Kamariah, Sivaraman Padavattan, Rajeswara Babu Mythri
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fda3d9081130092fa2114256f4b01b0
https://doi.org/10.1080/07391102.2023.2175379
https://doi.org/10.1080/07391102.2023.2175379
Autor:
Subashini, Mathivanan, Puneeth Kumar, Chunchagatta Lakshman, Manvi, Singh, Saranya, Giridharan, Keerthana, Sathish, Manjunath A, Hurakadli, Kavitha, Bharatham, Neelagandan, Kamariah
Publikováno v:
ACS omega. 7(28)
The transcriptional activity of Forkhead Box O3 (FOXO3a) is inactivated by AKT-mediated phosphorylation on Serine 253 (S253), which enables FOXO3a binding to 14-3-3. Phosphorylated FOXO3a binding to 14-3-3 facilitates the nuclear exclusion of FOXO3a,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38d7d0f2059cd78bd1edc154009c7092
https://pubmed.ncbi.nlm.nih.gov/35874228
https://pubmed.ncbi.nlm.nih.gov/35874228
Publikováno v:
FEBS Letters. 594:2829-2839
The ability of Mycobacteria to overcome oxidative stress is of paramount importance for its survival within the host. One of the key enzymes that are involved in protecting the bacterium from reactive oxygen species is the catalase-peroxidase (KatG).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075761e8573af8a97bf0f245d5c223cd
https://doi.org/10.1002/1873-3468.13864
https://doi.org/10.1002/1873-3468.13864
Publikováno v:
Biochemical and Biophysical Research Communications. 527:518-524
The Na+-translocating F1FO ATP synthase from Acetobacterium woodii (AwF-ATP synthase) with a subunit stoichiometry of α3:β3:γ:δ:ε:a:b2:(c2/3)9:c1 represents an evolutionary path between ATP-synthases and vacuolar ATPases, by containing a heterom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d2b4eef58cc94da090aefc5072b513
https://doi.org/10.1016/j.bbrc.2020.04.026
https://doi.org/10.1016/j.bbrc.2020.04.026
Autor:
Deepak K. Jagannath, Ashwathi Valiyaparambil, Vysakh K. Viswanath, Manjunath A. Hurakadli, Neelagandan Kamariah, Alifia C. Jafer, Chhaya Patole, Sabyasachi Pradhan, Naveen Kumar, Anirudha Lakshminarasimhan
Publikováno v:
Analytical Biochemistry. 655:114830
Pfs25, a vaccine candidate, expressed on the surface of the malarial parasite, plays an important role in the development of Plasmodium falciparum. 1269, a monoclonal antibody targeting the epidermal growth factor-like domain 1 and epidermal growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad25679f141ba6021257f7f95491cd5
https://doi.org/10.1016/j.ab.2022.114830
https://doi.org/10.1016/j.ab.2022.114830
Autor:
Joon Shin, Ardina Grüber, Yew Kwang Toh, Asha Manikkoth Balakrishna, Frank Eisenhaber, Neelagandan Kamariah, Birgit Eisenhaber, Gerhard Grüber
Publikováno v:
Free Radical Biology and Medicine
The vancomycin-resistant Enterococcus faecalis alkyl hydroperoxide reductase complex (AhpR) with its subunits AhpC (EfAhpC) and AhpF (EfAhpF) is of paramount importance to restore redox homeostasis. Therefore, knowledge about this defense system is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d88b3168a02ec309b48821ec7af6279
https://doi.org/10.1016/j.freeradbiomed.2019.04.036
https://doi.org/10.1016/j.freeradbiomed.2019.04.036
Publikováno v:
Free Radical Biology and Medicine. 118:59-70
Peroxiredoxins (Prxs) catalyse the rapid reduction of hydrogen peroxide, organic hydroperoxide and peroxynitrite, using a fully conserved peroxidatic cysteine (CP) located in a conserved sequence Pxxx(T/S)xxCP motif known as CP-loop. In addition, Prx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f7485029c1073a42363c27bd0d8304
https://doi.org/10.1016/j.freeradbiomed.2018.02.027
https://doi.org/10.1016/j.freeradbiomed.2018.02.027
Autor:
Vikrant Kumar, Bryn Hardwick, Saranya Giridharan, Sneha Sudhakar, Markus Muellner, Manjunath A. Hurakadli, Ashok R. Venkitaraman, Gayathri Sadasivam, T.K. Prasad, Neelagandan Kamariah, Grahame J. McKenzie, Alex T. Crooks, Subashini Mathivanan, Paul M. Watt, Miguel Coelho, Sneha Bairy, Nadia Milech, Chandan Mithra, Christopher J. Torrance, Amy Emery, Kavitha Bharatham
Publikováno v:
Cell Chemical Biology
Summary Genetic screening technologies to identify and validate macromolecular interactions (MMIs) essential for complex pathways remain an important unmet need for systems biology and therapeutics development. Here, we use a library of peptides from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82261f81e78bea18e12f385b6c100941
https://doi.org/10.1016/j.chembiol.2021.05.009
https://doi.org/10.1016/j.chembiol.2021.05.009
Autor:
Neelagandan, Kamariah, Roland G, Huber, Wilson, Nartey, Shashi, Bhushan, Peter J, Bond, Gerhard, Grüber
Publikováno v:
Journal of structural biology. 207(2)
In contrast to other prokaryotes, the Mycobacterial F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::addcefaa0c05aedc0161d55f8aa8af55
https://pubmed.ncbi.nlm.nih.gov/31132404
https://pubmed.ncbi.nlm.nih.gov/31132404