Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Nechama I Smorodinsky"'
Autor:
Moriya Shmerling, Michael Chalik, Nechama I. Smorodinsky, Alan Meeker, Sujayita Roy, Orit Sagi-Assif, Tsipi Meshel, Artem Danilevsky, Noam Shomron, Shmuel Levinger, Bar Nishry, David Baruchi, Avital Shargorodsky, Ravit Ziv, Avital Sarusi-Portuguez, Maoz Lahav, Marcelo Ehrlich, Bryony Braschi, Elspeth Bruford, Isaac P. Witz, Daniel H. Wreschner
Publikováno v:
ImmunoHorizons. 6:253-272
Syntenic genomic loci on human chromosome 8 and mouse chromosome 15 (mChr15) code for LY6/Ly6 (lymphocyte Ag 6) family proteins. The 23 murine Ly6 family genes include eight genes that are flanked by the murine Ly6e and Ly6l genes and form an Ly6 sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87646f4a2a00f85fec104172b08a2900
https://doi.org/10.4049/immunohorizons.2200018
https://doi.org/10.4049/immunohorizons.2200018
Autor:
Michael Chalick, Oded Jacobi, Edward Pichinuk, Christian Garbar, Armand Bensussan, Alan Meeker, Ravit Ziv, Tania Zehavi, Nechama I Smorodinsky, John Hilkens, Franz-Georg Hanisch, Daniel B Rubinstein, Daniel H Wreschner
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165031 (2016)
Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in hum
Externí odkaz:
https://doaj.org/article/e148be4c47a04d5dbe84a96ede250065
Autor:
Thierry Guillaume, Edward Pichinuk, Gabi Haran, Ravit Ginat-Koton, Armand Bensussan, Daniel B. Rubinstein, Michael Chalik, Daniel H. Wreschner, Alan K. Meeker, Christian Garbar, Ravit Ziv, Itai Benhar, Nechama I. Smorodinsky
Publikováno v:
Cancer Immunology, Immunotherapy. 69:1337-1352
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain, a stable cell-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438462d48cd653cccf9d444c83021ea3
https://doi.org/10.1007/s00262-020-02547-2
https://doi.org/10.1007/s00262-020-02547-2
Autor:
Moriya Shmerling, Michael Chalik, Nechama I. Smorodinsky, Alan Meeker, Sujayita Roy, Orit Sagi-Assif, Tsipi Meshel, Artem Danilevsky, Noam Shomron, Shmuel Levinger, Bar Nishry, David Baruchi, Avital Shargorodsky, Ravit Ziv, Avital Sarusi-Portuguez, Maoz Lahav, Marcelo Ehrlich, Bryony Braschi, Elspeth Bruford, Isaac P. Witz, Daniel H. Wreschner
Syntenic genomic loci on human chromosome 8 (hChr8) and mouse chromosome 15 (mChr15) code for LY6/Ly6 (lymphocyte antigen 6) family proteins. The 23 murine Ly6 family genes include eight genes that are flanked by the murine Ly6e and Ly6l genes and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477f97a0c4064d87ae2f115ee9e8564e
https://doi.org/10.1101/2021.12.16.472998
https://doi.org/10.1101/2021.12.16.472998
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85400 (2014)
The MUC1 tumor associated antigen is highly expressed on a range of tumors. Its broad distribution on primary tumors and metastases renders it an attractive target for immunotherapy. After synthesis MUC1 is cleaved, yielding a large soluble extracell
Externí odkaz:
https://doaj.org/article/29c4e55e053043b88d97fbad586ecb7b
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43459 (2012)
The response to transforming growth factor-β (TGF-β) depends on cellular context. This context is changed in mitosis through selective inhibition of vesicle trafficking, reduction in cell volume and the activation of mitotic kinases. We hypothesize
Externí odkaz:
https://doaj.org/article/91656b5199c94a189ab25783ff4cb54c
Publikováno v:
Cellular and Molecular Life Sciences. 74:2645-2662
The Type-I bone morphogenetic protein receptors (BMPRs), BMPR1A and BMPR1B, present the highest sequence homology among BMPRs, suggestive of functional similitude. However, sequence elements within their extracellular domain, such as signal sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4883b8e568956c05992956256fcf8d
https://doi.org/10.1007/s00018-017-2488-y
https://doi.org/10.1007/s00018-017-2488-y
Autor:
Edward, Pichinuk, Michael, Chalik, Itai, Benhar, Ravit, Ginat-Koton, Ravit, Ziv, Nechama I, Smorodinsky, Gabi, Haran, Christian, Garbar, Armand, Bensussan, Alan, Meeker, Thierry, Guillaume, Daniel B, Rubinstein, Daniel H, Wreschner
Publikováno v:
Cancer immunology, immunotherapy : CII. 69(7)
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain, a stable cell-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::122e605b8c4e92a37fe1df46ab8a51a0
https://pubmed.ncbi.nlm.nih.gov/32219500
https://pubmed.ncbi.nlm.nih.gov/32219500
Autor:
Vasso Apostolopoulos, Lily Stojanovska, Galit Horn, Daniel H. Wreschner, Nechama I. Smorodinsky, Catherine J. Lees, Ian F. C. McKenzie, Geoffrey A. Pietersz
Publikováno v:
PRILOZI. 37:15-25
Immunotherapy using mucin 1 (MUC1) linked to oxidised mannan (MFP) was investigated in an aggressive MUC1+ metastatic tumour, DA3-MUC1 because, unlike many MUC1+ tumour models, DA3-MUC1 is not spontaneously rejected in mice making it an alternative m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c45fc34aebca4cece475155007a69a7
https://doi.org/10.1515/prilozi-2016-0001
https://doi.org/10.1515/prilozi-2016-0001
Autor:
R. Blake Pepinsky, Nathalie di Clemente, Marcelo Ehrlich, Ayelet R. Amsalem, Jean Yves Picard, Nechama I. Smorodinsky, Tal Hirschhorn, Richard L. Cate
Publikováno v:
Journal of Cell Science. 128:1352-1364
The levels and intracellular localization of wild-type transforming growth factor β superfamily (TGFβ-SF) receptors are tightly regulated by endocytic trafficking, shedding and degradation. In contrast, a main regulatory mechanism of mutation-beari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fcc3b87c46abff6745233c624caaa0
https://doi.org/10.1242/jcs.160143
https://doi.org/10.1242/jcs.160143