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Autor:
Theodore M. Tarasow, Bruce E. Eaton, Michael Willis, Fiona M. Jucker, Brian Hicke, Larry Gold, David P. Sebesta, Nebojša Janjié, Dominic Zichi
Publikováno v:
Bioorganicmedicinal chemistry. 5(6)
In vitro selection techniques provide a means of isolating nucleic acid ligands for binding to particular protein targets. Although most aptamers have quite high affinities for their target proteins, it has been shown that post-SELEX modification can