Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Necola Guerrina"'
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor expressed in the lungs that is activated by numerous xenobiotic, endogenous and dietary ligands. Although historically the AhR is known for mediating the deleterious respo
Externí odkaz:
https://doaj.org/article/d7860a1a314f4a1da40fc85c714a4db2
Autor:
Michela Zago, Jared A Sheridan, Hussein Traboulsi, Emelia Hecht, Yelu Zhang, Necola Guerrina, Jason Matthews, Parameswaran Nair, David H Eidelman, Qutayba Hamid, Carolyn J Baglole
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180881 (2017)
Heightened inflammation, including expression of COX-2, is associated with chronic obstructive pulmonary disease (COPD) pathogenesis. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is reduced in COPD-derived lung
Externí odkaz:
https://doaj.org/article/b0d4094b0b3749f1bfb687932d46ba5a
Autor:
Kashmira Prasade, Jason Matthews, Fangyi Shi, Hussein Traboulsi, Necola Guerrina, Noof Aloufi, David H. Eidelman, Carolyn J. Baglole, Qutayba Hamid, Caitlin Mehrotra
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 320:L339-L355
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor whose physiological function is poorly understood. The AhR is highly expressed in barrier organs such as the skin, intestine, and lung. The lungs are continuously exposed
Autor:
Jean Bourbeau, Patricia J. Sime, Michela Zago, Wan C. Tan, M. Obeidat, Parameswaran Nair, Qutayba Hamid, Corry-Anke Brandsma, Annette Robichaud, Benjamin M. Smith, Thomas H. Thatcher, Angela Rico de Souza, Richard P. Phipps, David H. Eidelman, Andrea Benedetti, Don D. Sin, Yohan Bossé, Swati Pareek, Jun Ding, Leora Simon, Necola Guerrina, Carolyn J. Baglole, David C. Nickle, Hussein Traboulsi, Pei Z. Li
Publikováno v:
FASEB J
FASEB Journal, 35(3):21376. FEDERATION AMER SOC EXP BIOL
FASEB Journal, 35(3):21376. FEDERATION AMER SOC EXP BIOL
Emphysema, a component of chronic obstructive pulmonary disease (COPD), is characterized by irreversible alveolar destruction that results in a progressive decline in lung function. This alveolar destruction is caused by cigarette smoke, the most imp
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3882 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Much of what is known about the Aryl Hydrocarbon Receptor (AhR) centers on its ability to mediate the deleterious effects of the environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; dioxin). However, the AhR is both ubiquitously-expresse
Autor:
Carolyn J. Baglole, Jason Matthews, David H. Eidelman, Necola Guerrina, Michela Zago, Yelu Zhang, Emelia Hecht, Qutayba Hamid, Hussein Traboulsi, Parameswaran Nair, Jared A. Sheridan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180881 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180881 (2017)
Heightened inflammation, including expression of COX-2, is associated with chronic obstructive pulmonary disease (COPD) pathogenesis. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is reduced in COPD-derived lung
Autor:
Alvin Gomez, Angela Rico de Souza, Matthew Iu, Sarah Rogers, Michela Zago, Carolyn J. Baglole, Necola Guerrina, Jason Matthews
Publikováno v:
Scientific Reports
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically known for its toxic responses to man-made pollutants such as dioxin. More recently, the AhR has emerged as a suppressor of inflammation, oxidative stress and
Autor:
Matthew Iu, Parisa A. Ariya, Hussein Traboulsi, Necola Guerrina, Carolyn J. Baglole, Dusica Maysinger
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 243 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Air pollution of anthropogenic origin is largely from the combustion of biomass (e.g., wood), fossil fuels (e.g., cars and trucks), incinerators, landfills, agricultural activities and tobacco smoke. Air pollution is a complex mixture that varies in