Výsledky vyhledávání - "Neal J. Dawson"

Akademický článek

Autor: Kyle K. Biggar, Neal J. Dawson, Kenneth B. Storey

Publikováno v: BioTechniques, Vol 62, Iss 1, p xiii (2017)

Protocol Summary Here we present a new protocol to analyze protein unfolding kinetics using a quantified real-time thermocycler. This technique enables the analysis of a wide range of denaturants (and their interactions with temperature change) on pr

Externí odkaz: https://doaj.org/article/deb20695c62a438982f1036d13333283

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Akademický článek

Real-time protein unfolding: a method for determining the kinetics of native protein denaturation using a quantitative real-time thermocycler

Autor: Kyle K. Biggar, Neal J. Dawson, Kenneth B. Storey

Publikováno v: BioTechniques, Vol 53, Iss 4, Pp 231-238 (2012)

Protein stability can be monitored by many different techniques. However, these protocols are often lengthy, consume large amounts of protein, and require expensive and specialized instruments. Here we present a new protocol to analyze protein unfold

Externí odkaz: https://doaj.org/article/074150a2ec4a4e409003a4626e73bd6a

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Akademický článek

Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl

Autor: Neal J Dawson, Luis Alza, Gabriele Nandal, Graham R Scott, Kevin G McCracken

Publikováno v: eLife, Vol 9 (2020)

High-altitude environments require that animals meet the metabolic O2 demands for locomotion and thermogenesis in O2-thin air, but the degree to which convergent metabolic changes have arisen across independent high-altitude lineages or the speed at

Externí odkaz: https://doaj.org/article/794e9188d0404fd48dfdbf6c1c989f20

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Climate change‐induced deprivation of dietary essential fatty acids can reduce growth and mitochondrial efficiency of wild juvenile salmon

Autor: Martin J. Kainz, Amélie Crespel, Libor Závorka, Magdalene Papatheodoulou, Shaun S. Killen, Neal J. Dawson

Publikováno v: Functional Ecology. 35:1960-1971

1. Omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) are essential micronutrients for optimal functioning of cellular metabolism and for somatic growth of all vertebrates including fishes. In addition, n-3 LC-PUFA could also play a key rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5db40061b5aa0b4ddbe0ecc4e2436ba1
https://doi.org/10.1111/1365-2435.13860

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Adaptive increases in respiratory capacity and O 2 affinity of subsarcolemmal mitochondria from skeletal muscle of high‐altitude deer mice

Autor: Neal J. Dawson, Graham R. Scott

Publikováno v: The FASEB Journal. 36

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a18540bfc4dea7dd3250869eee1245ad
https://doi.org/10.1096/fj.202200219r

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Avian red blood cell mitochondria produce more heat in winter than in autumn

Autor: Neil B. Metcalfe, Jennifer L. Page, Dominic J. McCafferty, Andreas Nord, Neal J. Dawson, Anna Huxtable

Publikováno v: The FASEB Journal. 35

Endotherms in cold regions improve heat-producing capacity when preparing for winter. We know comparatively little about how this change is fueled by seasonal adaptation in cellular respiration. Thus, we studied the changes of mitochondrial function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641e198fb860986ca81843e80790cc5d
https://doi.org/10.1096/fj.202100107r

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Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model

Autor: Gregory G. Vandenberg, Alison Head, Angela L. Scott, Graham R. Scott, Neal J. Dawson

Publikováno v: Neurochemistry international. 146

Astrocytes, glial cells within the brain, work to protect neurons during high levels of activity by maintaining oxidative homeostasis via regulation of energy supply and antioxidant systems. In recent years, mitochondrial dysfunction has been highlig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360b9c2f8d034f084b13e74303f1ec2f
https://pubmed.ncbi.nlm.nih.gov/33785420

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Akademický článek

Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure.

Autor: Neal J Dawson, Kyle K Biggar, Kenneth B Storey

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68830 (2013)

One of the most adaptive facultative anaerobes among vertebrates is the freshwater turtle, Trachemys scripta elegans. Upon a decrease in oxygen supply and oxidative phosphorylation, these turtles are able to reduce their metabolic rate and recruit an

Externí odkaz: https://doaj.org/article/a52e52cf2fcf498ea4930dbd4cd24464

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