Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Neal Goodwin"'
Autor:
Alex Q. Lee, Masami Ijiri, Ryan Rodriguez, Regina Gandour-Edwards, Joyce Lee, Clifford G. Tepper, Yueju Li, Laurel Beckett, Kit Lam, Neal Goodwin, Noriko Satake
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundRenal medullary carcinoma (RMC) is a rare but aggressive tumor often complicated by early lung metastasis with few treatment options and very poor outcomes. There are currently no verified RMC patient-derived xenograft (PDX) mouse models es
Externí odkaz:
https://doaj.org/article/5b60847d3e534d3bab9c801d66a9275f
Autor:
Xing Yi Woo, Anuj Srivastava, Philip C. Mack, Joel H. Graber, Brian J. Sanderson, Michael W. Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A. Tsai, James Keck, Mingshan Cheng, Margaret Bundy, Emily L. Jocoy, Jonathan W. Riess, William Holland, Stephen C. Grubb, James G. Peterson, Grace A. Stafford, Carolyn Paisie, Steven B. Neuhauser, R. Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G. Tepper, Neal Goodwin, Susan D. Airhart, Primo N. Lara, Thomas H. Openshaw, Edison T. Liu, David R. Gandara, Carol J. Bult
Publikováno v:
Cancer Res
Cancer research, vol 82, iss 22
Cancer research, vol 82, iss 22
Patient-derived xenograft (PDX) models are an effective preclinical in vivo platform for testing the efficacy of novel drugs and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Patient-derived xenograft (PDX) models are an effective preclinical in vivo platform for testing the efficacy of novel drugs and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5cefc3df68748c1456699cbfa512e4c
https://doi.org/10.1158/0008-5472.c.6514248.v1
https://doi.org/10.1158/0008-5472.c.6514248.v1
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Supplementary Table from A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b1a58d4d6ddc9eaba431d6c2bee5b6
https://doi.org/10.1158/0008-5472.22432782
https://doi.org/10.1158/0008-5472.22432782
Autor:
Carol J. Bult, David R. Gandara, Edison T. Liu, Thomas H. Openshaw, Primo N. Lara, Susan D. Airhart, Neal Goodwin, Clifford G. Tepper, Margaret Chavaree, Allen K. Simons, Joshy George, R. Krishna Murthy Karuturi, Steven B. Neuhauser, Carolyn Paisie, Grace A. Stafford, James G. Peterson, Stephen C. Grubb, William Holland, Jonathan W. Riess, Emily L. Jocoy, Margaret Bundy, Mingshan Cheng, James Keck, Rebekah A. Tsai, Regina Gandour-Edwards, Sergii Domanskyi, Mandy Chen, Michael W. Lloyd, Brian J. Sanderson, Joel H. Graber, Philip C. Mack, Anuj Srivastava, Xing Yi Woo
Supplementary Figure from A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b25cbe2de39330bf2d95fba69463be
https://doi.org/10.1158/0008-5472.22432803
https://doi.org/10.1158/0008-5472.22432803
Autor:
Xing Yi Woo, Anuj Srivastava, Philip C. Mack, Joel H. Graber, Brian J. Sanderson, Michael W. Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A. Tsai, James Keck, Mingshan Cheng, Margaret Bundy, Emily L. Jocoy, Jonathan W. Riess, William Holland, Stephen C. Grubb, James G. Peterson, Grace A. Stafford, Carolyn Paisie, Steven B. Neuhauser, R. Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G. Tepper, Neal Goodwin, Susan D. Airhart, Primo N. Lara, Thomas H. Openshaw, Edison T. Liu, David R. Gandara, Carol J. Bult
Patient-derived xenograft models (PDXs) are an effective preclinical in vivo platform for testing the efficacy of novel drug and drug combinations for cancer therapeutics. Here we describe a repository of 79 genomically and clinically annotated lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::869bca19f757761d5d2607c942cc728d
https://doi.org/10.1101/2022.03.06.483171
https://doi.org/10.1101/2022.03.06.483171
Autor:
