Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Neal Dalton"'
Autor:
Renate Griffith, Neal Dalton, Stephen G. Pyne, John B. Bremner, Nicholas Vandegraaff, Christopher P. Gordon, David Ian Rhodes, John Deadman, Paul A. Keller, Jonathan Coates
Publikováno v:
Tetrahedron. 74:1253-1268
As of mid-2017, only one structure of the human immunodeficiency virus (HIV) integrase core domain co-crystallised with an active site inhibitor was reported. In this structure (1QS4), integrase is complexed with a diketo-acid based strand-transfer i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b01d36991a3ccfa2ca92124140f0ba
https://doi.org/10.1016/j.tet.2017.11.052
https://doi.org/10.1016/j.tet.2017.11.052
Autor:
Christopher P. Gordon, Timothy P. Boyle, Stephen G. Pyne, Nicholas Vandegraaf, Neal Dalton, David Ian Rhodes, John B. Bremner, John Deadman, Paul A. Keller, Jonathan Coates
Publikováno v:
Organic & Biomolecular Chemistry. 14:6010-6023
From library screening of synthetic antimicrobial peptides, an O-allyltyrosine-based tripeptide was identified to possess inhibitory activity against HIV-1 integrase (IN) exhibiting an IC50 value of 17.5 μM in a combination 3'-processing and strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25497e7fca3362bb5ba543ed92462cd0
https://doi.org/10.1039/c6ob00950f
https://doi.org/10.1039/c6ob00950f