Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Needham EJ"'
Autor:
Needham, EJ, Ren, AL, Digby, RJ, Norton, EJ, Ebrahimi, S, Outtrim, JG, Chatfield, DA, Manktelow, AE, Leibowitz, MM, Newcombe, VFJ, Doffinger, R, Barcenas-Morales, G, Fonseca, C, Taussig, MJ, Burnstein, RM, Samanta, RJ, Dunai, C, Sithole, N, Ashton, NJ, Zetterberg, H, Gisslén, M, Edén, A, Marklund, E, Openshaw, PJM, Dunning, J, Griffiths, MJ, Cavanagh, J, Breen, G, Irani, SR, Elmer, A, Kingston, N, Summers, C, Bradley, JR, Taams, LS, Michael, BD, Bullmore, ET, Smith, KGC, Lyons, PA, Coles, AJ, Menon, DK, Cambridge NeuroCOVID Group the CITIID-NIHR COVID-19 BioResource Collaboration and Cambridge NIHR Clinical Research Facility
Publikováno v:
Needham, E J, Ren, A L, Digby, R J, Norton, E J, Ebrahimi, S, Outtrim, J G, Chatfield, D A, Manktelow, A E, Leibowitz, M M, Newcombe, V F J, Doffinger, R, Barcenas-Morales, G, Fonseca, C, Taussig, M J, Burnstein, R M, Samanta, R J, Dunai, C, Sithole, N, Ashton, N J, Zetterberg, H, Gisslén, M, Edén, A, Marklund, E, Openshaw, P J M, Dunning, J, Griffiths, M J, Cavanagh, J, Breen, G, Irani, S R, Elmer, A, Kingston, N, Summers, C, Bradley, J R, Taams, L S, Michael, B D, Bullmore, E T, Smith, K G C, Lyons, P A, Coles, A J & Menon, D K 2022, ' Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses ', Brain research, pp. awac321 . https://doi.org/10.1093/brain/awac321
COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19 severity. The true frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3b4f8b8d62eaefb16e3088e5633685
https://doi.org/10.1093/brain/awac321
https://doi.org/10.1093/brain/awac321
Autor:
Havula, E, Ghazanfar, S, Lamichane, N, Francis, D, Hasygar, K, Liu, Y, Alton, LA, Johnstone, J, Needham, EJ, Pulpitel, T, Clark, T, Niranjan, HN, Shang, V, Tong, V, Jiwnani, N, Audia, G, Alves, AN, Sylow, L, Mirth, C, Neely, GG, Yang, J, Hietakangas, V, Simpson, SJ, Senior, AM
Publikováno v:
Havula, E, Ghazanfar, S, Lamichane, N, Francis, D, Hasygar, K, Liu, Y, Alton, L A, Johnstone, J, Needham, E J, Pulpitel, T, Clark, T, Niranjan, H N, Shang, V, Tong, V, Jiwnani, N, Audia, G, Alves, A N, Sylow, L, Mirth, C, Neely, G G, Yang, J, Hietakangas, V, Simpson, S J & Senior, A M 2022, ' Genetic variation of macronutrient tolerance in Drosophila melanogaster ', Nature Communications, vol. 13, 1637 . https://doi.org/10.1038/s41467-022-29183-x
Carbohydrates, proteins and lipids are essential nutrients to all animals; however, closely related species, populations, and individuals can display dramatic variation in diet. Here we explore the variation in macronutrient tolerance in Drosophila m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57106e5d9fd9dd46043a1dc8e712639e
Autor:
Needham, EJ, Ren, AL, Digby, RJ, Outtrim, JG, Chatfield, DA, Manktelow, AE, Newcombe, VFJ, Doffinger, R, Barcenas-Morales, G, Fonseca, C, Taussig, MJ, Burnstein, RM, Dunai, C, Sithole, N, Ashton, NJ, Zetterberg, H, Gisslen, M, Edén, A, Marklund, E, Griffiths, MJ, Cavanagh, J, Breen, G, Irani, Elmer, A, Kingston, N, Bradley, Taams, LS, Michael, BD, Bullmore, ET, Smith, KGC, Lyons, PA, Coles, AJC, Menon, DK, Group, The Cambridge NeuroCOVID, BioResource, The NIHR COVID-19, Cambridge NIHR Clinical Research Facility
COVID-19 has been associated with many neurological complications including stroke, delirium and encephalitis. Furthermore, many individuals experience a protracted post-viral syndrome which is dominated by neuropsychiatric symptoms, and is seemingly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60833cf34978f409156539af2b35fad
https://www.repository.cam.ac.uk/handle/1810/343727
https://www.repository.cam.ac.uk/handle/1810/343727
Autor:
