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MicroRNA-146a deficiency enhances host protection against murine cytomegalovirus.

Autor: Wong P; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Leong JW; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Sohn H; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., Chang L; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Keppel CR; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Neal CC; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Cubitt CC; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Yao T; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Keppel MP; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., Tran J; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Burdi A; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Hwang K; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Fogel LA; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., Schappe T; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Marsala L; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Berrien-Elliott MM; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Wagner JA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Schneider SE; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Sullivan RP; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Pingel JT; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., Cooper MA; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., French AR; Divison of Rheumatology/Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA., Fehniger TA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

Publikováno v: European journal of immunology [Eur J Immunol] 2024 Sep 09, pp. e2451173. Date of Electronic Publication: 2024 Sep 09.

Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant.

Autor: Bednarski JJ; Division of Hematology and Oncology, Department of Pediatrics, and., Zimmerman C; Division of Hematology and Oncology, Department of Pediatrics, and., Berrien-Elliott MM; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Foltz JA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Becker-Hapak M; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Neal CC; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Foster M; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Schappe T; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., McClain E; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Pence PP; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Desai S; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Kersting-Schadek S; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Wong P; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Russler-Germain DA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fisk B; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Lie WR; MilliporeSigma, St. Louis, MO; and., Eisele J; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Hyde S; Division of Hematology and Oncology, Department of Pediatrics, and., Bhatt ST; Division of Hematology and Oncology, Department of Pediatrics, and., Griffith OL; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Griffith M; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Petti AA; Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO., Cashen AF; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fehniger TA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.

Publikováno v: Blood [Blood] 2022 Mar 17; Vol. 139 (11), pp. 1670-1683.

A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells.

Autor: Cubitt CC; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., McClain E; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Becker-Hapak M; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Foltz JA; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Wong P; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Wagner JA; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Neal CC; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Marin ND; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Marsala L; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Foster M; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Schappe T; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Soon-Shiong P; ImmunityBio, Culver City, CA 90232, USA., Lee J; ImmunityBio, Culver City, CA 90232, USA., Berrien-Elliott MM; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA., Fehniger TA; Washington University School of Medicine, 425 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110, USA.

Publikováno v: Molecular therapy oncolytics [Mol Ther Oncolytics] 2022 Feb 15; Vol. 24, pp. 585-596. Date of Electronic Publication: 2022 Feb 15 (Print Publication: 2022).

Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood-Derived NK Cells Facilitates CAR-like Responses Against CD30 ⁺ Malignancies.

Autor: Kerbauy LN; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Departments of Stem Cell Transplantation and Hemotherapy/Cellular Therapy, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.; Human Genome and Stem Cell Research Center, Department of Genetics and Evolutionary Biology, Biosciences Institute, University of São Paulo (USP), Sao Paulo, Brazil., Marin ND; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Kaplan M; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Banerjee PP; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Berrien-Elliott MM; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Becker-Hapak M; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Basar R; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Foster M; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Garcia Melo L; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Neal CC; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., McClain E; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Daher M; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Nunez Cortes AK; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Desai S; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Inng Lim FW; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mendt MC; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Schappe T; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Li L; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shaim H; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shanley M; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ensley EL; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Uprety N; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wong P; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri., Liu E; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ang SO; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cai R; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Nandivada V; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mohanty V; Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Miao Q; Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Shen Y; Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Baran N; Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Fowlkes NW; Department of Veterinary Medicine and Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Chen K; Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas., Muniz-Feliciano L; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Champlin RE; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Nieto YL; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Koch J; Affimed GmbH, Heidelberg, Germany., Treder M; Arjuna Therapeutics, Santiago de Compostela, Spain., Fischer W; Affimed GmbH, Heidelberg, Germany., Okamoto OK; Departments of Stem Cell Transplantation and Hemotherapy/Cellular Therapy, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.; Human Genome and Stem Cell Research Center, Department of Genetics and Evolutionary Biology, Biosciences Institute, University of São Paulo (USP), Sao Paulo, Brazil., Shpall EJ; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Fehniger TA; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri. krezvani@mdanderson.org tfehnige@wustl.edu., Rezvani K; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas. krezvani@mdanderson.org tfehnige@wustl.edu.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Jul 01; Vol. 27 (13), pp. 3744-3756. Date of Electronic Publication: 2021 May 13.