Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Necla Birgül-İyison"'
Autor:
Ali Işbilir, Burcin Duan Sahbaz, Gunes Tuncgenc, Moritz Bünemann, Martin J. Lohse, Necla Birgül-Iyison
Publikováno v:
ACS Omega, Vol 5, Iss 50, Pp 32183-32194 (2020)
Externí odkaz:
https://doaj.org/article/458f81919f3b4d748f38b5ba62a470c2
Autor:
Ayaz Najafov, Tuncay Seker, Ipek Even, Gerta Hoxhaj, Osman Selvi, Duygu Esen Ozel, Ahmet Koman, Necla Birgül-İyison
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37013 (2012)
Wnt/β-catenin signalling pathway plays important roles in embryonic development and carcinogenesis. Overactivation of the pathway is one of the most common driving forces in major cancers such as colorectal and breast cancers. The downstream effecto
Externí odkaz:
https://doaj.org/article/209912e2be2441afa0af930f9b18ade5
Publikováno v:
The FEBS Journal. 288:2727-2745
The increasing human population, combined with low inefficiency and adverse effects of available pesticides, has magnified the urgent need of developing next-generation pesticides. Among the available approaches, strategies targeting invertebrate G p
Autor:
Ali Işbilir, Aida Shahraki, Berna Dogan, Serdar Durdagi, Necla Birgül-Iyison, Martin J. Lohse
Publikováno v:
Journal of Chemical Information and Modeling. 61:715-728
Insect neuropeptide receptors, including allatostatin receptor type C (AstR-C), a G protein-coupled receptor, are among the potential targets for designing next-generation pesticides that despite their importance in offering a new mode-of-action have
Autor:
Burcin Duan Sahbaz, Gunes Tuncgenc, Ali Işbilir, Moritz Bünemann, Martin J. Lohse, Necla Birgül-Iyison
Publikováno v:
ACS Omega, Vol 5, Iss 50, Pp 32183-32194 (2020)
G protein-coupled receptors (GPCRs) play a pivotal role in regulating key physiological events in all animal species. Recent advances in collective analysis of genes and proteins revealed numerous potential neuro-peptides and GPCRs from insect specie
Publikováno v:
Genomics. 112:4203-4207
Insect neuropeptides play a major role in the regulation of the physiological processes. Due to their versatile effects on the development of insects, their corresponding receptors, which are mostly G-protein coupled receptors, are considered as idea
Autor:
Timucin Avsar, Berna Dogan, Muge Didem Orhan, Seyma Calis, Serdar Durdagi, Busecan Aksoydan, Necla Birgül Iyison, Aida Shahraki, Kader Sahin
Publikováno v:
Molecular Informatics
In the current study, we used 7922 FDA approved small molecule drugs as well as compounds in clinical investigation from NIH's NPC database in our drug repurposing study. SARS‐CoV‐2 main protease as well as Spike protein/ACE2 targets were used in
Publikováno v:
Turkish neurosurgery. 31(6)
AIM We aimed to study the changes in the distribution of and the transcriptional levels associated with α4- and α7-subtype nicotinic acetylcholine receptors (nAChRs) in the primary somatosensory (S1) and motor (M1) cortices of rats after electrical
Publikováno v:
TURKISH JOURNAL OF BIOLOGY. 43:77-88
G protein-coupled receptors (GPCRs) are 7-transmembrane proteins that transduce various extracellular signals into intracellular pathways. They are the major target of neuropeptides, which regulate the development, feeding behavior, mating behavior,
Autor:
Necla Birgül Iyison, İzzet Akiva
Publikováno v:
Turkish Journal of Biology
Volume: 42, Issue: 6 463-470
Volume: 42, Issue: 6 463-470
BRI3 (brain protein I3) is one of the Wnt/s-catenin pathway target genes as indicated by the results of serial analysis of gene expression (SAGE) and microarray analyses performed in our laboratory. The Wnt/s-catenin signaling pathway is an evolution