Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Neal M Poulin"'
Autor:
Aimée N Laporte, Jared J Barrott, Ren Jie Yao, Neal M Poulin, Bertha A Brodin, Kevin B Jones, T Michael Underhill, Torsten O Nielsen
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169407 (2017)
Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting its driving SS18-SSX fusion oncoprotein are currently available. Patients remain at high risk for early and late metastasis. A high-thr
Externí odkaz:
https://doaj.org/article/e797ab58c4db4ec2a72c9d3cc3c07f48
Autor:
Torsten O. Nielsen, T. Michael Underhill, Kevin B. Jones, Ryan Vander Werff, Alireza Lorzadeh, Xiu Qing Wang, Jared J. Barrott, Neal M. Poulin, Aimée N. Laporte
Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting the causative SS18-SSX fusion oncoprotein are currently available. Histone deacetylase (HDAC) inhibition has been shown in previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c10f6cdb068b2c8767e065bacb13cb
https://doi.org/10.1158/1535-7163.c.6538087.v1
https://doi.org/10.1158/1535-7163.c.6538087.v1
Autor:
Torsten O. Nielsen, T. Michael Underhill, Kevin B. Jones, Ryan Vander Werff, Alireza Lorzadeh, Xiu Qing Wang, Jared J. Barrott, Neal M. Poulin, Aimée N. Laporte
Supplementary Figure S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317a9992f95c02c375a6d6011253bc91
https://doi.org/10.1158/1535-7163.22505494
https://doi.org/10.1158/1535-7163.22505494
Autor:
Lennert S. Ploeger, André Huisman, Jurryt van der Gugten, Dionne M. van der Giezen, Jeroen A. M. Beliën, Abdelhadi Y. Abbaker, Hub F. J. Dullens, William Grizzle, Neal M. Poulin, Gerrit A. Meijer, Paul J. van Diest
Publikováno v:
Cellular Oncology, Vol 27, Iss 4, Pp 225-230 (2005)
Background: DNA cytometry is a powerful method for measuring genomic instability. Standard approaches that measure DNA content of isolated cells may induce selection bias and do not allow interpretation of genomic instability in the context of the ti
Externí odkaz:
https://doaj.org/article/35479b27347e4e54aa3fbad40ee3dc30
Autor:
Aimée N. Laporte, Kevin B. Jones, Neal M. Poulin, Jared J. Barrott, Alireza Lorzadeh, Torsten O. Nielsen, Ryan Vander Werff, T. Michael Underhill, Xiu Qing Wang
Publikováno v:
Molecular Cancer Therapeutics. 16:2656-2667
Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting the causative SS18-SSX fusion oncoprotein are currently available. Histone deacetylase (HDAC) inhibition has been shown in previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb8345d708d41043671c249cbbd8f2b
https://doi.org/10.1158/1535-7163.mct-17-0397
https://doi.org/10.1158/1535-7163.mct-17-0397
Publikováno v:
Sarcoma, Vol 2009 (2009)
Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models. We
Externí odkaz:
https://doaj.org/article/e42f70ba67fe4c439b551c12bc33b063
Autor:
T. Michael Underhill, Bertha Brodin, Aimeâe N. Laporte, Jared J. Barrott, Torsten O. Nielsen, Ren Jie Yao, Neal M. Poulin, Kevin B. Jones
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169407 (2017)
PLoS ONE
PLoS ONE
Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting its driving SS18-SSX fusion oncoprotein are currently available. Patients remain at high risk for early and late metastasis. A high-thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baee2e34cf80d4600ea8fdc452a79ae7
http://europepmc.org/articles/PMC5215898?pdf=render
http://europepmc.org/articles/PMC5215898?pdf=render
Autor:
Neal M. Poulin, Michelle Moska, Jared J. Barrott, Gregg B. Morin, Aimée N. Laporte, Xiu Qing Wang, Martin Hirst, Alireza Lorzadeh, Torsten O. Nielsen, Kevin B. Jones, Ryan Vander Werff, T. Michael Underhill, Christopher S. Hughes
Publikováno v:
Clinical Cancer Research. 24:A13-A13
Introduction: Conventional cytotoxic therapies for synovial sarcoma provide limited benefit, and no drugs specifically targeting its driving SS18-SSX fusion oncoprotein are currently available. HDAC inhibition has been shown in previous studies to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85b9253f1322cddfac0cb177aacae7c
https://doi.org/10.1158/1557-3265.sarcomas17-a13
https://doi.org/10.1158/1557-3265.sarcomas17-a13
Autor:
Matt van de Rijn, Neal M. Poulin, Hongwei Cheng, Torsten O. Nielsen, Erika Mehl, Shuzhen Liu, Jim Dodge
Publikováno v:
Human Pathology. 40:1244-1251
Myxoid liposarcoma displays variably aggressive behavior and responds poorly to available systemic therapies. Expression profiling followed by tissue microarray validation linked to patient outcome is a powerful approach for validating biological mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bda6649017404dcbefb64b0f0bdf8c3
https://doi.org/10.1016/j.humpath.2009.01.011
https://doi.org/10.1016/j.humpath.2009.01.011
Autor:
Inigo Espinosa, Subbaya Subramanian, Torsten O. Nielsen, Cheng-Han Lee, Shirley Zhu, Robert J. Marinelli, Matt van de Rijn, Johannes L. Peterse, C. Blake Gilks, Neal M. Poulin, Robert B. West, Kelli Montgomery, Suzan Vrijaldenhoven
Publikováno v:
Clinical Cancer Research. 14:1423-1430
Purpose: Macrophages are migratory cells that are frequently recruited to the site of tumors. Their presence is associated with poor clinical outcome in a variety of epithelial malignancies. The aim of this study is to examine the prognostic signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a696cc5130da048b71d42436345f5a
https://doi.org/10.1158/1078-0432.ccr-07-1712
https://doi.org/10.1158/1078-0432.ccr-07-1712