Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nedda Wilson"'
Autor:
Lisa M. Roth, Donna L. Herber, Nedda Wilson, Keisha Symmonds, Melissa J. Freeman, Marcia N. Gordon, Jessica L. Maloney, Dave Morgan, Mary Mercer
Publikováno v:
Journal of Neuroimmune Pharmacology. 2:222-231
Inflammation has been argued to play a fundamental role in the pathogenesis of Alzheimer's disease. Mice transgenic for mutant human amyloid precursor protein (APP) develop progressive amyloid deposition, gliosis, and cognitive impairment. Paradoxica
Autor:
Sangeetha Subbarao, Arnon Rosenthal, Nedda Wilson, Jennifer Alamed, Donna M. Wilcock, David Wilson, Gil Levkowitz, Melissa J. Freeman, Amyn M. Rojiani, Dave Morgan, Marcia N. Gordon
Publikováno v:
The Journal of Neuroscience. 24:6144-6151
The role of microglia in the removal of amyloid deposits after systemically administered anti-Abeta antibodies remains unclear. In the current study, we injected Tg2576 APP transgenic mice weekly with an anti-Abeta antibody for 1, 2, or 3 months such
Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice
Autor:
David M. Diamond, Chad A. Dickey, Nedda Wilson, John F. Guzowski, Dave Morgan, Marcia N. Gordon, Jerimiah E. Mason
Publikováno v:
Journal of Neurochemistry. 88:434-442
Mice transgenic for mutated forms of the amyloid precursor protein (APP) plus presenilin-1 (PS1) genes (APP + PS1 mice) gradually develop memory deficits which correlate with the extent of amyloid deposition. The expression of several immediate-early
Autor:
Lisa M. Roth, Donna L. Herber, Nedda Wilson, Marcia N. Gordon, Jerimiah E. Mason, Dave Morgan, David Wilson
Publikováno v:
Experimental neurology. 190(1)
Inflammation has been argued to play a primary role in the pathogenesis of Alzheimer's disease (AD). Lipopolysaccharide (LPS) activates the innate immune system, triggering gliosis and inflammation when injected in the central nervous system. In stud
Autor:
Donna M. Wilcock, Melissa J. Freeman, Jennifer Alamed, Amyn M. Rojiani, Nedda Wilson, David M. Wilson, Arnon Rosenthal, Marcia N. Gordon, Dave Morgan
Publikováno v:
Neurobiology of Aging. 25:S579