Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Neale Lopez-Blanco"'
Autor:
Jonathan Nguyen, Jamie K Teer, Liang Wang, Anders Berglund, Fengshen Kuo, Jad Chahoud, Jasreman Dhillon, Youngchul Kim, Ali Hajiran, James J Mulé, Andrew Chang, Nicholas H Chakiryan, Gregory J Kimmel, Carlos Moran-Segura, Daryoush Saeed-Vafa, Esther N Katende, Neale Lopez-Blanco, Phillip Rappold, Philippe E Spiess, Michelle Fournier, Daniel Jeong, Abraham Ari Hakimi, Philipp M Altrock, Brandon J Manley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Introduction In clear cell renal cell carcinoma (ccRCC), tumor-associated macrophage (TAM) induction of CD8+T cells into a terminally exhausted state has been implicated as a major mechanism of immunotherapy resistance, but a deeper biological unders
Externí odkaz:
https://doaj.org/article/2881fd9f660e47b2a1d040258d55687f
Autor:
Nicholas H Chakiryan, Gregory J Kimmel, Youngchul Kim, Ali Hajiran, Ahmet M Aydin, Logan Zemp, Esther Katende, Jonathan Nguyen, Neale Lopez-Blanco, Jad Chahoud, Philippe E Spiess, Michelle Fournier, Jasreman Dhillon, Liang Wang, Carlos Moran-Segura, Asmaa El-Kenawi, James Mulé, Philipp M Altrock, Brandon J Manley
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0245415 (2021)
Immune infiltration is typically quantified using cellular density, not accounting for cellular clustering. Tumor-associated macrophages (TAM) activate oncogenic signaling through paracrine interactions with tumor cells, which may be better reflected
Externí odkaz:
https://doaj.org/article/805e9012c35c46a7a9bcfa1b146ddd89
Autor:
ThuLe Trinh, William A. Adams, Alexandra Calescibetta, Nhan Tu, Robert Dalton, Tina So, Max Wei, Grace Ward, Elena Kostenko, Sean Christiansen, Ling Cen, Amy McLemore, Kayla Reed, Junmin Whitting, Danielle Gilvary, Neale Lopez Blanco, Carlos Moran Segura, Jonathan Nguyen, Wendy Kandell, Xianghong Chen, Pingyan Cheng, Gabriela M. Wright, W. Douglas Cress, Jinghong Liu, Kenneth L. Wright, Sheng Wei, Erika A. Eksioglu
Publikováno v:
iScience
Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells (CAR-Ts). However, despite success in blood malignancies, CAR-T therapies in solid tumors h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2408b53e4f1b036c221c434f2c62c682
https://europepmc.org/articles/PMC10105289/
https://europepmc.org/articles/PMC10105289/
Autor:
Nicholas H Chakiryan, Youngchul Kim, Anders Berglund, Andrew Chang, Gregory J Kimmel, Ali Hajiran, Jonathan Nguyen, Carlos Moran-Segura, Daryoush Saeed-Vafa, Esther N Katende, Neale Lopez-Blanco, Jad Chahoud, Phillip Rappold, Philippe E Spiess, Michelle Fournier, Daniel Jeong, Liang Wang, Jamie K Teer, Jasreman Dhillon, Fengshen Kuo, Abraham Ari Hakimi, Philipp M Altrock, James J Mulé, Brandon J Manley
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006195
IntroductionIn clear cell renal cell carcinoma (ccRCC), tumor-associated macrophage (TAM) induction of CD8+T cells into a terminally exhausted state has been implicated as a major mechanism of immunotherapy resistance, but a deeper biological underst
Autor:
Andrew Chang, Phillip Spiess, Brandon J. Manley, Daniel Jeong, Jad Chahoud, Phillip Altrock, Jamie K. Teer, James J. Mulé, Anders Berglund, Daryoush Saeed-Vafa, Jonathan Nguyen, Carlos Moran, Phillip M Rappold, Esther Katende, A. Ari Hakimi, Gregory J. Kimmel, Michelle Fournier, Nicholas H. Chakiryan, Neale Lopez-Blanco, Liang Wang, Jasreman Dhillon, Dongliang Du, Young-Chul Kim, Ali Hajiran
We performed multiplex immunofluorescence (mIF) using an array of myeloid and lymphoid markers on primary tumor samples from 122 patients with RCC. Regions of interest (ROIs) were selected from three distinct tumor zones: the tumor-core, stroma, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376aae6a0e66cd6a255403394b8cc843
https://doi.org/10.21203/rs.3.rs-847697/v1
https://doi.org/10.21203/rs.3.rs-847697/v1
Autor:
James J. Mulé, Esther Katende, Michelle Fournier, Jad Chahoud, Dongliang Du, Jamie K. Teer, Young-Chul Kim, Neale Lopez-Blanco, Anders Berglund, Chia-Ho Cheng, Jasreman Dhillon, Ahmet M. Aydin, Logan Zemp, Philippe E. Spiess, Liang Wang, Carlos Moran-Segura, Wenyi Fan, Jonathan Nguyen, Sean J. Yoder, Brandon J. Manley, Nicholas H. Chakiryan, Ali Hajiran
Publikováno v:
European urology focus. 8(3)
Background Clear cell renal cell carcinoma (ccRCC) tumors have low frequencies of genetic alterations compared with other malignancies, but very high levels of immune cell infiltration and favorable response rates to immunotherapy. Currently, the int
Autor:
Asmaa El-Kenawi, Gregory J. Kimmel, Carlos Moran-Segura, Jasreman Dhillon, Jad Chahoud, James J. Mule, Logan Zemp, Philippe E. Spiess, Neale Lopez-Blanco, Philipp M. Altrock, Esther Katende, Jonathan Nguyen, Michelle Fournier, Liang Wang, Brandon J. Manley, Ahmet M. Aydin, Nicholas H. Chakiryan, Ali Hajiran, Youngchul Kim
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0245415 (2021)
PLoS ONE
PLoS ONE
Immune infiltration is typically quantified using cellular density, not accounting for cellular clustering. Tumor-associated macrophages (TAM) activate oncogenic signaling through paracrine interactions with tumor cells, which may be better reflected