Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Neal Satterly"'
Autor:
Samuel E Ward, Hyun Seok Kim, Kakajan Komurov, Saurabh Mendiratta, Pei-Ling Tsai, Mirco Schmolke, Neal Satterly, Balaji Manicassamy, Christian V Forst, Michael G Roth, Adolfo García-Sastre, Katarzyna M Blazewska, Charles E McKenna, Beatriz M Fontoura, Michael A White
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e39284 (2012)
Influenza A virus infects 5-20% of the population annually, resulting in ~35,000 deaths and significant morbidity. Current treatments include vaccines and drugs that target viral proteins. However, both of these approaches have limitations, as vaccin
Externí odkaz:
https://doaj.org/article/c5ff6c95095346579020db8ad8961ee7
Publikováno v:
Molecular Biology of the Cell
Unexpected redundancy in the nuclear import pathways used by the essential mRNA export factor NXF1 increases progressively from fungi to nematodes and insects to chordates, potentially paralleling the increasing complexity in mRNA export regulation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c9d795edef983016d5b5ca62b48a95
https://doi.org/10.1091/mbc.e11-03-0222
https://doi.org/10.1091/mbc.e11-03-0222
Autor:
Pei Ling Tsai, Paula A. Faria, Neal Satterly, Agata Levay, David E. Levy, Yaming Wang, Daniel R. Nussenzveig, Beatriz M. A. Fontoura, Jan M. van Deursen
Publikováno v:
Proceedings of the National Academy of Sciences. 104:1853-1858
The NS1 protein of influenza A virus is a major virulence factor that is essential for pathogenesis. NS1 functions to impair innate and adaptive immunity by inhibiting host signal transduction and gene expression, but its mechanisms of action remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92e14cfa0181620ad5fc2716b42c232
https://doi.org/10.1073/pnas.0610977104
https://doi.org/10.1073/pnas.0610977104
Autor:
Adolfo García-Sastre, Shuguang Wei, Michael G. Roth, James Brugarolas, Gijs A. Versteeg, Mirco Schmolke, Michael A. White, Doug E. Frantz, Noelle S. Williams, Miguel A. Mata, Beatriz M. A. Fontoura, Neal Satterly, Samuel Peña-Llopis, Christian V. Forst
Publikováno v:
Nature Chemical Biology, Vol. 7, No 10 (2011) pp. 712-719
A chemical genetics approach was taken to identify inhibitors of NS1, a major influenza A virus virulence factor that inhibits host gene expression. A high-throughput screen of 200,000 synthetic compounds identified small molecules that reversed NS1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d7107c92edc2bb3182345946c9cb6b
https://archive-ouverte.unige.ch/unige:75396
https://archive-ouverte.unige.ch/unige:75396
Autor:
Beatriz M. A. Fontoura, Charles E. McKenna, Mirco Schmolke, Kakajan Komurov, Neal Satterly, Hyun Seok Kim, Michael A. White, Pei Ling Tsai, Samuel E. Ward, Katarzyna M. Błażewska, Saurabh Mendiratta, Christian V. Forst, Balaji Manicassamy, Adolfo García-Sastre, Michael G. Roth
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e39284 (2012)
PLOS ONE, Vol. 7, No 8 (2012) P. e39284
PLoS ONE
PLOS ONE, Vol. 7, No 8 (2012) P. e39284
PLoS ONE
Influenza A virus infects 5-20% of the population annually, resulting in ~35,000 deaths and significant morbidity. Current treatments include vaccines and drugs that target viral proteins. However, both of these approaches have limitations, as vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0681fe33010482c34622cda95a09f8
https://doi.org/10.1371/journal.pone.0039284
https://doi.org/10.1371/journal.pone.0039284