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pro vyhledávání: '"Neda Assareh"'
Publikováno v:
Cannabis Cannabinoid Res
INTRODUCTION: Medicinal cannabis has proliferated around the world and there is increasing interest in the therapeutic potential of individual plant-derived cannabinoids (phytocannabinoids). Preclinical evidence suggests the phytocannabinoid cannabig
Publikováno v:
Behavioural pharmacology. 31(6)
The major phytocannabinoid cannabidiol (CBD) has anxiolytic properties and lacks tetrahydrocannabinol-like psychoactivity. Cannabidiolic acid (CBDA) is the acidic precursor to CBD, and this compound appears more potent than CBD in animal models of em
Publikováno v:
Neurobiology of Learning and Memory. 144:186-197
The midbrain periaqueductal gray (PAG) has been implicated in the generation and transmission of a prediction error signal that instructs amygdala-based fear and extinction learning. However, the PAG also plays a key role in the expression of conditi
Publikováno v:
Behavioral Neuroscience. 130:406-414
Rodents display characteristic defense responses to predators that are influenced by predatory imminence. The midbrain periaqueductal gray (PAG) serves an important role controlling these responses. The most influential model states that variations i
Publikováno v:
Behavioral neuroscience. 131(6)
The midbrain periaqueductal gray (PAG) coordinates the expression and topography of defensive behaviors to threat and also plays an important role in Pavlovian fear learning itself. Whereas the role of PAG in expression of defensive behavior is well
Publikováno v:
Pharmacology Biochemistry and Behavior. 100:506-512
Recent findings indicate that CB1 receptor blockade might be relevant to the action of antidepressant drugs as inhibition of endocannabinoid function can increase synaptic availability of neurotransmitters; an effect also seen with chronic antidepres
Publikováno v:
Psychopharmacology. 221:239-247
Several pre-clinical and human-based studies have shown that acutely administered cannabidiol (CBD) can produce anxiolytic-like effects The present study investigated the effects of chronic administration of CBD on rat behaviour and on the expression
Publikováno v:
Psychopharmacology. 222:727-727
In reply to Dr. Gururajan's comments on our manuscript (Elbatsh et al. 2012) about the anxiogenic-like effects of chronic cannabidiol administration in rats, we accept that the use of a wider ranging dose/response design would have been desirable. We
Publikováno v:
BMC Psychiatry
BMC Psychiatry, Vol 11, Iss 1, p 131 (2011)
BMC Psychiatry, Vol 11, Iss 1, p 131 (2011)
Background Several computerised cognitive behaviour therapy (cCBT) packages are now available to treat mild to moderate depression with or without anxiety. These have been usually been reviewed alongside cCBT for a wide range of psychological problem