Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ned Watson"'
Publikováno v:
European Journal of Biochemistry. 124:553-559
A new endoribonuclease activity, RNase F, was partially purified from Escherichia coli cells. This activity can specifically cleave a precursor RNA molecule (of species 1) isolated from T4-infected cells [N. Watson & D. Apirion (1981) Biochem. Biophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9496939e7825d3e1dc05c48814a6c6
https://doi.org/10.1111/j.1432-1033.1982.tb06629.x
https://doi.org/10.1111/j.1432-1033.1982.tb06629.x
Autor:
Richard J. Mehigh, Ned Watson, Graham B. I. Scott, Rebecca Davis, John G. Dapron, Michael C. Harvey, Dian Er Chen
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbfc0bff77f71375cbcf107c75238c72
https://doi.org/10.1096/fasebj.20.5.a927
https://doi.org/10.1096/fasebj.20.5.a927
Autor:
Anthony J. Muslin, Jeffrey N. Rottman, Ned Watson, Joseph E. Zahner, Kendall J. Blumer, Shaosong Zhang
Publikováno v:
Journal of molecular and cellular cardiology. 30(2)
RGS family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes when t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4e8a9835fcbca10863662d7aeca973
https://pubmed.ncbi.nlm.nih.gov/9515003
https://pubmed.ncbi.nlm.nih.gov/9515003
Publikováno v:
The Journal of biological chemistry. 273(3)
GTP hydrolysis by guanine nucleotide-binding proteins, an essential step in many biological processes, is stimulated by GTPase-activating proteins (GAPs). The mechanisms whereby GAPs stimulate GTP hydrolysis are unknown. We have used mutational, bioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1ef597de71a27959adede648248914
https://pubmed.ncbi.nlm.nih.gov/9430692
https://pubmed.ncbi.nlm.nih.gov/9430692
RGS ( r egulators of G protein s ignaling) proteins are GTPase activating proteins that inhibit signaling by heterotrimeric G proteins. All RGS proteins studied to date act on members of the Giα family, but not Gsα or G12α. RGS4 regulates Giα fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4901b43e0f5cf2baeed57c2f301c7e5d
https://europepmc.org/articles/PMC24991/
https://europepmc.org/articles/PMC24991/
Publikováno v:
Nature. 383(6596)
Signaling pathways using heterotrimeric guanine-nucleotide-binding-proteins (G proteins) trigger physiological responses elicited by hormones, neurotransmitters and sensory stimuli. GTP binding activates G proteins by dissociating G alpha from G beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f98becebbcd32729432b781e481ab12
https://pubmed.ncbi.nlm.nih.gov/8774882
https://pubmed.ncbi.nlm.nih.gov/8774882
Autor:
Eric Olson, Ned Watson
Publikováno v:
Gene. 86(2)
The bGH cDNA coding for bovine growth hormone (bGH) is expressed poorly in Escherichia coli using a pBR322-based expression plasmid. Random mutagenesis of the plasmid gave rise to two types of plasmid mutants which increased the expression of bGH. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073a9c8ed9035b7016812c934aaf8e2b
https://pubmed.ncbi.nlm.nih.gov/2182388
https://pubmed.ncbi.nlm.nih.gov/2182388
Autor:
Ned Watson, David Apirion
Publikováno v:
Molecular and General Genetics MGG. 136:317-326
Pairs of very closely related Escherichia coli strains were prepared, one having the wild-type allele for ribonuclease III, an enzyme which specifically degrades double-stranded RNA, and the other having a mutant RNase III allele. Growth and phage pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeb71468c97399323880376cae25f1c
https://doi.org/10.1007/bf00341716
https://doi.org/10.1007/bf00341716
Publikováno v:
Genetics. 90:19-35
To determine if proteins RNase III and rho, both of which can determine the 3' ends of RNA molecules, can complement each other, double mutants defective in these two factors were constructed. In all cases (four rho mutations tested) the double mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55feadfcbb309401ceede1c03c042243
https://doi.org/10.1093/genetics/90.1.19
https://doi.org/10.1093/genetics/90.1.19
Publikováno v:
Molecular and General Genetics MGG. 144:185-190
An isogenic pair of Escherichia coli strains, one carrying an rnc+ and the other an rnc- allele (a mutation which reduces the level of ribonuclease III), was compared. The rnc- strain fails to grow at very elevated temperatures (for E. coli) while th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4146843ded7362050938c3023191b978
https://doi.org/10.1007/bf02428107
https://doi.org/10.1007/bf02428107