Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nebiyu Abshiru"'
Publikováno v:
Molecules, Vol 26, Iss 14, p 4306 (2021)
Coffee cherry is a rich source of chlorogenic acids (CGAs) and caffeine. In this study we examined the potential antioxidant activity and enzyme inhibitory effects of whole coffee cherries (WCC) and their two extracts on α-amylase, α-glucosidase an
Externí odkaz:
https://doaj.org/article/d1f5f80f440c491dbb1c158a106db0d1
Publikováno v:
Molecules, Vol 26, Iss 9, p 2515 (2021)
Leafy green vegetables contain essential nutrients and are frequently consumed for their perceived health benefits. The purpose of this study was to profile the nutritional and natural bioactive phytochemical compounds extracted from freeze-dried spi
Externí odkaz:
https://doaj.org/article/d6784a068bc54444b7c80b946d68cf4f
Autor:
Jennifer FitzGerald, Sylvie Moureau, Paul Drogaris, Enda O'Connell, Nebiyu Abshiru, Alain Verreault, Pierre Thibault, Muriel Grenon, Noel F Lowndes
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14714 (2011)
BackgroundDot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly defined.Methodology/principal findingsU
Externí odkaz:
https://doaj.org/article/88377b771a5243508fc14e3367b752f9
Data from Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Purpose:Both gain-of-function enhancer of zeste homolog 2 (EZH2) mutations and inactivating histone acetyltransferases mutations, such as CREBBP and EP300, have been implicated in the pathogenesis of germinal center (GC)–derived lymphomas. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c25494f751d349c18a9a0f314e919e
https://doi.org/10.1158/1078-0432.c.6527655
https://doi.org/10.1158/1078-0432.c.6527655
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3a7acc7afb6706436cb46f252d3e0a
https://doi.org/10.1158/1078-0432.22470681
https://doi.org/10.1158/1078-0432.22470681
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:3430-3438
The current work assessed the phytochemical contents of Arabica whole coffee cherry (WCC) and its two commercially available extracts: a minimum 40% chlorogenic acid (CGA; WCCE-1) and 70% caffeine (WCCE-2). Mass spectrometry analyses tentatively iden
Publikováno v:
Food chemistry. 320
Purslane (Portulaca oleracea) is a weed naturally found in driveways, lawns, and fields and edible in many regions of Europe, Asia, the Middle East, Africa, and Australia. The purpose of this study was to compare the nutritional and phytochemical com
Autor:
Emily J. Rendleman, Marc A. Morgan, Maria Gause, Ali Shilatifard, Annika Krueger, Yoh Hei Takahashi, Dale Dorsett, Stacy A. Marshall, Neil L. Kelleher, Lu Wang, Elizabeth T. Bartom, Andrea Piunti, Christie C. Sze, Kaixiang Cao, Edwin R. Smith, Nebiyu Abshiru, Clayton K. Collings, Hans Martin Herz, Ryan Rickels
Publikováno v:
Nature Genetics. 49:1647-1653
Histone H3 lysine 4 monomethylation (H3K4me1) is an evolutionarily conserved feature of enhancer chromatin catalyzed by the COMPASS-like methyltransferase family, which includes Trr in Drosophila melanogaster and MLL3 (encoded by KMT2C) and MLL4 (enc
Autor:
Ryan Rickels, Christie C. Sze, Neil L. Kelleher, Stacy A. Marshall, Andrea Piunti, Kira A. Cozzolino, Marc A. Morgan, Ali Shilatifard, Xiaolin He, Jeffrey N. Savas, Kaixiang Cao, Clayton K. Collings, Nebiyu Abshiru, Hans Martin Herz, Emily J. Rendleman
Publikováno v:
Genes & Development. 31:2003-2014
Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene cis-regulatory sequences such as promoters and enhancers. Here we identify an evolutionarily conserved factor, BRWD2/PHIP, which colocalizes with histone H3K4 methylation geno
Autor:
Neil L. Kelleher, Jeannie M. Camarillo, Nebiyu Abshiru, Paul M. Thomas, Suchitra Swaminathan, Jacek Sikora
Publikováno v:
J Am Soc Mass Spectrom
Histone post-translational modifications (PTMs) are essential for regulating chromatin and maintaining gene expression throughout cell differentiation. Despite the deep level of understanding of immunophenotypic differentiation pathway in hematopoiet