C. Domínguez Conde, C. Xu, L. B. Jarvis, D. B. Rainbow, S. B. Wells, T. Gomes, S. K. Howlett, O. Suchanek, K. Polanski, H. W. King, L. Mamanova, N. Huang, P. A. Szabo, L. Richardson, L. Bolt, E. S. Fasouli, K. T. Mahbubani, M. Prete, L. Tuck, N. Richoz, Z. K. Tuong, L. Campos, H. S. Mousa, E. J. Needham, S. Pritchard, T. Li, R. Elmentaite, J. Park, E. Rahmani, D. Chen, D. K. Menon, O. A. Bayraktar, L. K. James, K. B. Meyer, N. Yosef, M. R. Clatworthy, P. A. Sims, D. L. Farber, K. Saeb-Parsy, J. L. Jones, S. A. Teichmann
Publikováno v:
Science
Despite their crucial role in health and disease, our knowledge of immune cells within human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 adult donors by single-cell RNA sequencing and VDJ sequencing generating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b485705daf8e4470b5b527507195036
https://www.repository.cam.ac.uk/handle/1810/338057
https://www.repository.cam.ac.uk/handle/1810/338057
Publikováno v:
Journal of Neurology
Coronavirus Disease 2019 is predominantly a disorder of the respiratory system, but neurological complications have been recognised since early in the pandemic. The major pathophysiological processes leading to neurological damage in COVID-19 are cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f64217cce327c6ed33e28a9fb397e4
Autor:
Kristensen JM; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Kjøbsted R; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Larsen TJ; Greenland Center of Health Research, Institute of Institute of Health and Nature, University of Greenland, Nuuk, Greenland., Carl CS; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Hingst JR; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Onslev J; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Birk JB; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Thorup A; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Steenberg DE; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Knudsen JR; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Henriksen NS; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Needham EJ; Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., Halling JF; Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Gudiksen A; Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Rundsten CF; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hanghøj KE; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Stinson SE; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hoier B; August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Hansen CC; August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Jensen TE; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Hellsten Y; August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Pilegaard H; Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Olesen J; Queen Ingrid Primary Health Care Center, Nuuk, Greenland., Humphrey SJ; Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia., James DE; Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia., Pedersen ML; Greenland Center of Health Research, Institute of Institute of Health and Nature, University of Greenland, Nuuk, Greenland.; Steno Diabetes Center Greenland, Nuuk, Greenland., Richter EA; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jørgensen ME; Greenland Center of Health Research, Institute of Institute of Health and Nature, University of Greenland, Nuuk, Greenland.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; National Institute of Public Health, University of Southern Denmark, Odense, Denmark., Wojtaszewski JFP; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. jw@nexs.ku.dk.
Publikováno v:
Nature metabolism [Nat Metab] 2024 Oct 31. Date of Electronic Publication: 2024 Oct 31.
