Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Necroptotic signaling pathway"'
Autor:
Xinrong Tao, Aowei Mo, Lelin Hu, Min Mu, Luocheng Shao, Huihui Tao, Jing Wu, Jianhua Wang, Deyong Ge, Keyi Xu, Bin Li, Jinjun Liao, Hui Zhao
Publikováno v:
Toxicology Letters. 355:150-159
Silicosis is a disease characterized by extensive lung nodules and fibrosis caused by the prolonged inhalation of silica in occupational settings. However, the molecular mechanism of silicosis development is complex and not fully understood. Furtherm
Autor:
Zhichu Ren, Ji Heon Noh, Evandro Fei Fang, Libin Wei, Jialin Wu, Yong U Liu, Jian Sima, Yuyuan Yao, Xijing Chen, Yiqun Wu, Chong Xu, Guobing Chen
Publikováno v:
Theranostics
Background: Neuronal death is a major hallmark of Alzheimer's disease (AD). Necroptosis, as a programmed necrotic process, is activated in AD. However, what signals and factors initiate necroptosis in AD is largely unknown. Methods: We examined the e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
As a programmed necrotic cell death, necroptosis has the intrinsic initiators, including receptor-interacting serine/threonine-protein kinase 1 (RIPK1), RIPK3 and mixed-lineage kinase domain-like protein (MLKL), which combine to form necroptotic sign
Autor:
Shengyong Yang, Rong Xiang, Hui Li, Chengyong Wu, Kai Chen, Yiguo Hu, Yu Xiong, Liting Zhang, Shile Huang, Yangyang Cui, Yuquan Wei, Lin-Li Li, Qiuyuan Yang
Publikováno v:
Cell Death Differ
Necroptosis is a programmed form of necrotic cell death, which is tightly regulated by the necroptotic signaling pathway containing receptor-interacting protein (RIP)1, RIP3, and mixed-lineage kinase domain-like (MLKL) protein. In addition to the RIP
Necroptosis is a form of programmed necrotic cell death mediated by the kinase RIPK3 and its substrate MLKL. MLKL, which displays plasma membrane (PM) pore-forming activity upon phosphorylation, functions as the executioner during necroptosis. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba1804b94c6311346a9728e30db4612
Autor:
James M. Murphy, John Silke
Publikováno v:
EMBO reports. 15:155-164
When our time comes to die most people would probably opt for a quick, peaceful and painless exit. But the manner and timing are rarely under our direct control. Hence the Ars moriendi, literally, “The Art of Dying”, two texts written in Latin ar
Publikováno v:
Cell Death & Disease
Neurodegenerative diseases are a group of chronic progressive disorders characterized by neuronal loss. Necroptosis, a recently discovered form of programmed cell death, is a cell death mechanism that has necrosis-like morphological characteristics.