Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Neekun Sharma"'
Autor:
Chetan P. Hans, Neekun Sharma, Edward Downey, Jr., Menka Khoobchandani, Kavita Katti, Kattesh V. Katti
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 418-419 (2022)
Externí odkaz:
https://doaj.org/article/c25dcc8da1e44eddbc510b59266d786c
Autor:
Neekun Sharma, Chetan P. Hans
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 3 (2021)
Background Development of abdominal aortic aneurysm (AAA) is associated with proinflammatory cytokines including interleukin‐12 (IL12). Deficiency of interleukin 12p40 (IL12p40) increases localized fibrotic events by promoting TGFβ2 (transforming
Externí odkaz:
https://doaj.org/article/cfffc0e912c94a838e65b44e72ed5d7d
Autor:
Akitoyo Hotta, Neekun Sharma, Osamu Fujita, Akihiko Uda, Kiyoshi Tanabayashi, Deyu Tian, Akio Yamada, Shigeru Morikawa, Ken Maeda
Publikováno v:
Microorganisms, Vol 8, Iss 12, p 1881 (2020)
Francisella tularensis (F. tularensis) is the etiological agent of the zoonotic disease tularemia. F. tularensis subspecies holarctica biovar japonica has rarely been isolated in Japan and is considered to have moderate virulence, although the biolog
Externí odkaz:
https://doaj.org/article/439013b2276d4e1690cda9164a234565
Autor:
Akihiko Uda, Neekun Sharma, Kazuhiro Takimoto, Tian Deyu, Yuuki Koyama, Eun-Sil Park, Osamu Fujita, Akitoyo Hotta, Shigeru Morikawa
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159740 (2016)
Pullulanase, an enzyme that catalyzes the hydrolysis of polysaccharides, has been identified in a broad range of organisms, including bacteria, yeasts, fungi, and animals. The pullulanase (pulB; FTT_0412c) of F. tularensis subspecies tularensis Schu
Externí odkaz:
https://doaj.org/article/554b036ba05b449b9f4b1f53fc686cfd
Autor:
Akihiko Uda, Tsuyoshi Sekizuka, Kiyoshi Tanabayashi, Osamu Fujita, Makoto Kuroda, Akitoyo Hotta, Naoko Sugiura, Neekun Sharma, Shigeru Morikawa, Akio Yamada
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89075 (2014)
Francisella tularensis subspecies tularensis, the etiological agent of tularemia, is highly pathogenic to humans and animals. However, the SCHU strain of F. tularensis SCHU P0 maintained by passaging in artificial media has been found to be attenuate
Externí odkaz:
https://doaj.org/article/0f5d9151ba0d447db6e69230e176184c
Autor:
Camila Manrique-Acevedo, Rogerio N. Soares, James A. Smith, Lauren K. Park, Katherine Burr, Francisco I. Ramirez-Perez, Neil J. McMillan, Larissa Ferreira-Santos, Neekun Sharma, T. Dylan Olver, Craig A. Emter, Elizabeth J. Parks, Jacqueline K. Limberg, Luis A. Martinez-Lemus, Jaume Padilla
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R293-R304
Vascular insulin resistance, a major characteristic of obesity and type 2 diabetes (T2D), manifests with blunting of insulin-induced vasodilation. Although there is evidence that females are more whole body insulin sensitive than males in the healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6cc608667930643d3fee84de17e81c
https://doi.org/10.1152/ajpregu.00249.2022
https://doi.org/10.1152/ajpregu.00249.2022
Autor:
Thomas J. Jurrissen, Francisco I. Ramirez-Perez, Francisco J. Cabral-Amador, Rogerio N. Soares, Ryan J. Pettit-Mee, Edgar E. Betancourt-Cortes, Neil J. McMillan, Neekun Sharma, Helena N. M. Rocha, Shumpei Fujie, Mariana Morales-Quinones, Yoskaly Lazo-Fernandez, Andrew A. Butler, Subhashis Banerjee, Harold S. Sacks, Jamal A. Ibdah, Elizabeth J. Parks, R. Scott Rector, Camila Manrique-Acevedo, Luis A. Martinez-Lemus, Jaume Padilla
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H879-H891
Adropin is a peptide largely secreted by the liver and known to regulate energy homeostasis; however, it also exerts cardiovascular effects. Herein, we tested the hypothesis that low circulating levels of adropin in obesity and type 2 diabetes (T2D)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7064f696e54b677f7e59ffa567c26a2c
https://doi.org/10.1152/ajpheart.00385.2022
https://doi.org/10.1152/ajpheart.00385.2022
Autor:
Ryan J. Pettit-Mee, Gavin Power, Francisco J. Cabral-Amador, Francisco I. Ramirez-Perez, Rogerio N. Soares, Neekun Sharma, Ying Liu, Demetra D. Christou, Jill A. Kanaley, Luis A. Martinez-Lemus, Camila Manrique-Acevedo, Jaume Padilla
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Impaired endothelial insulin signaling and consequent blunting of insulin-induced vasodilation is a feature of type 2 diabetes (T2D) that contributes to vascular disease and glycemic dysregulation. However, the molecular mechanisms underlying endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a1579077331c2207c0033666d5a3ad
https://doi.org/10.1152/ajpregu.00006.2022
https://doi.org/10.1152/ajpregu.00006.2022
Autor:
Olubodun Lateef, Francisco Ramirez-Perez, Neekun Sharma, Christopher Foote, Thomas Jurrisen, Gavin Power, Mariana Morales-Quinones, Edgar Betancourt-Cortes, Larissa Ferreira-Santos, Yoskaly Lazo-Fernandez, Marc Augenreich, Camila Manrique-Acevedo, Jaume Padilla, Luis Martinez-Lemus
Publikováno v:
Physiology. 38
The vascular glycocalyx, in particular, that which protrudes from the endothelium into the vascular lumen, is an important player in multiple functions of blood vessels. The glycocalyx is a mesh of glycoproteins and proteoglycans present on the outer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37d4491f3c0717a3a0333a491068a5de
https://doi.org/10.1152/physiol.2023.38.s1.5795537
https://doi.org/10.1152/physiol.2023.38.s1.5795537
Autor:
Neekun Sharma, Francisco Ramirez-Perez, Edgar Betancourt-Cortes, Gavin Power, Yoskaly Lazo-Fernandez, Luis Alejandro Martinez-Lemus, Jaume Padilla, Camila Manrique
Publikováno v:
Physiology. 38
Arterial stiffening and endothelial dysfunction are key contributors to the development and progression of cardiovascular disease (CVD) in women with obesity. Estrogen actions in the vasculature, mainly mediated via estrogen receptor alpha (ERα), re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba6cbb8e726a3a12d98ec0ee4ea7043
https://doi.org/10.1152/physiol.2023.38.s1.5734981
https://doi.org/10.1152/physiol.2023.38.s1.5734981