Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Neal A. Yakelis"'
Autor:
Donna Prunkard, Angelina V Gladchuk, Neal A. Yakelis, Sara R Newman, Jon O. Freeman, Tyler E Johnson, Daniel E Amster, Allen R Chacko, Christine J Sohn
Publikováno v:
Organic & Biomolecular Chemistry. 17:3195-3201
Botryococcene is a branched triterpene produced by the algae Botryococcus braunii. Hydrocracking botryococcene yields a variety of combustible fuels such as gasoline and jet fuel. Engineering host systems and proteins involved in the biosynthesis of
Autor:
Chang-Uk Lee, Andrew J. Boydston, Saghar Nourian, John P. Toscano, Neal A. Yakelis, Derek C. Church
Publikováno v:
ACS Macro Letters. 6:46-49
We demonstrate concomitant release of HNO and small molecule organics from amphiphilic poly(norbornene)-based copolymers. This key function was achieved by incorporation of thermally labile oxazine units within random and block copolymer architecture
Publikováno v:
Organic & Biomolecular Chemistry. 14:5617-5621
We have investigated the reversible hetero-Diels-Alder reaction of 1,2-oxazines derived from a peralkylcyclopentadiene and a series of nitrosocarbonyl dienophiles. The nature of the dienophile was found to impart broad tunability to the dynamic chara
Publikováno v:
Polymer. 55:5980-5985
We have demonstrated the site-specific thermal activation of self-immolative polymers (SIPs) using a bicyclic oxazine as a temperature-sensitive triggering moiety. The oxazine-based trigger was installed at the junction of a SIP-poly(N,N-dimethylacry
Publikováno v:
The Journal of Organic Chemistry. 73:9657-9667
A convergent and highly stereocontrolled total synthesis of the cytotoxic macrolide (+)-superstolide A is described. Key features of this synthesis include the use of bimetallic linchpin 36b for uniting the C(1)-C(15) (43) and the C(20)-C(27) (38) fr
Autor:
Neal A. Yakelis, William R. Roush
Publikováno v:
The Journal of Organic Chemistry. 68:3838-3843
A stereoselective synthesis of the C(21)-C(26) fragment of superstolide A has been completed. The absolute and relative stereochemistry of intermediate 14 has been conclusively proven by NMR and X-ray diffraction methods. In the course of this work,
Publikováno v:
Inorganica Chimica Acta. 375:305-307
A new approach to the immobilization of organometallic complexes to monolayer surfaces is demonstrated using aldehyde-terminated self-assembled monolayers and a Cp ∗ Ir complex. The iridium complex is anchored to the surface by direct attachment of
Autor:
Neal A. Yakelis, William R. Roush
Publikováno v:
Organic Letters. 3:957-960
Lewis acid catalyzed intramolecular Diels-Alder reactions of trienes (E,E,Z)-1a-d, (E,E,Z)-4a-d, and (E,Z,Z)-7a,b are described. Trienes containing enal or enone dienophiles cyclize in excellent yield under mild conditions using substoichiometric amo
Autor:
Neal A. Yakelis, Robert G. Bergman
Publikováno v:
Organometallics. 24:3579-3581
A safe, convenient preparation of the reagent sodium tetrakis[(3,5-trifluoromethyl)phenyl]borate (NaBArF24) has been devised by utilizing a magnesium−bromine exchange reaction in the absence of metallic magnesium. Purified material was then rigorou
Publikováno v:
Tetrahedron Letters. 43:4885-4887
A stereoselective synthesis of the C(20)–C(26) fragment of superstolide A is described.