Marina Konopleva, Tamar Uziel, Xiaoli Huang, Weiguo Feng, Xiaoyu Lin, Warren M. Kati, Lloyd T. Lam, Vinitha Mary Kuruvilla, Mai H. Bui, Emily J. Faivre, Tianyu Cai, Jenny Rowe, Daniel H. Albert, Richard J. Bellin, Lu Zhang, Zheng Zha, Sriram S. Shanmugavelandy, Paul Hessler, Michael Boyiadzis, Gaurav Mehta, Antonio Cavazos, Keith F. McDaniel, Joshua P. Plotnik, Terrance J. Magoc, Xin Lu, Debra Ferguson, Yu Shen, Lina Han, Neal Goodwin, Qi Zhang, Kathleen A. Dorritie
Publikováno v:
Molecular cancer therapeutics. 20(10)
Dual bromodomain BET inhibitors that bind with similar affinities to the first and second bromodomains across BRD2, BRD3, BRD4, and BRDT have displayed modest activity as monotherapy in clinical trials. Thrombocytopenia, closely followed by symptoms
Autor:
Matthew H. Brush, Theodore C. Goldstein, Yvonne A. Evrard, Nathalie Conte, Melissa A. Haendel, Kevin C K Lloyd, Annette T. Byrne, Peter J. Houghton, Carlos Caldas, Amanda L. Christie, Frédéric Amant, Alana L. Welm, Stefan M. Pfister, Mark A. Murakami, Jos Jonkers, Patrick Dunn, Tin Oo Khor, Danielle Greenawalt, Jonathan R. Dry, David M. Weinstock, Sebastian Brabetz, Oscar M. Rueda, Zhiping Gu, Giorgio Inghirami, Dominic Clark, Olivier Duchamp, James M. Olson, Emilie Vinolo, Neal Goodwin, Kristopher K. Frese, Robert J. Wechsler-Reya, Terrence F. Meehan, Daniel S. Peeper, Marcel Kool, Enzo Medico, Jeremy Mason, Stephane Ferretti, Carol J. Bult, Atul J. Butte, S. John Weroha, Els Hermans, Kristel Kemper, Alejandra Bruna, Heidi Dowst, Je Kyung Seong, James H. Doroshow, Livio Trusolino, Michael T. Lewis, Jeffrey Wiser, Dale A. Begley, Steven B. Neuhauser, Helen Parkinson, Debra M. Krupke, Andrea Bertotti
Publikováno v:
Cancer research, 77(21), e62-e66. American Association for Cancer Research Inc.
Cancer research, vol 77, iss 21
Cancer research, vol 77, iss 21
Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research platform to study tumor evolution, mechanisms of drug response and resistance, and tailoring chemotherapeutic approaches for individual patients. The la
Autor:
Narendra Bharathy, Douglas S. Hawkins, Arya Ashok, Martin Goros, Atiya Mansoor, Erin R. Rudzinski, Ranadip Pal, Christopher J. Noakes, James G. Keck, Matthew N. Svalina, Johannes E. A. Wolff, Maria Cecilia Mancini, Joel E. Michalek, Charles Keller, Jinu Abraham, Zia Bajwa, Neal Goodwin, Eric Wang, Teagan P. Settelmeyer, Darnell Bushby, Christopher R. Vakoc, Angela M Davies, Theodore J. Perkins, Noah E. Berlow, Peter Ordentlich, Brian Hernandez, Jody E. Hooper
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-10 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-10 (2019)
Background Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric cancer population. Survival among metastatic RMS patients has remained dismal yet unimproved for years. We previously identified the class I-specific histone de
Autor:
Arya Ashok, Teagan P. Settelmeyer, Christopher J. Noakes, Johannes E. A. Wolff, Eric Wang, Darnell Bushby, Linping Xu, Frederic G. Barr, Ranadip Pal, Jody E. Hooper, Jennifer C. Liddle, Yoshihiro Ishikawa, Bishwanath Chatterjee, Narendra Bharathy, Joel E. Michalek, Jinu Abraham, Maria Cecilia Mancini, Neal Goodwin, James G. Keck, Martin Goros, Atiya Mansoor, Charles Keller, Nicole M. Anders, Zia Bajwa, Keith D. Zientek, Peter Ordentlich, Matthew N. Svalina, Douglas S. Hawkins, Alexandria P. Harrold, Christopher R. Vakoc, Angela M Davies, Erin R. Rudzinski, Brian Hernandez, Michelle A. Rudek, Theodore J. Perkins, Benjamin A. Garcia, Noah E. Berlow, Hans Peter Bächinger
Publikováno v:
Science Signaling. 11
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood with an unmet clinical need for decades. A single oncogenic fusion gene is associated with treatment resistance and a 40 to 45% decrease in overall survival. We previously sho