Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Neal P. Smith"'
Autor:
Jennifer D. Helble, Michael J. Walsh, Julie E. McCarthy, Neal P. Smith, Alice J. Tirard, Benjamin Y. Arnold, Alexandra-Chloe Villani, Linden T. Hu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108217- (2023)
Summary: Lyme disease is caused by the bacterial pathogen Borrelia burgdorferi, which can be readily modeled in laboratory mice. In order to understand the cellular and transcriptional changes that occur during B. burgdorferi infection, we conducted
Externí odkaz:
https://doaj.org/article/d6183220150540f2ace8e1063c19b325
Autor:
Brinda Monian, Ang A. Tu, Bert Ruiter, Duncan M. Morgan, Patrick M. Petrossian, Neal P. Smith, Todd M. Gierahn, Julia H. Ginder, Wayne G. Shreffler, J. Christopher Love
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Food allergy affects an estimated 8% of children in the United States. Oral immunotherapy (OIT) is a recently approved treatment, with outcomes ranging from sustained tolerance to food allergens to no apparent benefit. The immunological underpinnings
Externí odkaz:
https://doaj.org/article/550c45b6120e40ebbcf7f532608dce24
Autor:
Neal P. Smith, Bert Ruiter, Yamini V. Virkud, Ang A. Tu, Brinda Monian, James J. Moon, J. Christopher Love, Wayne G. Shreffler
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
Recent advances in high-throughput T cell receptor (TCR) sequencing have allowed for new insights into the human TCR repertoire. However, methods for capturing antigen-specific repertoires remain an area of development. Here, we describe a potentiall
Externí odkaz:
https://doaj.org/article/a91b4c054bd94f21abe24f6110dcf764
Autor:
Neal R. Smith, James M. Trauer, Manoj Gambhir, Jack S. Richards, Richard J. Maude, Jonathan M. Keith, Jennifer A. Flegg
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Much of the extensive research regarding transmission of malaria is underpinned by mathematical modelling. Compartmental models, which focus on interactions and transitions between population strata, have been a mainstay of such m
Externí odkaz:
https://doaj.org/article/54cc26a8d8444449bde31d3b467f16fe
Autor:
Jehan Alladina, Neal P. Smith, Tristan Kooistra, Kamil Slowikowski, Isabela J. Kernin, Jacques Deguine, Henry L. Keen, Kasidet Manakongtreecheep, Jessica Tantivit, Rod A. Rahimi, Susan L. Sheng, Nhan D. Nguyen, Alexis M. Haring, Francesca L. Giacona, Lida P. Hariri, Ramnik J. Xavier, Andrew D. Luster, Alexandra-Chloé Villani, Josalyn L. Cho, Benjamin D. Medoff
Publikováno v:
Science Immunology. 8
Asthma is a chronic disease most commonly associated with allergy and type 2 inflammation. However, the mechanisms that link airway inflammation to the structural changes that define asthma are incompletely understood. Using a human model of allergen
Autor:
Kamil Slowikowski, Benjamin Y. Arnold, Leyre Zubiri, Katherine Xu, Bo Li, Dejan Juric, Christopher J. Pinto, Swetha Ramesh, Michael Dougan, Jonathan H. Chen, Tatyana Sharova, Genevieve M. Boland, Karin Pelka, Elaina PuiYee Chan, Linda T. Nieman, Molly Thomas, Jessica Tantivit, Pritha Sen, Hamed Khalili, Alice Tirard, Mazen Nasrallah, Rachel Glasser, Alexandra-Chloé Villani, Neal P. Smith, Vjola Jorgji, Ryan J. Sullivan, Kasidet Manakongtreecheep, Kerry L. Reynolds, Nir Hacohen, Thomas Eisenhaure
Therapeutic blockade of co-inhibitory immune receptors PD-1 and CTLA-4 has revolutionized oncology, but treatments are limited by immune-related adverse events (IRAEs). IRAE Colitis (irColitis) is the most common, severe IRAE affecting up to 25% of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a72e208dc156375234ab358e6b64f874
https://doi.org/10.1101/2021.09.17.460868
https://doi.org/10.1101/2021.09.17.460868
Autor:
Neal P. Smith, J. Christopher Love, Wayne G. Shreffler, Navneet Virk-Hundal, Bert Ruiter, Qian Yuan, Brandon E. Stone, Brinda Monian, Duncan M. Morgan, Ang A. Tu
Publikováno v:
Science Immunology. 6
Eosinophilic esophagitis (EoE) is an allergic disorder characterized by the recruitment of eosinophils to the esophagus, resulting in chronic inflammation. We sought to understand the cellular populations present in tissue biopsies of patients with E
Autor:
Brinda Monian, Wayne G. Shreffler, J. Christopher Love, Neal P. Smith, Todd M. Gierahn, Bert Ruiter, Julia H. Ginder, Patrick M. Petrossian, Duncan M. Morgan, Ang A. Tu
Food allergy affects an estimated 8% of children in the US, with increasing severity and global prevalence1. Oral immunotherapy (OIT) is a recently approved treatment with outcomes ranging from sustained tolerance to food allergen to no apparent bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2024d4c40620207bbb89027e133e6263
https://doi.org/10.1101/2021.07.29.21261049
https://doi.org/10.1101/2021.07.29.21261049
Autor:
J. Christopher Love, Neal P. Smith, Ang A. Tu, Wayne G. Shreffler, Bert Ruiter, James J. Moon, Brinda Monian, Yamini V. Virkud
Publikováno v:
JCI Insight
Recent advances in high-throughput T cell receptor (TCR) sequencing have allowed for new insights into the human TCR repertoire. However, methods for capturing antigen-specific repertoires remain an area of development. Here, we describe a potentiall
Autor:
Kenneth K. Yu, Neal P. Smith, Sernah V. Essien, Jessica E. Teague, Pablo Vieyra-Garcia, Ahmed Gehad, Qian Zhan, Jack D. Crouch, Nega Gerard, Cecilia Larocca, Peter Wolf, Nicole R. LeBoeuf, Marianne Tawa, Thomas S. Kupper, Alexandra-Chloé Villani, Rachael A. Clark
Publikováno v:
Journal of Investigative Dermatology. 142:2285-2288.e2