Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nedathur Narasimhachari"'
Autor:
Jos Domen, John J. Ryan, Daniel P. Bailey, Christopher P. Shelburne, Jennifer K. Stewart, Nathalie Simeon, Nedathur Narasimhachari, Jessica G. Freeman, L.Andrew Bouton, François Couderc
Publikováno v:
Journal of Neuroimmunology. 119:231-238
Cultured murine bone marrow derived mast cells (BMMC) were found to store high levels of dopamine (3753+/-844 pg/10(7) cells) and occasionally produce norepinephrine and epinephrine. The catecholamine synthesis inhibitor, alpha-methyl-para-tyrosine,
Publikováno v:
Neurochemistry International. 24:183-189
Brain catecholamine levels, spinal cord levels of the norepinephrine metabolite methoxy-hydroxy-phenylglycol (MHPG), and heart rate were measured in nondiabetic and streptozocin-diabetic rats after sham surgery or bilateral carotid ligation. Although
Autor:
Randall T Meyers, Scott W Brown, Jennifer K. Stewart, Karen M Brennan, John J. Ryan, Nedathur Narasimhachari, Edmund F Perozzi, Julie M Rumble, Krista Fischer-Stenger
Publikováno v:
Journal of neuroimmunology. 135(1-2)
This study provides the first evidence for catecholamine synthesis and release in the RAW264.7 cell line, an important macrophage model. Although catecholamines were low in unstimulated cells, activation with lipopolysaccharide (LPS) induced tyrosine
Publikováno v:
Brain research. 739(1-2)
Although alpha-methyl-L-p-tyrosine (alpha-MPT), an inhibitor of catecholamine synthesis, has been used to study catecholamine turnover in diabetic animals, effects of diabetes on metabolism of the drug have not been investigated. In this study, admin
Publikováno v:
European Journal of Pharmacology. 139:193-204
Acute morphine produced a dose-dependent, naloxone-sensitive, reversible increase in tryptophan hydroxylase activity in low speed supernatants of midbrain, pons-medulla and cerebral cortex but not spinal cord. The increase in cortical enzyme activity
Publikováno v:
Biochemical Pharmacology. 32:185-188
Autor:
Nedathur Narasimhachari
Publikováno v:
Journal of Liquid Chromatography. 9:2223-2235
A micromethod for the quantitation of tryptophan in biological fluids, such as whole blood, RBC, serum, plasma or tissue homogenates using HPLC and electrochemical detection is described. -Methyl tryptophan is used as an internal standard. Ten microl
Autor:
Nedathur Narasimhachari
Publikováno v:
Journal of Liquid Chromatography. 7:2679-2689
A simple method for sample clean up and concentration of serotonin (5-HT) in biological samples, such as human cerebro-spinal fluid and serum, is described. To the sample 6-hydroxy-tryptamine (6-HT) is added as an internal standard and it is then abs
Publikováno v:
Journal of Liquid Chromatography. 11:983-989
A simple HPLC method is described for the quantitation of molindone in human serum or plasma using trazadone as an internal standard and UV detection (247 nm). The method was successfully used to determine the steady state levels of molindone in 15 p
Publikováno v:
Journal of Liquid Chromatography. 10:2439-2446
A refined HPLC Method for the determination of monoamine levels in six brain regions is presented. Analyses are made for the olfactory tubercles, prefrontal cortex, septum, striatum, amygdala and hypothalamus of adult male ICR mice. This system permi