Zobrazeno 1 - 10
of 630
pro vyhledávání: '"Neal R Swerdlow"'
Autor:
James F. Cavanagh, David Gregg, Gregory A. Light, Sarah L. Olguin, Richard F. Sharp, Andrew W. Bismark, Savita G. Bhakta, Neal R. Swerdlow, Jonathan L. Brigman, Jared W. Young
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract There has been a fundamental failure to translate preclinically supported research into clinically efficacious treatments for psychiatric disorders. One of the greatest impediments toward improving this species gap has been the difficulty of
Externí odkaz:
https://doaj.org/article/bb1b45e7bda047b0956a1049197f4bec
Autor:
Peter E. Clayson, Yash B. Joshi, Michael L. Thomas, Joyce Sprock, John Nungaray, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 6, Iss , Pp 100046- (2022)
Patients with schizophrenia have impairments in early auditory system functioning that relate to clinical, cognitive, and psychosocial functioning. Some neurophysiological biomarkers of auditory information processing are sensitive to and predictive
Externí odkaz:
https://doaj.org/article/de04e0159dc04e088e523d1d3a6b521b
Autor:
Juan L. Molina, Michael L. Thomas, Yash B. Joshi, William C. Hochberger, Daisuke Koshiyama, John A. Nungaray, Lauren Cardoso, Joyce Sprock, David L. Braff, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Cognitive impairments are pervasive and disabling features of schizophrenia. Targeted cognitive training (TCT) is a “bottom-up” cognitive remediation intervention with efficacy for neurocognitive outcomes in schizophrenia, yet individual
Externí odkaz:
https://doaj.org/article/2c39f8ad4f0a4638af9528bc001829f8
Correction to: Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms
Autor:
James F. Cavanagh, David Gregg, Gregory A. Light, Sarah L. Olguin, Richard F. Sharp, Andrew W. Bismark, Savita G. Bhakta, Neal R. Swerdlow, Jonathan L. Brigman, Jared W. Young
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c0908ea1423340ad8c0948754a4dccc6
Autor:
Gregory A. Light, Yash B. Joshi, Juan L. Molina, Savita G. Bhakta, John A. Nungaray, Lauren Cardoso, Juliana E. Kotz, Michael L. Thomas, Neal R. Swerdlow
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 2, Iss , Pp 100012- (2020)
Chronic psychotic disorders, including schizophrenia (SZ), are highly heterogeneous at many levels of analysis, from genetics to clinical presentation and treatment sensitivity. This heterogeneity reflects both a divergence of shared biological pathw
Externí odkaz:
https://doaj.org/article/a65e737d3cb24ee881e64baf6d9fefe4
Autor:
Junghee Lee, Michael F Green, Keith H Nuechterlein, Neal R Swerdlow, Tiffany A Greenwood, Gerhard S Hellemann, Laura C Lazzeroni, Gregory A Light, Allen D Radant, Larry J Seidman, Larry J Siever, Jeremy M Silverman, Joyce Sprock, William S Stone, Catherine A Sugar, Debby W Tsuang, Ming T Tsuang, Bruce I Turetsky, Ruben C Gur, Raquel E Gur, David L Braff
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232855 (2020)
Recently emerging evidence indicates accelerated age-related changes in the structure and function of the brain in schizophrenia, raising a question about its potential consequences on cognitive function. Using a large sample of schizophrenia patient
Externí odkaz:
https://doaj.org/article/1500c5e4b8c84ada8bd264b39db08317
Autor:
Yash B. Joshi, Juan L. Molina, David L. Braff, Michael F. Green, Ruben C. Gur, Raquel E. Gur, Keith H. Nuechterlein, William S. Stone, Tiffany A. Greenwood, Laura C. Lazzeroni, Allen D. Radant, Jeremy M. Silverman, Joyce Sprock, Catherine A. Sugar, Debby W. Tsuang, Ming T. Tsuang, Bruce I. Turetsky, Neal R. Swerdlow, Gregory A. Light
Publikováno v:
American Journal of Psychiatry.
Autor:
Savita G. Bhakta, James F. Cavanagh, Jo A. Talledo, Juliana E. Kotz, Lindsay Benster, Benjamin Z. Roberts, John A. Nungaray, Jonathan L. Brigman, Gregory A. Light, Neal R. Swerdlow, Jared W. Young
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 47, iss 5
Neuropsychopharmacology
Neuropsychopharmacology
The poor translatability between preclinical and clinical drug trials has limited pro-cognitive therapeutic development. Future pro-cognitive drug trials should use translatable cross-species cognitive tasks with biomarkers (1) relevant to specific c
Autor:
Neal R. Swerdlow, Yash B. Joshi, Joyce Sprock, Jo Talledo, Juan L. Molina, Lisa Delano-Wood, Dylan Iwanaga, Juliana E. Kotz, Steven Huege, Gabriel C. Léger, Gregory A. Light
Publikováno v:
Journal of Alzheimer's disease : JAD. 91(1)
Background: The uncompetitive NMDA antagonist, memantine (MEM), enhances prepulse inhibition of startle (PPI) across species. MEM is used to treat Alzheimer’s disease (AD); conceivably, its acute impact on PPI might be used to predict a patient’s
Autor:
Joyce Sprock, Debby W. Tsuang, Raquel E. Gur, Yash B. Joshi, Catherine A. Sugar, Laura C. Lazzeroni, Allen D. Radant, William S. Stone, Neal R. Swerdlow, Ming T. Tsuang, David L. Braff, Keith H. Nuechterlein, Bruce I. Turetsky, Michael F. Green, Juan L. Molina, Laura R MacDonald, Michael L. Thomas, Ruben C. Gur, Gregory A. Light, Tiffany A. Greenwood, Jeremy M. Silverman, John Nungaray
Publikováno v:
Am J Psychiatry
OBJECTIVE: Many psychotropic medications used to treat schizophrenia have significant anticholinergic properties, which are linked to cognitive impairment and dementia risk in healthy subjects. Clarifying the impact of cognitive impairment attributab