Zobrazeno 1 - 10
of 2 687
pro vyhledávání: '"Neat1"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Nuclear-enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), has been implicated in the colorectal cancer (CRC) progression. However, its upstream mechanism has not been well studied. In the present study, the fu
Externí odkaz:
https://doaj.org/article/c4b267643af3463b8aff9de76e2af49d
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 8, Pp 722-731 (2024)
Abstract Disruption of the alveolar barrier can trigger acute lung injury. This study elucidated the association of methyltransferase‐like 3 (METTL3) with Streptococcus pneumoniae (SP)‐induced apoptosis and inflammatory injury of alveolar epithel
Externí odkaz:
https://doaj.org/article/73e1fe30cc034a6bac5c8e1cbd24445d
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract The lncRNA NEAT1 has been shown to promote the progression of several cancers, containing laryngeal squamous cell carcinoma (LSCC). However, the precise mechanism by which it promotes LSCC progression remains unclear. In this study, we verif
Externí odkaz:
https://doaj.org/article/9bb1a2667d494bb68d2fd62e11ba4153
Autor:
Feng Long, Xue Li, Jingyu Pan, Hailin Ye, Cuixia Di, Yong Huang, Jiawei Li, Xuan Zhou, Huiyi Yi, Qiaozhen Huang, Jing Si
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Chemotherapy is currently one of the most effective methods in clinical cancer treatment. However, chemotherapy resistance is an important reason for poor chemotherapy efficacy and prognosis, which has become an urgent problem to be solved i
Externí odkaz:
https://doaj.org/article/3d27b803bfab40ad8cbed2b7dfce1eb5
Autor:
Shipeng Li, Xia Wang, Xiaozhen Zhao, Jianghong Deng, Weiying Kuang, Junmei Zhang, Xiaohua Tan, Chao Li, Caifeng Li
Publikováno v:
Pediatric Investigation, Vol 8, Iss 2, Pp 101-107 (2024)
ABSTRACT Importance Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease with complex clinical manifestations and prolonged course. The early diagnosis and condition monitoring of SLE are crucial to disease prognosis. Objective T
Externí odkaz:
https://doaj.org/article/3fe8449ff3a244beb55d6f635378f885
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-18 (2024)
Abstract Background Enhancing angiogenesis may be an effective strategy to promote functional recovery after ischemic stroke. Inflammation regulates angiogenesis. Microglia are crucial cells that initiate inflammatory responses after various brain in
Externí odkaz:
https://doaj.org/article/8118997b14784324bab008a848a08c8f
Autor:
Jiayao Wang, Jiehao Zhang, Hao Liu, Lingnan Meng, Xianchun Gao, Yihan Zhao, Chen Wang, Xiaoliang Gao, Ahui Fan, Tianyu Cao, Daiming Fan, Xiaodi Zhao, Yuanyuan Lu
Publikováno v:
Cancer Communications, Vol 44, Iss 4, Pp 469-490 (2024)
Abstract Background Chemoresistance is a major cause of treatment failure in gastric cancer (GC). Heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) is an N6‐methyladenosine (m6A)‐binding protein involved in a variety of cancers. However, w
Externí odkaz:
https://doaj.org/article/eb8215ba60954ea38b26a561ed35a0e8
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Background Sepsis is a systemic inflammatory response which is frequently associated with acute lung injury (ALI). Activating transcription factor 3 (ATF3) promotes M2 polarization, however, the biological effects of ATF3 on macrophage polar
Externí odkaz:
https://doaj.org/article/908ccba57656455b99ec41787a68a750
Autor:
Romane Milcamps, Thomas Michiels
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
ABSTRACTParaspeckles are non-membranous subnuclear bodies, formed through the interaction between the architectural long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) and specific RNA-binding proteins, including the three
Externí odkaz:
https://doaj.org/article/31473c60f64347b8881807a8d7d8339f
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTLong noncoding RNAs (lncRNAs) regulate the progression of type 2 diabetes mellitus complicated with obstructive sleep apnoea (T2DM-OSA). However, the role of the lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) in T2DM-OSA remains unk
Externí odkaz:
https://doaj.org/article/3be3e49b46c44cf2ad4b11abc4e551a6