Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Neal F. Gordon"'
Publikováno v:
Processes
Volume 9
Issue 8
Processes, Vol 9, Iss 1430, p 1430 (2021)
Volume 9
Issue 8
Processes, Vol 9, Iss 1430, p 1430 (2021)
The COVID-19 pandemic has motivated the rapid development of numerous vaccines that have proven effective against SARS-CoV-2. Several of these successful vaccines are based on the adenoviral vector platform. The mass manufacturing of these vaccines p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415d67c264e7afc249054630e8d7e20d
https://doi.org/10.3390/pr9081430
https://doi.org/10.3390/pr9081430
Autor:
Neal F. Gordon, Jeffrey A. Radding, Amy B. Hall, Cheryl Murphy, Nathan C. Tedford, James R. Graham
Publikováno v:
PROTEOMICS. 9:1469-1487
Protein phosphorylation is a primary form of information transfer in cell signaling pathways and plays a crucial role in regulating biological responses. Aberrant phosphorylation has been implicated in a number of diseases, and kinases and phosphatas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466825bfd58138274bc0e9a0b9e7fd55
https://doi.org/10.1002/pmic.200800468
https://doi.org/10.1002/pmic.200800468
Autor:
James R. Graham, Amy B. Hall, Cheryl Murphy, Christine Rauh-Adelmann, Timothy K. Nadler, Lucy G. Yen, Neal F. Gordon, Jeffrey A. Radding
Publikováno v:
SLAS Discovery. 13:626-637
Cellular homeostasis and responses to stimuli are mediated by complex signaling network events dominated by changes in protein phosphorylation states. Understanding information flow in the network is essential for correlating signaling changes to cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cdb1a8fe8fd6e15969ef26049841fd
https://doi.org/10.1177/1087057108319978
https://doi.org/10.1177/1087057108319978
Autor:
Christine Rauh-Adelmann, Lucy G. Yen, John M. Moskow, Cheryl E. Murphy, Jeffrey A. Radding, Neal F. Gordon, Jeffrey I. Boucher, James R. Graham, Timothy K. Nadler
Publikováno v:
Analytical Biochemistry. 375:255-264
Aberrant epidermal growth factor receptor (EGFR, ErbB1) signaling is implicated in cell transformation, motility, and invasion in a variety of cell types, and EGFR is the target of several anticancer drugs. However, the kinetics of EGFR signaling and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13334e0bb4f87fa7269cfc944c49c2d7
https://doi.org/10.1016/j.ab.2007.12.038
https://doi.org/10.1016/j.ab.2007.12.038
Autor:
Brian L Clark, Neal F Gordon
Publikováno v:
Methods. 32:63-69
Based on genetic diversity in the population, there is an expectation, born out by decades of experience, that a given drug or treatment will not be equally efficacious for all patients. While this fact cannot be avoided, with ever increasing knowled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957da3ccb336a120b1f97c07f5823dd0
https://doi.org/10.1016/s1046-2023(03)00188-9
https://doi.org/10.1016/s1046-2023(03)00188-9
Publikováno v:
Letters in Peptide Science. 5:285-297
Methods for peptide assembly consist of techniques that allow for construction of complex sequences. The advantage of solid-phase methodologies is automation of the repetitive processes of deprotecting, washing, and coupling protected amino acids (ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e071366f83157b0857f64c9fcc7e20cf
https://doi.org/10.1007/bf02443546
https://doi.org/10.1007/bf02443546
Publikováno v:
Journal of Chromatography A. 807:165-184
Perfusion chromatography is uniquely characterized by the flow of a portion of the column eluent directly through the resin in the packed bed. The benefits of this phenomenon and some of the properties of perfusive resins have been described before,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd21b68ac13c2d7b3818ba46d65b35b
https://doi.org/10.1016/s0021-9673(98)00068-5
https://doi.org/10.1016/s0021-9673(98)00068-5
Publikováno v:
Journal of Chromatography A. 798:73-82
Recovery of recombinant proteins from endogenous, host molecules can be an experimentally intensive and time-consuming task. Often the time to analyze material during development of recovery procedures is the rate-limiting step. Nowadays, modern tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b1eee06e8cde7f043dd2ffe91fd360
https://doi.org/10.1016/s0021-9673(97)01205-3
https://doi.org/10.1016/s0021-9673(97)01205-3
Autor:
Fred E. Regnier, Neal F. Gordon, George Vella, Tim Nadler, Christopher Blackburn, Jonathan Mark
Publikováno v:
Journal of Chromatography A. 743:91-98
A new, rapid, automated method for peptide mapping has been developed that requires less than two hours to complete. This method first (i) reduces the protein with dithiothreitol (DTT) or s-mercaptoethanol at 50°C, (ii) then alkylates it with an alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55aba6c2c6cdf948bed2e40a7bdef72
https://doi.org/10.1016/0021-9673(96)00359-7
https://doi.org/10.1016/0021-9673(96)00359-7
Autor:
R.A Hamilton, Neal F. Gordon, A Schutz, S. D. Putney, P.D Lynch, A.J Hunt, X Cao, Tom Londo, T McCormack, P Dimond, M Percoskie, J.P McGrath
Publikováno v:
Journal of Chromatography A. 708:61-70
A purification process and an on-line process monitoring procedure for a human nerve growth factor (NGF) fusion antibody (NAK) was developed. The NAK protein was produced with a recombinant technique by an adherent Chinese hamster ovary cell line in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3811a9c687c175fa615e125825fbae01
https://doi.org/10.1016/0021-9673(95)00376-x
https://doi.org/10.1016/0021-9673(95)00376-x