Autor:
Dunai C; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Hetherington C; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Boardman SA; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Clark JJ; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Sharma P; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Subramaniam K; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Tharmaratnam K; Department of Health Data Science, Institute of Population Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom., Needham EJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Williams R; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom., Huang Y; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Wood GK; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Collie C; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Fower A; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom., Fox H; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom., Ellul MA; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Held M; Centre for Cell Imaging, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom., Egbe FN; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Griffiths M; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom., Solomon T; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom.; Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom., Breen G; Department of Social, Genetic & Developmental Psychiatry Centre, School of Mental Health & Psychological Sciences, King's College London, London, United Kingdom.; NIHR Maudsley Biomedical Research Centre, King's College London, London, United Kingdom., Kipar A; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland., Cavanagh J; College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Irani SR; Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom., Vincent A; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom., Stewart JP; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Taams LS; Centre for Inflammation Biology and Cancer Immunology, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Menon DK; Division of Anaesthesia, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom., Michael BD; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.; Clinical Infection Microbiology and Immunology, Institute of Infection Ecology and Veterinary Sciences, University of Liverpool, Liverpool, United Kingdom.; Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2024 Oct 14; Vol. 15, pp. 1440324. Date of Electronic Publication: 2024 Oct 14 (Print Publication: 2024).
Autor:
Dooley J; Department of Pathology, University of Cambridge, Cambridge, UK. jd2045@cam.ac.uk., Hughes JG; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK., Needham EJ; Department of Clinical Neuroscience, University of Cambridge, Cambridge, UK., Palios KA; Department of Pathology, University of Cambridge, Cambridge, UK., Liston A; Department of Pathology, University of Cambridge, Cambridge, UK.
Publikováno v:
Journal of neuroinflammation [J Neuroinflammation] 2024 Jul 28; Vol. 21 (1), pp. 183. Date of Electronic Publication: 2024 Jul 28.
Autor:
Coppard V; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Szep G; Randall Centre for Cell & Molecular Biophysics, King's College London, London, United Kingdom., Georgieva Z; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Howlett SK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Jarvis LB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Rainbow DB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Suchanek O; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Needham EJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Mousa HS; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Menon DK; Department of Anaesthesia, University of Cambridge, Cambridge, United Kingdom., Feyertag F; Independent Researcher, Oxford, United Kingdom., Mahbubani KT; Department of Surgery, University of Cambridge, Cambridge, United Kingdom.; Collaborative Biorepository for Translational Medicine (CBTM), Cambridge NIHR Biomedical Research Centre, Cambridge, United Kingdom., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, United Kingdom.; Collaborative Biorepository for Translational Medicine (CBTM), Cambridge NIHR Biomedical Research Centre, Cambridge, United Kingdom., Jones JL; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2024 Jul 17; Vol. 15, pp. 1425488. Date of Electronic Publication: 2024 Jul 17 (Print Publication: 2024).
Autor:
Greene SM; Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78712, USA., Schachat SR; Entomology Section, Department of Plant and Environmental Sciences, The University of Hawai'i at Mānoa, Honolulu, Hawai'i 96822, USA., Arita-Merino N; Sustainable Food Processing Laboratory, Institute of Food, Nutrition and Health, ETH Zürich, 8092 Zürich, Switzerland., Cao XE; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Gurnani H; Department of Biology, University of Washington, Seattle, WA, USA., Heyns M; Blackett Laboratory, Imperial College London, London, UK., Cagigas ML; Sydney Medical School Nepean, University of Sydney, Sydney, NSW, Australia., Maikawa CL; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Needham EJ; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Perets EA; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Phillips E; Inorganic Chemistry Laboratory, University of Oxford, Oxford, UK., Waddle AW; Applied Biosciences, Macquarie University, Sydney, NSW 2109, Australia., Wilkinson CE; Department of Environmental Science, Policy, and Management, University of California, Berkeley, Berkeley, CA, USA.; California Academy of Sciences, San Francisco, CA, USA., Zhou KC; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA., Zlotnick HM; BioFrontiers Institute, University of Colorado, Boulder, CO 80303, USA.
Publikováno v:
IScience [iScience] 2024 Jun 26; Vol. 27 (7), pp. 110220. Date of Electronic Publication: 2024 Jun 26 (Print Publication: 2024).