Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Nediljko Budisa"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/2d203ff709964ba480da3f5d992eb5cc
Autor:
Huan Sun, Haiyang Jia, Olivia Kendall, Jovan Dragelj, Vladimir Kubyshkin, Tobias Baumann, Maria-Andrea Mroginski, Petra Schwille, Nediljko Budisa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Sun et al. has studied the genetically encodable halotyrosines in proteins of the prokaryotic cell division machinery to elucidate the general role of halogenation in cellular lifespan and oxidative damage-induced diseases such as aging and cancer.
Externí odkaz:
https://doaj.org/article/16c257434def474fb0e926ce48e5732a
Autor:
Minkoo Ahn, Tomasz Włodarski, Alkistis Mitropoulou, Sammy H. S. Chan, Haneesh Sidhu, Elena Plessa, Thomas A. Becker, Nediljko Budisa, Christopher A. Waudby, Roland Beckmann, Anaïs M. E. Cassaignau, Lisa D. Cabrita, John Christodoulou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The narrow exit tunnel of the ribosome is important for cotranslational protein folding. Here, authors show that their rationally designed and engineered exit tunnel protein loops modulate the free energy of nascent chain dynamics and folding.
Externí odkaz:
https://doaj.org/article/cea56fc2e4f24b7ba30039a8d7fd533e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14035 (2023)
All known organisms encode 20 canonical amino acids by base triplets in the genetic code. The cellular translational machinery produces proteins consisting mainly of these amino acids. Several hundred natural amino acids serve important functions in
Externí odkaz:
https://doaj.org/article/71880b2d7cf640df9c59654b9ef5cce9
Autor:
Marcus Moldenhauer, Hsueh-Wei Tseng, Anastasia Kraskov, Neslihan N. Tavraz, Igor A. Yaroshevich, Peter Hildebrandt, Nikolai N. Sluchanko, Georg A. Hochberg, Lars-Oliver Essen, Nediljko Budisa, Lukas Korf, Eugene G. Maksimov, Thomas Friedrich
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Dissecting the intricate networks of covalent and non-covalent interactions that stabilize complex protein structures is notoriously difficult and requires subtle atomic-level exchanges to precisely affect local chemical functionality.
Externí odkaz:
https://doaj.org/article/6ed6139269b24933818f17479db45d3c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Across scales, many biological phenomena, such as protein folding or bioadhesion and cohesion, rely on synergistic effects of different amino acid side chains at multiple positions in the protein sequence. These are often fine-tuned by post-translati
Externí odkaz:
https://doaj.org/article/1910a78928a34f338d30f72788989478
Autor:
Erhan Deniz, Luis Valiño-Borau, Jan G. Löffler, Katharina B. Eberl, Adnan Gulzar, Steffen Wolf, Patrick M. Durkin, Robert Kaml, Nediljko Budisa, Gerhard Stock, Jens Bredenbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Vibrational energy transfer (VET) is essential for protein function as it is responsible for efficient energy dissipation in reaction sites and is linked to pathways of allosteric communication. Here authors equipped a tryptophan zipper with a VET in
Externí odkaz:
https://doaj.org/article/61744375dbee47668eb67fc4afc0bb9f
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 439-460 (2021)
Due to the heterocyclic structure and distinct conformational profile, proline is unique in the repertoire of the 20 amino acids coded into proteins. Here, we summarize the biochemical work on the replacement of proline with (4R)- and (4S)-fluoroprol
Externí odkaz:
https://doaj.org/article/4c0bc3479cd64ad98675c9a7ea0673c6
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4501 (2023)
Although many bacterial lipases and PHA depolymerases have been identified, cloned, and characterized, there is very little information on the potential application of lipases and PHA depolymerases, especially intracellular enzymes, for the degradati
Externí odkaz:
https://doaj.org/article/dff1ac2b093b49ff8ce63f3a9169fb56
Autor:
Federica Agostini, Ludwig Sinn, Daniel Petras, Christian J. Schipp, Vladimir Kubyshkin, Allison Ann Berger, Pieter C. Dorrestein, Juri Rappsilber, Nediljko Budisa, Beate Koksch
Publikováno v:
ACS Central Science, Vol 7, Iss 1, Pp 81-92 (2020)
Externí odkaz:
https://doaj.org/article/f25c840e9c8042a2ae6989f1c3079b99