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Autor:
Renate Griffith, Neal Dalton, Stephen G. Pyne, John B. Bremner, Nicholas Vandegraaff, Christopher P. Gordon, David Ian Rhodes, John Deadman, Paul A. Keller, Jonathan Coates
Publikováno v:
Tetrahedron. 74:1253-1268
As of mid-2017, only one structure of the human immunodeficiency virus (HIV) integrase core domain co-crystallised with an active site inhibitor was reported. In this structure (1QS4), integrase is complexed with a diketo-acid based strand-transfer i
Autor:
Christopher P. Gordon, Timothy P. Boyle, Stephen G. Pyne, Nicholas Vandegraaf, Neal Dalton, David Ian Rhodes, John B. Bremner, John Deadman, Paul A. Keller, Jonathan Coates
Publikováno v:
Organic & Biomolecular Chemistry. 14:6010-6023
From library screening of synthetic antimicrobial peptides, an O-allyltyrosine-based tripeptide was identified to possess inhibitory activity against HIV-1 integrase (IN) exhibiting an IC50 value of 17.5 μM in a combination 3'-processing and strand
Publikováno v:
Social Choice & Welfare. Oct2002, Vol. 19 Issue 4, p885. 16p.
Autor:
Dalton, Neal, Gordon, Christopher P., Boyle, Timothy P., Vandegraaf, Nicholas, Deadman, John, Rhodes, David I., Coates, Jonathan A., Pyne, Stephen G., Keller, Paul A., Bremner, John B.
Publikováno v:
Organic & Biomolecular Chemistry; 7/7/2016, Vol. 14 Issue 25, p6010-6023, 14p
Publikováno v:
Inequalities: Theory of Majorization & Its Applications; 2011, p797-909, 113p
Autor:
Johnson, James R., Brown, Jennifer J.
Publikováno v:
Journal of Infectious Diseases; 1996, Vol. 173 Issue 4, p920-926, 7p
Autor:
Mary M. Dalton, Laura R. Linder
Popular representations of teachers and teaching are easy to take for granted precisely because they are so accessible and pervasive. Our lives are intertextual in the way lived experiences overlap with the stories of others presented to us through m
Autor:
Ken Hughes
Between April and November of 1888, a shadow descended upon the streets of London's East End. Night workers – predominantly prostitutes – were targeted in a brutal series of murders. Of the dozen reported killings, six bore the chilling signature